Neville F. Hacker - Hacker & Moores Essentials of Obstetrics and Gynecology

Hacker and Moore's ESSENTIALS OF OBSTETRICS AND GYNECOLOGY

Fifth Edition

Neville F. Hacker, MD

Professor of Gynaecologic Oncology Conjoint, University of New South Wales Director, Gynaecological Cancer Centre Royal Hospital for Women Sydney, Australia

Joseph C. Gambone, DO, MPH, Executive Editor

Professor Emeritus of Obstetrics and Gynecology David Geffen School of Medicine at UCLA Attending Physician, Ronald Reagan UCLA Medical Center Clinical Professor of Obstetrics and Gynecology Western University of Health Sciences College of Osteopathic Medicine of the Pacific Residency Education Consultant Arrowhead Regional Medical Center San Bernardino, California

Calvin J. Hobel, MD

Miriam Jacobs Chair in Maternal-Fetal Medicine Cedars-Sinai Medical Center Professor of Obstetrics and Gynecology Professor of Pediatrics David Geffen School of Medicine at UCLA Los Angeles, California

SAUNDERS

Front Matter

Copyright

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Philadelphia, PA 19103-2899

HACKER AND MOORE'S ESSENTIALS OF OBSTETRICS AND GYNECOLOGY ISBN: 978-1-4160-5940-0

International Edition ISBN: 978-0-8089-2416-6

Copyright 2010, 2004, 1998, 1992, 1986 by Saunders, an imprint of Elsevier Inc.

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Notice

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Editors assume any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book.

Library of Congress Cataloging-in-Publication Data

Hacker, Neville F.

Hacker and Moore's essentials of obstetrics and gynecology/Neville F. Hacker, Joseph C. Gambone, Calvin J. Hobel. 5th ed. p.; cm.

Rev. ed. of: Essentials of obstetrics and gynecology/[edited by] Neville F. Hacker, J. George Moore, Joseph C. Gambone. 4th ed. c2004.

Includes bibliographical references and index.

ISBN 9781416059400

1. Gynecology. 2. Obstetrics. I. Gambone, Joseph C. II. Hobel, Calvin J. III. Essentials of obstetrics and gynecology. IV. Title. V. Title: Essentials of obstetrics and gynecology.

[DNLM: 1. Obstetrics. 2. Genital Diseases, Female. 3. Pregnancy Complications. WQ 100 H118h 2010]

RG101.E87 2010

618dc22 2008025860

Acquisitions Editor: James Merritt

Developmental Editor: Christine Abshire

Publishing Services Manager: Linda Van Pelt

Design Direction: Gene Harris

Printed in China

Last digit is the print number: 9 8 7 6 5 4 3 2

Dedication

This edition is dedicated to our wives, Estelle Hacker, Marge (Morris) Gambone, and Marsha Lynn Hobel.

Their understanding and support for the time and effort required to complete this project was essential.

Contributors

Carolyn J. Alexander, MD, Assistant Clinical Professor, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Associate Director, Obstetrics and Gynecology Residency Program, Attending Physician, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California

Puberty and Disorders of Pubertal Development; Amenorrhea, Oligomenorrhea, and Hyperandrogenic Disorders

Ricardo Azziz, MD, MPH, MBA, Professor and Vice-Chair, Department of Obstetrics and Gynecology, Professor, Department of Medicine, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Chair, Department of Obstetrics and Gynecology, Director, Center for Androgen-Related Disorders, Cedars-Sinai Medical Center, Los Angeles, California

Puberty and Disorders of Pubertal Development; Amenorrhea, Oligomenorrhea, and Hyperandrogenic Disorders

Richard A. Bashore, MD, Professor Emeritus, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California

Fetal Surveillance During Labor; Uterine Contractility and Dystocia

Jonathan S. Berek, MD, MMS, Professor and Chair, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California

Ovarian Cancer; Gestational Trophoblastic Neoplasia

Narender N. Bhatia, MD, Professor, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California, Chief of Urogynecology, Director of Fellowship in Female Pelvic Medicine and Reconstructive Surgery, Harbor-UCLA Medical Center, Torrance, California

Genitourinary Dysfunction: Pelvic Organ Prolapse, Urinary Incontinence, and Infections

Richard P. Buyalos, Jr., MD, Attending Physician, Ronald Reagan UCLA Medical Center, University of California at Los Angeles, Los Angeles, California, Attending Physician, Community Memorial Hospital, Ventura, California, Attending Physician, Los Robles Hospital, Thousand Oaks, California

Puberty and Disorders of Pubertal Development

Lony C. Castro, MD, Professor and Chair, Department of Obstetrics and Gynecology, Western University of Health Sciences, College of Osteopathic Medicine of the Pacific, Pomona, California, Maternal Fetal Medicine Specialist, Obstetrics and Gynecology, Arrowhead Regional Medical Center, San Bernardino, California, Maternal Fetal Medicine Specialist, Obstetrics and Gynecology, Riverside County Regional Medical Center, Riverside, California