Frank W. Drislane - Blueprints Neurology

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Fifth edition

Copyright 2019 Wolters Kluwer.

Copyright 2014 Lippincott Williams & Wilkins, a Wolters Kluwer business. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at (products and services).

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Library of Congress Cataloging-in-Publication Data

Names: Drislane, Frank, author.

Title: Blueprints neurology / Frank W. Drislane.

Other titles: Blueprints.

Description: Fifth edition. | Philadelphia : Wolters Kluwer Health, [2019] | Series: Blueprints | Preceded by Blueprints neurology / Frank W. Drislane... [et al.]. 4th ed. c2014. | Includes bibliographical references and index.

Identifiers: LCCN 2018038438 | eISBN 9781496387417

Subjects: | MESH: Nervous System Diseases | Neurology | Examination Questions

Classification: LCC RC336 | NLM WL 18.2 | DDC 616.80076dc23 LC record available at https://lccn.loc.gov/2018038438

This work is provided as is, and the publisher disclaims any and all warranties, express or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.

This work is no substitute for individual patient assessment based upon healthcare professionals examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments.

Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturers package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work.

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B lueprints Neurology was first published more than 15 years ago as one of a series of books designed to help medical students prepare for USMLE Steps 2 and 3. As the study and practice of Medicine and Neurology and professional board examinations have evolved over the years, so too has Blueprints Neurology changed to assist students to learn Neurology in multiple evaluation and examination settings.

Examination preparation remains at the core of the series. To that end, the authors review the subject matter of the examination before each edition. The authors and editors work together to organize the most important, current, and factually correct material into a complete but concise review guide. Our goal remains integrating the depth of factual knowledge with the breadth of practice information in order to optimize both understanding and retention. We have been pleased to hear from our readers that the book is utilized by many medical students during their clinical rotations, as well as in preparation for shelf and board examinations. Residents in Internal Medicine, Emergency Medicine, and Family Practice, as well as nurse practitioners and physicians associates have found Blueprints helpful during the Neurology portion of their training. We believe the books applications have broadened with each edition due to the quality of our authors experience and their dedication to highlighting and clarifying a targeted range of basic but important topics that should be mastered.

Virtually all chapters are authored by experts in the content area, including neurologists from both academic medicine and busy private practice groups. They have incorporated suggestions received from medical students, faculty, clinicians, and program directors with regard to content and organization. Each chapter covers a single subject area for review; most can be read in under an hour. Key Points, highlighted throughout, facilitate quick review of the key concepts tested most frequently. Most chapters have Vignettes with characteristic clinical presentations to test ones review of the chapter. The 100 Questions at the end of the book are also written in the Clinical Vignette style used in USMLE and Board examinations, as recommended by student reviewers of the Blueprints series.

This fifth edition of Blueprints Neurology is the most thoroughly updated edition to date, with several new authors (generally closer in stage of education to the students for whom the book is written). It includes important updates on areas such as Multiple Sclerosis, Stroke, Epilepsy, Movement disorders and their genetic bases, Sleep disorders such as narcolepsy and cataplexy, and new drug and other treatments for each. Each chapter includes the most recent information and practice principles available and accepted at the time of publication.

We hope that readers of Blueprints Neurology will come to see the wonder of the human nervous system, how important it is to individuals in health and when it fails, and how the study and practice of Neurology is more helpful to patients than ever before.

Frank W. Drislane, MD
Aimee K. Boegle, MD, PhD
Alexandra Hovaguimian, MD
Courtney McIlduff, MD, MMSc
Andrew W. Tarulli, MD
Louis R. Caplan, MD

W e thank our patients for the opportunity of working with them and learning Neurology; our colleagues and teachers (and particularly, upon his retirement, Michael Ronthal, MBBCh) at Beth Israel Deaconess Medical Center Neurology department for teaching us more fascinating concepts about the nervous system; and our families for tolerating the many hours spent writing and revising this book.