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Leena Peltonen - Characterization of Pharmaceutical Nano- and Microsystems

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Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overviewEdited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale.The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker.Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines.Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics:An introduction to the analytical tools applied to determine particle size, morphology, and shapeCommon chemical approaches to drug system characterizationA description of solid-state characterization of drug systemsDrug release and permeation studiesToxicity and safety issuesThe interaction of drug particles with cellsPerfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Leena Peltonen: author's other books


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Table of Contents List of Tables Chapter 1 Chapter 2 Chapter 4 Chapter - photo 1
Table of Contents
List of Tables
  1. Chapter 1
  2. Chapter 2
  3. Chapter 4
  4. Chapter 5
  5. Chapter 6
  6. Chapter 7
  7. Chapter 9
  8. Chapter 10
List of Illustrations
  1. Chapter 1
  2. Chapter 2
  3. Chapter 3
  4. Chapter 4
  5. Chapter 5
  6. Chapter 6
  7. Chapter 7
  8. Chapter 8
  9. Chapter 9
  10. Chapter 10
Guide
Pages
Advances in Pharmaceutical Technology

A Wiley Book Series

Series Editors:

Dennis Douroumis, University of Greenwich, UK

Alfred Fahr, FriedrichSchiller University of Jena, Germany

Jurgen Siepmann, University of Lille, France

Martin Snowden, University of Greenwich, UK

Vladimir Torchilin, Northeastern University, USA

Titles in the Series

HotMelt Extrusion: Pharmaceutical Applications

Edited by Dionysios Douroumis

Drug Delivery Strategies for Poorly WaterSoluble Drugs

Edited by Dionysios Douroumis and Alfred Fahr

Computational Pharmaceutics: Application of Molecular Modeling in Drug Delivery

Edited by Defang Ouyang and Sean C. Smith

Pulmonary Drug Delivery: Advances and Challenges

Edited by Ali Nokhodchi and Gary P. Martin

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

Edited by Ryan Donnelly and Raj Singh

Drug Delivery Systems for Tuberculosis Prevention and Treatment

Edited by Anthony J. Hickey

Continuous Manufacturing of Pharmaceuticals

Edited by Peter Kleinebudde, Johannes Khinast, and Jukka Rantanen

Pharmaceutical Quality by Design

Edited by Walkiria S Schlindwein and Mark Gibson

In Vitro Drug Release Testing of Special Dosage Forms

Edited by Nikoletta Fotaki and Sandra Klein

Characterization of Pharmaceutical Nano and Microsystems

Edited by Leena Peltonen

Forthcoming Titles:

Process Analytics for Pharmaceuticals

Edited by Jukka Rantanen, Clare Strachan and Thomas De Beer

Mucosal Drug Delivery

Edited by Rene Holm

Basic Biopharmaceutics

Edited by Hannah Batchelor

Characterization of Pharmaceutical Nano and Microsystems

Edited by

LEENA PELTONEN
University of Helsinki, Finland

This edition first published 2021 2021 John Wiley Sons Ltd All rights - photo 2

This edition first published 2021

2021 John Wiley & Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Leena Peltonen to be identified as the author of the editorial material in this work has been asserted in accordance with law.

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Limit of Liability/Disclaimer of Warranty

In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of experimental reagents, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each chemical, piece of equipment, reagent, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress CataloginginPublication Data

Names: Peltonen, Leena Johanna, 1970- editor.

Title: Characterization of pharmaceutical nano- and microsystems / Leena

Johanna Peltonen.

Description: First edition. | Hoboken : Wiley, 2020. | Series: Advances in

pharmaceutical technology | Includes bibliographical references and

index.

Identifiers: LCCN 2020027861 (print) | LCCN 2020027862 (ebook) | ISBN

9781119414049 (cloth) | ISBN 9781119414032 (adobe pdf) | ISBN

9781119414025 (epub)

Subjects: LCSH: Pharmaceutical technology. | Nanotechnology. | Drug

development.

Classification: LCC RS192 .C522 2020 (print) | LCC RS192 (ebook) | DDC

615.1/9dc23

LC record available at https://lccn.loc.gov/2020027861

LC ebook record available at https://lccn.loc.gov/2020027862

Cover Design: Wiley

Cover Image: Inna Bigun/Shutterstock

List of Contributors

Malgorzata Iwona Adamczak, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway; and GE Healthcare, Pharmaceutical Diagnostics, Oslo, Norway

Osmo Antikainen, Faculty of Pharmacy, University of Helsinki, Finland

Cludia Azevedo, INEB Instituto de Engenharia Biomdica; i3S Instituto de Investigao e Inovao em Sade; and Instituto de Cincias Biomdicas Abel Salazar, Universidade do Porto, Portugal

Erem Bilensoy, Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Turkey

Preshita P. Desai, Western University of Health Sciences, Pomona, California, USA

Martin Dransk, Czech Academy of Sciences, Prague, Czech Republic

Nazl Erdoar, Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Turkey

Nazanin Zanjanizadeh Ezazi, Drug Research Program, University of Helsinki, Finland

Paulo J. Ferreira, CIEPQPF, Department of Chemical Engineering, University of Coimbra, Portugal

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