Vincent T. DeVita Jr. - DeVita, Hellman, and Rosenbergs Cancer: Principles & Practice of Oncology

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10th Edition

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Library of Congress Cataloging-in-Publication Data

Devita, Hellman, and Rosenbergs cancer : principles & practice of oncology / editors, Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg ; with 404 contributing authors.10th edition.

p. ; cm.

Cancer

Includes bibliographical references and index.

ISBN 978-1-4511-9294-0 (hardback)ISBN 1-4511-9294-0 (hardback)

I. DeVita, Vincent T., Jr., 1935- , editor. II. Lawrence, Theodore S., editor. III. Rosenberg, Steven A., editor.

IV. Title: Cancer.

[DNLM: 1. Neoplasms. QZ 200]

RC261

616.99'4dc23

2014035783

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In memoriam

Jonathan W. Pine, Jr.

19572013

We dedicate this edition to Jonathan Pine, our colleague and Senior Executive Editor at Wolters Kluwer Health, whose relaxed style belied his fierce dedication to turning out a quality book.

Amy P. Abernethy, MD, PhD

Director, Center for Learning Health Care

Duke Clinical Research Institute

Director, Duke Cancer Care Research Program

Duke Cancer Institute

Associate Professor

Division of Medical Oncology

Department of Medicine

Duke University School of Medicine

Durham, North Carolina

Ghassan Abou-Alfa, MD

Associate Attending

Department of Medicine

Memorial Sloan-Kettering Cancer Center

Associate Professor

Department of Medicine

Weill Cornell Medical College

New York, New York

Ross A. Abrams, MD

Chairman and Hendrickson Professor of Radiation Oncology

Rush University Medical Center

Chicago, Illinois

Nadeem R. Abu-Rustum, MD

Professor

Weill Medical College of Cornell University

Chief, Gynecologic Oncology Service

Memorial Sloan-Kettering Cancer Center

New York, New York

Gregory P. Adams, PhD

Associate Professor Developmental Therapeutics Program

Director of Biological Research and Therapeutics

Fox Chase Cancer Center

Philadelphia, Pennsylvania

Anupriya Agarwal, PhD

Research Assistant Professor

The Knight Cancer Center

Oregon Health & Science University

Portland, Oregon

Bharat B. Aggarwal, PhD

Professor of Cancer Research

Professor of Cancer Medicine (Biochemistry)

Chief, Cytokine Research Laboratory

Department of Experimental Therapeutics

The University of Texas MD Anderson Cancer Center

Houston, Texas

Shahab Ahmed, MD

Data Analyst, Department of Gastrointestinal Medical Oncology

The University of Texas MD Anderson Cancer Center

Houston, Texas

Manmeet S. Ahluwalia, MD, FACP

Associate Professor, Department of Medicine

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

Associate Director, Clinical Trials, Operations

The Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center

Neurological Institute

Cleveland Clinic

Cleveland, Ohio

Kaled M. Alektiar, MD

Member Department of Radiation Oncology

Memorial Sloan-Kettering Cancer Center

New York, New York

James M. Allan, DPhil

Northern Institute for Cancer Research

Faculty of Medicine

Newcastle University

Newcastle-upon-Tyne, United Kingdom

Matthew L. Anderson, MD, PhD, FACOG

Assistant Professor

Division of Gynecology Oncology

Director of Clinical Research (Gynecology)

Department of Obstetrics & Gynecology

Research Member, Dan L. Duncan Cancer Center

Baylor College of Medicine

Houston, Texas