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Douglas A. Levine et al. - Handbook for Principles and Practice of Gynecologic Oncology

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Easy to read and designed for on-the-spot reference, Handbook for Principles and Practice of Gynecologic Oncology, 2nd Edition is a comprehensive yet concise guide for fellows, residents, and specialist trainees in the diagnosis and management of gynecologic cancers. Youll find authoritative coverage of the latest developments in the field, streamlined data that support treatment recommendations, and helpful algorithms and tables included throughout.
  • Learn from two new co-editors, Drs. Dizon and Yashar, who share their expertise in gynecologic medical oncology and gynecologic radiation oncology.
  • Progress logically through each chapter from incidence and etiology to diagnosis and treatment.
  • An ideal companion to Barakat, Markman, and Randalls Principles and Practice of Gynecologic Oncology, 6th Edition.
Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to:
  • Complete content with enhanced navigation.
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Handbook for PRINCIPLES AND PRACTICE OF GYNECOLOGIC ONCOLOGY SECOND EDITION - photo 1
Handbook for
PRINCIPLES AND
PRACTICE OF
GYNECOLOGIC
ONCOLOGY

SECOND EDITION

Handbook for
PRINCIPLES AND PRACTICE OF GYNECOLOGIC ONCOLOGY

EDITION

E D I T O R S

Douglas A. Levine, MD

Associate Attending Surgeon
Gynecology Service, Department of Surgery
Memorial Sloan Kettering Cancer Center
New York, New York

Don S. Dizon, MD, FACP

Clinical Co-Director, Gynecologic Oncology
Director, Oncology Sexual Health Clinic
Massachusetts General Hospital Cancer Center
Harvard Medical School
Boston, Massachusetts

Catheryn M. Yashar, MD

Professor, Department of Radiation Medicine and Applied Sciences
University of CaliforniaSan Diego
Moores Cancer Center
La Jolla, California

Richard R. Barakat, MD, FACOG, FACS

Deputy Physician-in-Chief
Regional Care Network and MSK Cancer Alliance
Ronald O. Perelman Chair in Gynecologic Surgery
Memorial Sloan Kettering Cancer Center
New York, New York

Andrew Berchuck, MD

Director, Division of Gynecologic Oncology
Department of Obstetrics and Gynecology
Director, Gynecologic Cancer Program
Duke Cancer Institute
Duke University Medical Center
Durham, North Carolina

Maurie Markman, MD

Senior Vice President for Clinical Affairs
National Director of Medical Oncology
Cancer Treatment Centers of America
Philadelphia, Pennsylvania

Marcus E. Randall, MD, FACR, FASTRO

Professor and Chair, Department of Radiation Medicine
Markey Foundation Endowed Chair
University of Kentucky
Chief, Ambulatory Services
UK HealthCare
Lexington, Kentucky

Acquisitions Editor Julie Goolsby Senior Product Development Editor Emilie - photo 2

Acquisitions Editor: Julie Goolsby

Senior Product Development Editor: Emilie Moyer

Editorial Assistant: Brian Convery

Marketing Manager: Stephanie Kindlick

Production Project Manager: David Saltzberg

Design Coordinator: Stephen Druding

Manufacturing Coordinator: Beth Welsh

Prepress Vendor: SPi Global

2nd Edition

Copyright 2015 Wolters Kluwer

Copyright 2010 Lippincott Williams & Wilkins, a Wolters Kluwer business. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at permissions@lww.com, or via our website at lww.com (products and services).

987654321

Printed in China


Library of Congress Cataloging-in-Publication Data

Handbook for principles and practice of gynecologic oncology / editors, Douglas A. Levine [and 6 others]. 2nd edition.

p. ; cm.

Abridgement of: Principles and practice of gynecologic oncology. 6th ed. / edited by Richard R. Barakat [et al.]. c2013.

Includes bibliographical references and index.

ISBN 978-1-4963-0642-5 (alk. paper)

I. Levine, Douglas A., editor.II. Principles and practice of gynecologic oncology. Abridgement of (work):

[DNLM:1. Genital Neoplasms, Female.WP 145]

RC280.G5

616.99'465dc23

2014044272


This work is provided as is, and the publisher disclaims any and all warranties, express or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.

This work is no substitute for individual patient assessment based upon healthcare professionals examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments.

Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturers package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work.

LWW.com

This book is dedicated to all those who care for our patients on the wards and in the operating rooms, and to our families who support us.

CONTRIBUTORS

Jose Alejandro Rauh-Hain, MD

Clinical Fellow, Gynecologic Oncology
Massachusetts General Hospital
Harvard Medical School
Boston, Massachusetts

Joyce N. Barlin, MD

Assistant Professor
Department of Obstetrics and Gynecology
Albany Medical College, Albany Medical Center
Attending Physician
Womens Cancer Care Associates
Albany, New York

Rachel M. Clark Sisodia, MD

Instructor
Department of Obstetrics, Gynecology, and Reproductive Biology
Harvard Medical School
Attending Physician
Division of Gynecologic Oncology
Department of Obstetrics and Gynecology
Massachusetts General Hospital
Boston, Massachusetts

Don S. Dizon, MD, FACP

Clinical Co-Director, Gynecologic Oncology
Director, Oncology Sexual Health Clinic
Massachusetts General Hospital Cancer Center
Harvard Medical School
Boston, Massachusetts

Tracilyn R. Hall, MD

Clinical Fellow in Obstetrics and Gynecology
Division of Gynecologic Oncology
Massachusetts General Hospital, Harvard School of Medicine
Boston, Massachusetts

Douglas A. Levine, MD

Associate Attending Surgeon
Gynecology Service, Department of Surgery
Memorial Sloan Kettering Cancer Center
New York, New York

Sharon M. Lu, MD

Resident Physician
Department of Radiation Oncology
Kaiser Permanente Southern California
Los Angeles, California

Samith Sandadi, MD, MSc

Gynecologic Oncologist
Florida Gynecologic Oncology
Fort Myers, Florida

Catheryn M. Yashar, MD

Professor, Department of Radiation
Medicine and Applied Sciences
University of California San Diego
Moores Cancer Center
La Jolla, California

PREFACE

Medicine is a field in continual evolution, and gynecologic oncology is no exception. Indeed, the field is constantly changing as new data are published that further our understanding and treatment approaches to these cancers. As a result, we have created the PPGO Handbook as a complement to its parent textbook,

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