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Faiz M. Khan - Khan’s Treatment Planning in Radiation Oncology

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This unique, full-color reference offers a total team approach to radiation oncology treatment planning, incorporating the newest imaging techniques and offering a comprehensive discussion of clinical, physical, biological and technical aspects. A clear focus on the application of physical and clinical concepts to solve treatment planning problems helps you provide effective, state-of-the-art care for cancer patients. With authoritative coverage of the latest in sophisticated radiation oncology treatment modalities, the 4th Edition of Khans Treatment Planning in Radiation Oncology is an essential resource for the radiation oncologist, medical physicist, dosimetrist, and radiation therapist.
New to this edition:
  • Up-to-date material throughout reflects the most current practices in radiation oncology treatment.
  • New chapters discuss the pros and cons of recent developments in the field: Role of Protons vs. Photons in Modern Radiotherapy: Clinical Perspective, Intensity-Modulated Proton Therapy, and Radiobiology of Hypofractionated Regimens for SRS and SBRT.
  • New contributors bring a fresh perspective and provide current insight in their areas of expertise.
  • New Key Points and Study Questions at the end of each chapter online help you assess your understanding of the material.
  • Discussions of the scientific background and the key aspects of clinical approach ensure that you gain a well-rounded understanding of how to plan treatment from both a technical and a clinical perspective.
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FOURTH EDITION KHANS Treatment Planning in Radiation Oncology EDITORS Faiz M - photo 1
FOURTH EDITION KHANS Treatment Planning in Radiation Oncology EDITORS Faiz M - photo 2

FOURTH EDITION

KHANS
Treatment Planning in Radiation Oncology

EDITORS

Faiz M. Khan, PhD

Professor Emeritus

Department of Radiation Oncology

University of Minnesota Medical School

Minneapolis, Minnesota

John P. Gibbons, PhD

Chief Medical Physicist

Department of Radiation Oncology

Ochsner Health System

New Orleans, Louisiana

Paul W. Sperduto, MD, MPP, FASTRO

Radiation Oncologist

Minneapolis Radiation Oncology

Minneapolis, Minnesota

Acquisitions Editor Julie Goolsby Senior Product Development Editor Emilie - photo 3

Acquisitions Editor: Julie Goolsby

Senior Product Development Editor: Emilie Moyer

Editorial Assistant: Brian Convery

Production Project Manager: Alicia Jackson

Design Coordinator: Joan Wendt, Elaine Kasmer

Illustration Coordinator: Jennifer Clements

Manufacturing Coordinator: Beth Welsh

Marketing Manager: Rachel Mante Leung

Prepress Vendor: Aptara, Inc.

4th edition

Copyright 2016 Wolters Kluwer

Copyright 2012 Lippincott Williams & Wilkins, a Wolters Kluwer business. Copyright 2006 Lippincott Williams & Wilkins, a Wolters Kluwer business. Copyright 1998 by Lippincott Williams & Wilkins. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at (products and services).

9 8 7 6 5 4 3 2 1

Printed in China

Library of Congress Cataloging-in-Publication Data

Names: Khan, Faiz M., editor. | Gibbons, John P., Jr., editor. | Sperduto,

Paul W., editor.

Title: Khans treatment planning in radiation oncology / editors, Faiz M. Khan,

John P. Gibbons, Paul W. Sperduto.

Other titles: Treatment planning in radiation oncology.

Description: Fourth edition. | Philadelphia : Wolters Kluwer [2016] |

Preceded by Treatment planning in radiation oncology / editors, Faiz M. Khan,

Bruce J. Gerbi. 3rd ed. c2012. | Includes bibliographical references and

index.

Identifiers: LCCN 2016004611 | ISBN 9781469889979

Subjects: | MESH: Neoplasmsradiotherapy | Radiotherapy Planning,

Computer-Assisted | Radiation Oncologymethods

Classification: LCC RC271.R3 | NLM QZ 269 | DDC 616.99/40642dc23

LC record available at http://lccn.loc.gov/2016004611

This work is provided as is, and the publisher disclaims any and all warranties, express or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.

This work is no substitute for individual patient assessment based upon healthcare professionals examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments.

Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturers package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work.

LWW.com

To Kathy, my wife and companion of fifty years:

Happy Anniversary, My Love.

Faiz M. Khan

To my wife Nicole, for her continued patience and support

John P. Gibbons

To Jody, Luke, Maria, and Will for their love and laughter and my patients who provide me the privilege of caring for them in times of greatest need.

Paul W. Sperduto

Contributors

Judy A. Adams, CMD

Director of Dosimetry

Department of Radiation Oncology

Massachusetts General Hospital Cancer Center

Boston, Massachusetts

Fiori Alite, MD

Department of Radiation Oncology

Stritch School of Medicine

Loyola University

Maywood, Illinois

John A. Antolak, PhD

Associate Professor & Consultant

Department of Radiation Oncology

Mayo Clinic

Rochester, Minnesota

James M. Balter, PhD

Professor

Radiation Oncology Department

University of Michigan

Ann Arbor, Michigan

Christopher Beltran, PhD

Mayo Clinic

Department of Radiation Oncology

Rochester, Minnesota

Rachel C. Blitzblau, MD, PhD

Assistant Professor

Department of Radiation Oncology

Duke University School of Medicine

Attending Physician, Radiation Oncology

Duke University Medical Center

Durham, North Carolina

Stefan Both, PhD

Associate Attending

Medical Physics Department

Memorial Sloan Kettering Cancer Center

New York, New York

Frank J. Bova, PhD, FACR, FAAPM, FAAPM

Albert E. and Birdie W. Professor of Computer-Assisted Stereotactic Neurosurgery

University of Florida College of Medicine

Gainesville, Florida

Jason Chan, MD

Resident in Training

Department of Radiation Oncology

University of California San Francisco

San Francisco, California

Albert Chang, MD, PhD

Assistant Professor in Residence

Departments of Radiation Oncology and Urology

University of California, San Francisco

San Francisco, California

George T. Y. Chen, PhD

Department of Radiation Oncology

Massachusetts General Hospital and Harvard Medical School

Boston, Massachusetts

Zhe (Jay) Chen, PhD

Professor

Department of Therapeutic Radiology

Yale University School of Medicine

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