Dwight E. Heron - Head and Neck Cancer

Radiation Medicine Rounds

Charles R. Thomas, Jr., MD

Editor-in-Chief

Professor and Chair
Department of Radiation Medicine
Professor, Division of Hematology/Oncology
Department of Medicine
Knight Cancer Institute
Oregon Health & Science University Cancer Institute
Portland, Oregon

Editorial Board

Indrin J. Chetty, PhD
Detroit, Michigan

T.J. Fitzgerald, MD
Worcester, Massachusetts

C. David Fuller, MD
Houston, Texas

Iris Gibbs, MD
Stanford, California

Karyn A. Goodman, MD
New York, New York

Chandan Guha, MD, PhD
Bronx, New York

Michele Y. Halyard, MD
Scottsdale, Arizona

Dwight E. Heron, MD
Pittsburgh, Pennsylvania

Robert S. Lavey, MD, MPH
Tampa, Florida

A.J. Mundt, MD
San Diego, California

Ramesh Rengan, MD, PhD
Philadelphia, Pennsylvania

Sharon A. Spencer, MD
Birmingham, Alabama

Oscar Streeter, Jr., MD
Washington, DC

Charles R. Thomas, Jr., MD
Portland, Oregon

Forthcoming Issue

Gynecologic Cancer
A. J. Mundt, Catheryn Yashar, and Loren Mell
Guest Editors

Radiation Medicine Rounds

VOLUME 2, ISSUE 2

Head and Neck Cancer

Guest Editors

Dwight E. Heron, MD

UPMC Shadyside Radiation Oncology
Pittsburgh, Pennsylvania

Roy B. Tishler, MD, PhD

Brigham and Womens Hospital
Boston, Massachusetts

Acquisitions Editor: Richard Winters
Cover Design: Joe Tenerelli
Compositor: Newgen Imaging
Printer: Hamilton Printing

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ISSN: 2151-4208
ISBN: 978-1-936287-36-9

Library of Congress Cataloging-in-Publication Data

Head and neck cancer / guest editors, Dwight E. Heron, Roy B. Tishler.

p.; cm. (Radiation medicine rounds, ISSN 2151-4208 ; v. 2, issue 2)

Includes bibliographical references and index.

ISBN 978-1-936287-36-9

1. HeadCancerRadiotherapy. 2. NeckCancerRadiotherapy. I. Heron, Dwight. II. Tishler, Roy B. III. Series: Radiation medicine rounds ; v. 2, issue 2. 2151-4208

[DNLM: 1. Head and Neck Neoplasmsdrug therapy. 2. Head and Neck
Neoplasmsradiotherapy. W1 RA162HD v.2 no.2 2011 / WE 707]

RC280.H4H38443 2011

616.99[H11032]491dc23 2011026509

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Contents

Intensity-Modulated Radiation Therapy for Head and Neck Cancer: A Decade of Experience Demonstrates Improved Patient Outcomes
G. Brandon Gunn and Adam S. Garden

Concurrent Chemotherapy and Radiation for Head and Neck Cancer
Roy B. Tishler

Targeted Therapy for Squamous Cell Carcinoma of the Head and Neck
Sharon A. Spencer

Induction Chemotherapy in Head and Neck Cancer: A Standard of Care
Sewanti Limaye and Robert I. Haddad

Postoperative Management Following Transoral Robotic Surgery for Oropharyngeal Carcinomas
Harry Quon and Benjamin Goldsmith

Particle Therapy in Treatment of Head and Neck Cancer
Danielle N. Margalit and Annie W. Chan

Optimizing Treatment Strategies in Recurrent Head and Neck Cancers
Gregory J. Kubicek and Dwight E. Heron

Outcomes Research in Head and Neck Cancer
David J. Sher

Palliative Care and Symptom Management in the Head and Neck Cancer Patient
Tracy A. Balboni

Toxicity Assessment and Reporting in Radiotherapy of Head and Neck Cancer
Kenneth Jensen and Cai Grau

Biomarkers and Molecular-Targeted Therapeutics in Squamous Cell Carcinoma of the Head and Neck
Raymond L. Chai and Jennifer R. Grandis

Image-Guidance in the Radiotherapeutic Management of Head and Neck Cancer: Current Strategies and Ongoing Challenges
Allen M. Chen and James A. Purdy

FROM THE EDITOR-IN-CHIEF

Radiation Medicine Rounds is a hard cover, periodical series that is designed to provide an up-to-date review of a dedicated radiation medicine topic of interest to clinicians and scientists who are involved in the care of patients receiving radiotherapy. It is intended to serve as both a reference and instructional tool by students, housesta?, fellows, practicing clinicians, medical physicists, cancer/radiobiologists, and interdisciplinary col-leagues throughout the oncology spectrum.

The current issue, Head and Neck Cancer, is a successful attempt to concisely summarize one of the dis-eases that has served as a paradigm for implementation of emerging technology and understanding of cancer biology over the past two decades. Our volume editors, Dr. Roy Tishler and Dr. Dwight Heron, have been able to get some of the leading thought leaders in radiotherapy of the head and neck to contribute to an up-to-date summary of the role of radiotherapy in this complex malignancy of the upper areodigestive tract. On behalf of the rest of the RMR editorial board, Roy and Dwight are to be congratulated for developing such a reliable resource for the head and neck cancer community.

D R . C HARLES R. T HOMAS , J R .
Series Editor-in-Chief
Radiation Medicine Rounds
Portland, Oregon