Berek & Novaks
Gynecology
Fifteenth Edition
Jonathan S. Berek , MD, MMS
Professor and Chair
Department of Obstetrics and Gynecology
Stanford University School of Medicine
Director, Stanford Women's Cancer Center
Stanford Cancer Institute
Stanford, California
Editorial Assistant & Design
Deborah L. Berek, MA
Illustrations by
Timothy C. Hengst, CMI, FAMI
George Barile
Acquisitions Editor: Sonya Seigafuse
Product Manager: Nicole Walz
Vendor Manager: Alicia Jackson
Senior Manufacturing Manager: Benjamin Rivera
Marketing Manager: Kimberly Schonberger
Design Coordinator: Holly Reid McLaughlin
Production Service: Aptara, Inc.
2012 by LIPPINCOTT WILLIAMS & WILKINS, a WOLTERS KLUWER business
2007, 2002, and 1996 by Lippincott Williams & Wilkins
1988, 1981, and 1975 by Williams & Wilkins
Two Commerce Square
2001 Market Street
Philadelphia, PA 19103 USA
LWW.com
All rights reserved. This book is protected by copyright. No part of this book may be reproduced in any form by any means, including photocopying, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright.
Printed in the United States of America
Library of Congress Cataloging-in-Publication Data
Berek & Novak's gynecology. -- 15th ed. / [edited by] Jonathan S. Berek ; editorial assistant & design,
Deborah L. Berek ; illustrations by Timothy C. Hengst, George Barile.
p. ; cm.
Berek and Novak's gynecology
Gynecology
Includes bibliographical references and index.
Summary: Berek and Novak's Gynecology is the gold standard text in general gynecology serving both as a comprehensive reference and a practical, clinically-oriented text. This reference is not only a must-have product for residents in training, but it offers information for the practicing physician. The book covers the entire spectrum of women's healthcare by offering guidance for the management of specific gynecologic conditions in eight sections. The first two sections cover principles of practice and initial assessment and the relevant basic science. The third section is on preventive and primary care for women, and the remaining five sections are directed at methods of diagnosis and management in general gynecology, operative general gynecology, urogynecology and pelvic reconstructive surgery, reproductive endocrinology, and gynecologic oncology--Provided by publisher.
ISBN 978-1-4511-1433-1 (hardback : alk. paper)
I. Berek, Jonathan S. II. Novak, Emil, 1883--1957. III. Title: Berek and Novak's gynecology.
IV. Title: Gynecology.
[DNLM: 1. Genital Diseases, Female. 2. Gynecology--methods. 3. Pregnancy Complications. WP 100]
618.1--dc23 2011035507
Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of the information in a particular situation remains the professional responsibility of the practitioner.
The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug.
Some drugs and medical devices presented in the publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in their clinical practice.
To purchase additional copies of this book, call our customer service department at (800) 638-3030 or fax orders to (301) 223-2320. International customers should call (301) 223-2300.
Visit Lippincott Williams & Wilkins on the Internet: at LWW.com. Lippincott Williams & Wilkins customer service representatives are available from 8:30 am to 6 pm, EST.
10 9 8 7 6 5 4 3 2 1
To Deborahtogether in life and in print.
Contributors
Lisa N. Abaid, MD, MPH
Gynecologic Oncology Associates
Newport Beach, California
Jean R. Anderson, MD
Professor
Department of Gynecology and Obstetrics
Johns Hopkins University School of Medicine
Baltimore, Maryland
Mira Aubuchon, MD
Assistant Professor
Department of Obstetrics, Gynecology and
Women's Health
University of Missouri School of Medicine
Columbia, Missouri
Valerie L. Baker, MD
Assistant Professor
Department of Obstetrics and Gynecology
Stanford University School of Medcine
Stanford, California
David A. Baram, MD
Clinical Assistant Professor
Department of Obstetrics and Gynecology
University of Minnesota School of Medicine
Regions Hospital
St. Paul, Minnesota
Rosemary Basson, MD
Clinical Professor
Departments of Psychiatry and Obstetrics & Gynecology
University of British Columbia
University of British Columbia Centre for Sexual Medicine
Vancouver, Canada
Ross S. Berkowitz, MD
William H. Baker Professor of Gynecology
Department of Obstetrics and Gynecology
Harvard Medical School
Director of Gynecology and Gynecologic Oncology
Brigham and Women's Hospital
Dana Farber Cancer Institute
Boston, Massachusetts
Andrew I. Brill, MD
Director of Minimally Invasive Gynecology
Department of Obstetrics and Gynecology
California Pacific Medical Center
San Francisco, California
Lieutenant Colonel Richard O. Burney, MD, MSc
Department of Obstetrics and Gynecology
Madigan Healthcare System
United States Army Medical Command
Tacoma, Washington
Joanna M. Cain, MD
Professor and Vice Chair
Department of Obstetrics and Gynecology
University of Massachusetts Medical School
Worcester, Massachusetts
Daniel L. Clarke-Pearson, MD
Robert A. Ross Distinguished Professor and Chair
Department of Obstetrics and Gynecology