Gammelgaard Bente - Introduction to pharmaceutical analytical chemistry

1. Chapter 1
2. Chapter 2
3. Chapter 3
4. Chapter 4
5. Chapter 5
6. Chapter 7
7. Chapter 8
8. Chapter 9
9. Chapter 11
10. Chapter 12
11. Chapter 15
12. Chapter 16
13. Chapter 17
14. Chapter 18
15. Chapter 20
16. Chapter 21

1. Chapter 1
2. Chapter 3
3. Chapter 4
4. Chapter 5
5. Chapter 6
6. Chapter 7
7. Chapter 8
8. Chapter 9
9. Chapter 10
10. Chapter 11
11. Chapter 12
12. Chapter 13
13. Chapter 14
14. Chapter 15
15. Chapter 16
16. Chapter 17
17. Chapter 18
18. Chapter 20
19. Chapter 21

STIG PEDERSEN-BJERGAARD

Department of Pharmacy, University of Oslo, Norway and Department of Pharmacy, University of Copenhagen, Denmark

BENTE GAMMELGAARD

Department of Pharmacy, University of Copenhagen, Denmark

TRINE GRNHAUG HALVORSEN

Department of Pharmacy, University of Oslo, Norway

Second Edition

This edition first published 2019

2019 John Wiley & Sons Ltd

Edition history:

John Wiley & Sons Ltd. (1e, 2012).

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Stig PedersenBjergaard, Bente Gammelgaard and Trine Grnhaug Halvorsen to be identified as the authors of the editorial material in this work has been asserted in accordance with law.

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Library of Congress CataloginginPublication Data

Names: Pedersen-Bjergaard, Stig, author. | Gammelgaard, Bente, author. |

Halvorsen, Trine G. (Trine Grnhaug), 1975- author.

Title: Introduction to pharmaceutical analytical chemistry / Stig

Pedersen-Bjergaard, Department of Pharmacy, University of Oslo, Norway and

Department of Pharmacy, University of Copenhagen, Denmark, Bente

Gammelgaard, Department of Pharmacy, University of Copenhagen,

Denmark,Trine Grnhaug Halvorsen, Department of Pharmacy, University of Oslo,

Norway.

Other titles: Introduction to pharmaceutical chemical analysis.

Description: Second edition. | Hoboken, NJ : Wiley, 2019. | Revision of:

Introduction to pharmaceutical chemical analysis / Steen Hansen, Stig

Pedersen-Bjergaard, Knut Rasmussen. 2012. | Includes bibliographical

references and index. |

Identifiers: LCCN 2018051420 (print) | LCCN 2018053744 (ebook) | ISBN

9781119362722 (Adobe PDF) | ISBN 9781119362753 (ePub) | ISBN 9781119362722

(paperback)

Subjects: LCSH: DrugsAnalysis. | Pharmaceutical chemistry. | BISAC: SCIENCE

/ Chemistry / Analytic.

Classification: LCC RS189 (ebook) | LCC RS189 .H277 2019 (print) | DDC

615.1/9dc23

LC record available at https://lccn.loc.gov/2018051420

Cover design: Wiley

This textbook is an extensive revision of Introduction to Pharmaceutical Analysis from 2012. We have revised the manuscript totally, and updated the content according to current practice in pharmaceutical analytical chemistry, and according to current versions of European and United States Pharmacopeia. Additionally, we have added a new chapter on chemical analysis of biopharmaceuticals, improved the illustrations throughout and provided illustrations in colour. The intention of these efforts has been to provide the reader with a textbook at the level expected in 2018.

We have changed the title to emphasize that this textbook is about analytical chemistry, and that the applications described are all related to pharmaceuticals. However, the philosophy is the same as with the first edition. The textbook is primarily for pharmacy and chemistry students (and other scientists approaching the pharmaceutical sciences) at university level, requesting basic knowledge on chemical analysis of pharmaceutical ingredients and preparations, and chemical analysis of drug substances in biological fluids. In the first part of the textbook, we teach the fundamentals of the main analytical techniques. Compared to textbooks in pure analytical chemistry, we go into less detail but we still teach to a level where the reader can understand the details in current pharmacopeia and bioanalytical methods. The second part of the textbook is unique, as we focus on identification, purity testing and assay of pharmaceutical ingredients, identification and quantitation of active ingredients in pharmaceutical preparations, and identification and quantitation of drugs in biological fluids. Such systematic discussion of pharmaceutical applications is not found in any other textbook on the market.