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Shailendra K. Saxena - NanoBioMedicine

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Shailendra K. Saxena NanoBioMedicine

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Editors Shailendra K Saxena and S M Paul Khurana NanoBioMedicine - photo 1
Editors
Shailendra K. Saxena and S. M. Paul Khurana
NanoBioMedicine
Editors Shailendra K Saxena Centre for Advanced Research King Georges - photo 2
Editors
Shailendra K. Saxena
Centre for Advanced Research, King Georges Medical University, Lucknow, India
S. M. Paul Khurana
Amity University of Biotechnology, Amity University Haryana, Gurgaon, India
ISBN 978-981-32-9897-2 e-ISBN 978-981-32-9898-9
https://doi.org/10.1007/978-981-32-9898-9
Springer Nature Singapore Pte Ltd. 2020
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd.

The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Dedicated to theParents&Familywho believed in academics as the way forward for an intelligent mind and to theTeacherswho introduced us to the subject and nurtured over interest in it.

Foreword
Preface Although we are in the twenty-first century having most of the advanced - photo 3
Preface

Although we are in the twenty-first century having most of the advanced technologies in hand, yet communicable and noncommunicable diseases are majorly responsible for mortality due to scarcity of potential therapeutics and effective differential diagnostics. This book,NanoBioMedicine, provides a comprehensive overview of recent trends in various nanotechnology-based therapeutic and associated challenges. It focuses on various aspects and properties of communicable and noncommunicable diseases including nanotechnology-based approaches for development of effective therapeutics and differential diagnostics, which is imperative for safeguarding the human race from more loss of resources and economies due to disease burden. To overcome these issues and fill the gap, we hopeNanoBioMedicinewill provide a readily available resource in this area.

The quick development of nanoscience in the last few years has given an abundance of information into the physicochemical properties and biological performance of nanoscale materials that can be considered while utilizing nanotechnology for medicinal applications. The designing and application of nanoscale materials to alleviate complex diseased condition are of great interest. Nanoscale materials exhibit novel properties that can be exploited in various ways to design diagnostics and effective therapeutics. Nanomedicine involves multidisciplinary areas of sciences such as nanotechnology, nanoengineering and nanoscience interacting with the field of life sciences.

The elemental proposition upon which nanomedicine is pursued is nanoparticles, which are introduced into the body as foreign bodies and are subjected to the full armory of the bodys defense system labeled with antibody molecules targeting specific cells. Advances in the field of nanomedicine have come a long way since the time it was envisioned to be studied. The objectives and goal to establish global roadmaps in nanomedicine are guided by the need to take care of life-threatening clinical issues. Recent advancement in the field of nanomedicine has developed various tools for early diagnostics, treatment of complex diseases with high efficacy and specificity, and personalized therapy to improve the quality of life. This book is focusing on the various fields of medicine such as personalized medicine, cancer biology, stem cell therapy, regenerative medicine, infectious diseases, molecular diagnostics, biosensors, and nanotoxicology.

The editors of this book hope that this work might increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage. The editor and contributors report no conflict of interest.

Shailendra K. Saxena
S. M. Paul Khurana
Lucknow, India Gurugram, India
Acknowledgements

This book is conceptualized to present an updated account of the several state-of-the-art examples of the application of nanotechnology in the field of biomedical research. It also discusses the future prospects of targeting cancer stem cells through nanotherapeutic approaches for cancer treatment. It provides an updated account of the development of the virus-based nanoparticle system as vaccine therapy for the prevention and treatment of various infectious diseases. The book provides an unparalleled reservoir of information about nanotoxicology.

All these aspects are imperative for safeguarding human race from more loss due to various diseases. To overcome these issues and fill the gap, we hopeNanoBioMedicineshall provide a readily available resource in this area. The aim of this book is to provide a comprehensive overview of the recent trends in various nanotechnology-based therapeutics and challenges associated with its development.

We are overwhelmed in all humbleness and gratefulness to acknowledge our debt to all the contributors who trusted and supported us for this work. We hope they are as proud of this book as we are. We would also like to thank Springer Nature Publisher to consider this book for publication. All the reports cited in this book are taken with proper citation. However, any missed information is just unintentional and explicable.

Our research fellows and students are central to all our research and academic work. They are the motivating force behind anything constructive we do. They are truly brilliant and have a bright future. We would like to specially thank and express our gratitude to our mentors, teachers, and students who gave us strength to accomplish this. Also, we would like to thank the colleagues, family, and friends who gave a lot of encouragement and support during the work on this book.

A happy environment at home is essential for any kind of growth, and we thank our families especially talented wives and children.

Shailendra K. Saxena
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