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M. Mohamed Essa - Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management

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M. Mohamed Essa Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management
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Volume 24 Advances in Neurobiology Series Editor Arne Schousboe Department of - photo 1
Volume 24
Advances in Neurobiology
Series Editor
Arne Schousboe
Department of Drug Design & Pharmacology, University of Copenhagen, Copenhagen, Denmark

More information about this series at http://www.springer.com/series/8787

Editors
M. Mohamed Essa and M. Walid Qoronfleh
Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management
Editors M Mohamed Essa Food Science and Nutrition CAMS Sultan Qaboos - photo 2
Editors
M. Mohamed Essa
Food Science and Nutrition, CAMS, Sultan Qaboos University, Muscat, Oman
M. Walid Qoronfleh
World Innovation Summit for Health WISH, Qatar Foundation, Doha, Qatar
ISSN 2190-5215 e-ISSN 2190-5223
Advances in Neurobiology
ISBN 978-3-030-30401-0 e-ISBN 978-3-030-30402-7
https://doi.org/10.1007/978-3-030-30402-7
Springer Nature Switzerland AG 2020
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Foreword by Brian J. Wilkinson

It is a great pleasure to write a foreword for the bookPersonalized Food Intervention and Therapy for Autism Spectrum Disorder Managementedited by Drs. Mohamed Essa and M. Walid Qoronfleh, who have gained extensive experience in their respective scientific fields, including natural compounds and their potential beneficial effects on brain diseases and human health. It is highly commendable for these two scientists to author this book at this time when people are looking for something that would give them a good perspective on autism and the impact of food natural products on this disease spectrum.

Nowadays, there is great interest in investigations of food ingredients for their potential health benefits among the people suffering from autism spectrum disorder (ASD). We frequently fail to recognize the real benefit of traditional medicines and food natural ingredients despite the fact that they have been used for many centuries and are still being used widely in all cultures across the globe. This book provides a compelling perspective on the potential benefits of many edible items, including natural compounds, herbs, vegetables, fruits, grains, seeds, and nuts, for which substantial evidence now exist in the literature of their effectiveness against ASD. The individual chapters that are covered and written by experienced authors in their fields provide an additional value to the reader. The chapters are organized under three parts, covering the following: (1) Autism Spectrum Disorder from Background to Interplay of Genetic, Epigenetic, Environmental Risk Factors and Nutraceuticals, (2) Specific Foods and Nutrient Qualities in Autism, and (3) Food and Dietary Intervention and Therapy in Autism. This organization provides the reader a better basic understanding of pharmacological constituents, including their potential benefits against ASD.

Why this book is timely? Firstly, a greater proportion of the population in most developing and developed countries have become open-minded for the use of food ingredients and traditional medicines in spite of the use of allopathic medicines for treatment of diseases. Secondly, there is a huge increase in the prevalence of ASD globally, and until now, there are no proper medications to deal with symptoms or effectively manage comorbidities, behavior, performance, and food intolerances. Thirdly, misunderstanding and confusion exist among the parents of an ASD individual and their caregivers, and this book provides up-to-date clarification to the public.

Another notable factor in this book is that several chapters provide a better understanding of the mechanisms of the effects of various phytochemical constituents, such as sulforaphane, curcumin polyphenols (resveratrol), and flavonoids (luteolin). For instance, there is now an extensive literature on omega-3 fatty acids from nuts, showing they function as precursors for anti-inflammatory agents such as neuroprotectin D1 and resolvins, which might exert significant benefits on many neurological disorders including ASD.

In conclusion, I appreciate the efforts of the editors to publish this book, which is a great resource of composite information on food and autism. It should also be a good resource for parents with ASD children, dieticians, nutritionists, nutrition researchers, and other readers with interests in human health.

Brian J. Wilkinson
Foreword by Magid Abou-Gharbia

I was delighted when I received a request from Dr. M. Walid Qoronfleh to write a brief foreword for his book. I have known Dr. Qoronfleh for many years, and I have been impressed by his accomplishments in the biomedical field. During the last decade, Dr. Qoronfleh and I were among the team of Arab Expatiate Scientists (AES) who worked with Qatar Foundation to help in promoting Qatar research culture. In the process, we embarked on several new research initiatives in several important research areas. In the biomedical area, we also worked together on putting together and writing the planning document that was used to establish Qatar Biomedical Research Institute (QBRI), where significant biomedical research is currently being conducted today.

As a drug discovery researcher for over three decades in the pharmaceutical industry and academia, my research teams have always explored innovative approaches for design and synthesis of novel therapeutics for treatment of many diseases including central nervous system (CNS) disorders. We successfully discovered ten marketed drugs. Examples of CNS disorder drugs include the antidepressants Effexorand Pristiq, the sedative Sonata, and the analgesic Dezocine. While pursuing our drug discovery research, we were conscious of the importance of natural products therapeutic potential as well as the role of nutrition in preventing and ameliorating disease symptoms. Our efforts led to the discovery of natural products drugs like Mylotargand Toresil.

I am pleased to provide a foreword toPersonalized Food Intervention and Therapy for Autism Spectrum Disorder Management

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