Dan Longo - Harrisons Manual of Medicine, 18th Edition

EDITORS

Dan L. Longo, MD
Professor of Medicine, Harvard Medical School;
Senior Physician, Brigham and Womens Hospital; Deputy Editor, New England Journal of Medicine, Boston, Massachusetts; Adjunct Investigator, National Institute on Aging, National Institutes of Health, Bethesda, Maryland

Anthony S. Fauci, MD, ScD(HON)
Chief, Laboratory of Immunoregulation;
Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

Dennis L. Kasper, MD, MA(HON)
William Ellery Channing Professor of Medicine, Professor of Microbiology and Molecular Genetics, Harvard Medical School;
Director, Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, Boston, Massachusetts

Stephen L. Hauser, MD
Robert A. Fishman Distinguished Professor and Chairman, Department of Neurology, University of California, San Francisco, San Francisco, California

J. Larry Jameson, MD, PhD
Robert G. Dunlop Professor of Medicine; Dean, University of Pennsylvania Perelman School of Medicine; Executive Vice-President, University of Pennsylvania Health System, Philadelphia, Pennsylvania

Joseph Loscalzo, MD, PhD
Hersey Professor of the Theory and Practice of Medicine, Harvard Medical School; Chairman, Department of Medicine; Physician-in-Chief, Brigham and Womens Hospital, Boston, Massachusetts

Copyright 2013, 2009, 2005, 2002, 1998, 1995, 1991, 1988 by The McGraw-Hill Companies, Inc. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher.

ISBN: 978-0-07-180830-9
MHID: 0-07-180830-2

The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-174519-2, MHID: 0-07-174519-X.

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NOTE: Dr. Faucis work as editor and author was performed outside the scope of his employment as a U.S. government employee. This work represents his personal and professional views and not necessarily those of the U.S. government.

TERMS OF USE

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GERHARD P. BAUMANN, MD
Professor of Medicine Emeritus
Division of Endocrinology, Metabolism, and Molecular Medicine
Northwestern University Feinberg School of Medicine
Chicago, Illinois

S. ANDREW JOSEPHSON, MD
Assistant Professor of Neurology, Director, Neurohospitalist Program
University of California, San Francisco
San Francisco, California

CAROL A. LANGFORD, MD, MHS
Director, Center for Vasculitis Care and Research
Department of Rheumatic and Immunologic Diseases
Cleveland Clinic
Cleveland, Ohio

LEONARD S. LILLY, MD
Professor of Medicine
Harvard Medical School
Chief, Brigham and Womens/Faulkner Cardiology
Brigham and Womens Hospital
Boston, Massachusetts

DAVID B. MOUNT, MD Assistant Professor of Medicine
Harvard Medical School
Associate Physician, Renal Division, Brigham and Womens Hospital
Staff Physician, Renal Division, VA Boston Healthcare System
Boston, Massachusetts

EDWIN K. SILVERMAN, MD, PhD Associate Professor of Medicine
Chief, Channing Division of Network Medicine
Department of Medicine, Brigham and Womens Hospital
Harvard Medical School
Boston, Massachusetts

NEERAJ K. SURANA, MD, PhD
Instructor in Pediatrics
Harvard Medical School
Assistant in Medicine
Boston Childrens Hospital
Boston, Massachusetts

Numbers indicate the chapters written or co-written by the contributor.

GERHARD P. BAUMANN, MD
1, 3, 4, 7, 8, 24, 25, 30, 32, 35, 36, 127, 179190, 210, 213, 218, 220

ANTHONY S. FAUCI, MD
28, 33, 48, 49, 53, 65, 66, 114, 161178

STEPHEN L. HAUSER, MD
6, 1723, 5463, 84, 191209, 211, 212, 217

J. LARRY JAMESON, MD, PhD
1, 3, 4, 7, 8, 24, 25, 30, 32, 35, 36, 127, 179190, 210, 213, 218, 220

S. ANDREW JOSEPHSON, MD
6, 1723, 5463, 84, 191209, 211, 212, 217

DENNIS L. KASPER, MD
13, 26, 29, 31, 34, 64, 85113, 115118, 141, 154, 214

CAROL A. LANGFORD, MD
28, 33, 48, 49, 53, 65, 66, 114, 161178

LEONARD S. LILLY, MD
11, 12, 14, 37, 38, 40, 119126, 128136, 215

DAN L. LONGO, MD
9, 10, 27, 4347, 50, 51, 6783, 158160, 216

JOSEPH LOSCALZO, MD, PhD