Editorial Board
DAN L. LONGO, MD
Professor of Medicine, Harvard Medical School
Senior Physician, Brigham and Womens Hospital
Deputy Editor, New England Journal of Medicine
Boston, Massachusetts
ANTHONY S. FAUCI, MD
Chief, Laboratory of Immunoregulation
Director, National Institute of Allergy and Infectious Diseases
National Institutes of Health
Bethesda, Maryland
DENNIS L. KASPER, MD
William Ellery Channing Professor of Medicine
Professor of Microbiology and Molecular Genetics
Harvard Medical School
Director, Channing Laboratory
Department of Medicine, Brigham and Womens Hospital
Boston, Massachusetts
STEPHEN L. HAUSER, MD
Robert A. Fishman Distinguished Professor and Chairman
Department of Neurology, University of California
San Francisco, California
J. LARRY JAMESON, MD, PHD
Robert G. Dunlop Professor of Medicine
Dean, University of Pennsylvania School of Medicine
Executive Vice-President of the University of Pennsylvania for the Health System
Philadelphia, Pennsylvania
JOSEPH LOSCALZO, MD, PHD
Hersey Professor of the Theory and Practice of Medicine
Harvard Medical School
Chairman, Department of Medicine
Physician-in-Chief, Brigham and Womens Hospital
Boston, Massachusetts
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CONTENTS
PREFACE
This is the third edition of Harrisons Self-Assessment and Board Review that we have had the honor of working on. We thank the editors of the 18th edition of Harrisons Principles of Internal Medicine for their continued confidence in our ability to produce a worthwhile companion to their exceptional textbook. It is truly inspirational to remind ourselves why we love medicine broadly, and internal medicine specifically.
The care of patients is a privilege. As physicians, we owe it to our patients to be intelligent, contemporary, and curious. Continuing education takes many forms; many of us enjoy the intellectual stimulation and active learning challenge of the question-answer format. It is in that spirit that we offer the 18th edition of the Self-Assessment and Board Review to students, housestaff, and practitioners. We hope that from it you will learn, read, investigate, and question. The questions and answers are particularly conducive to collaboration and discussion with colleagues. This edition contains over 1100 questions that, whenever possible, utilize realistic patient scenarios including radiographic or pathologic images. Similarly, our answers attempt to explain the correct or best choice, often supported with figures from the 18th edition of
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