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Jacob Peer - Clinical Ophthalmic Oncology: Eyelid and Conjunctival Tumors

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Jacob Peer Clinical Ophthalmic Oncology: Eyelid and Conjunctival Tumors

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Written by internationally renowned experts, the 3rd edition of this six volume textbook provides detailed practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. Supplying the reader with state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible, this book is divided into six volumes: Basic Principles, Eyelid and Conjunctival Tumors, Orbital Tumors, Uveal Tumors, Retinal Tumors, and Retinoblastoma. The information presented enables readers to provide effective patient care using the latest knowledge on ophthalmic oncology and to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs from the authors private collections, histopathologic microphotographs, imaging studies, and crisp illustrations. Clinical Ophthalmic Oncologys clinically focused and user-friendly format allows for rapid retrieval of information in daily practice and is written for residents, fellows, and any physician involved in the care of patients with ocular or orbital malignancies. Additionally, this edition adds several hundred new images to improve comprehension of procedures and techniques. This volume provides the examination techniques, classification, and differential diagnosis of eyelid tumors and conjunctival and corneal tumors, carefully explained with treatment options considered in detail.

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Editors Jacob Peer Arun D Singh and Bertil E Damato Clinical Ophthalmic - photo 1
Editors
Jacob Peer , Arun D. Singh and Bertil E. Damato
Clinical Ophthalmic Oncology Eyelid and Conjunctival Tumors 3rd ed. 2019
Editors Jacob Peer Ocular Onocology Service and Ophthalmic Pathology - photo 2
Editors
Jacob Peer
Ocular Onocology Service and Ophthalmic Pathology Laboratory, Department of Ophthalmology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
Arun D. Singh
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA
Bertil E. Damato
Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
ISBN 978-3-030-06045-9 e-ISBN 978-3-030-06046-6
https://doi.org/10.1007/978-3-030-06046-6
Library of Congress Control Number: 2019933401
Springer Nature Switzerland AG 2019
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

Ophthalmic tumors are rare and diverse so that their diagnosis can be quite complex. Treatment usually requires special expertise and equipment and, in many instances, is controversial. The field is advancing rapidly, because of accelerating progress in tumor biology, pharmacology, and instrumentation. Increasingly, the care of patients with an ocular or adnexal tumor is provided by a multidisciplinary team, consisting of ocular oncologists, general oncologists, radiotherapists, pathologists, psychologists, and other specialists.

For all these reasons, we felt that there was a need for the new edition of the textbook providing a balanced view of current clinical practice. Although each section of Clinical Ophthalmic Oncology, 3rd Edition now represents a standalone volume, each chapter has a similar layout with boxes that highlight the key features, tables that provide comparison, and flow diagrams that outline therapeutic approaches.

The enormous task of editing a multi-author, multivolume textbook could not have been possible without the support and guidance by the staff at Springer: Caitlin Prim, Melanie Zerah, ArulRonika Pathinathan, and Karthik Rajasekar. Michael D. Sova kept the pressure to meet the production deadlines.

It is our sincere hope that our efforts will meet high expectation of the readers.

Jacob Peer
Bertil E. Damato
Arun D. Singh
Jerusalem, Israel Oxford, UK Cleveland, OH, USA
Acknowledgments

To my wife, Edith, and my children, Liron, Neta, and Doron, for years of support and patience.

Jacob Peer, MD

To my family, Frankanne, Erika, Stephen, and Anna.

Bertil E. Damato, MD, PhD, FRCOphth

To my parents who educated me beyond their means, my wife, Annapurna, and my children, Nakul and Rahul, who make all my efforts worthwhile.

Arun D. Singh, MD

Contents
Catherine J. Hwang and Julian D. Perry
Jacob Peer and Shahar Frenkel
Lynn Schoenfield and Arun D. Singh
Mordechai Rosner and Ido Didi Fabian
Mordechai Rosner and Ido Didi Fabian
Mordechai Rosner and Ido Didi Fabian
Jacob Peer and Robert Folberg
Martina C. Herwig-Carl and Karin U. Loeffler
Geeta K. Vemuganti and Santosh G. Honavar
Andrew J. Rong , Jennifer I. Hui and David T. Tse
Matteo Scaramuzzi , Lucy T. Xu , Arun D. Singh and Elias I. Traboulsi
Jacob Peer and Shahar Frenkel
Jacob Peer and Shahar Frenkel
Jacob Peer and Shahar Frenkel
Jacob Peer , Shahar Frenkel and Arun D. Singh
Jacob Peer and Robert Folberg
Jacob Peer and Robert Folberg
Jacob Peer and Shahar Frenkel
Hans E. Grossniklaus , Daniel R. Capiz-Correa and Jill R. Wells
Ghada Al Bayyat , Dan Arreaza-Kaufman , Anat Galor , Jacob Peer and Carol L. Karp
Oded Sagiv and Bita Esmaeli
Anat Galor , Bennie H. Jeng , Arun D. Singh and Carol L. Karp
Christopher Fleming , Shlomo Koyfman and Arun D. Singh
Matteo Scaramuzzi , Lucy T. Xu , Arun D. Singh and Elias I. Traboulsi
Contributors
Ghada Al Bayyat MD
Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, FL, USA
Dan Arreaza MD
Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, FL, USA
Daniel R. Capiz-Correa MD
Department of Orbit and Oculoplastic, Fundacion Hospital Nuestra Senora de la Luz, I.A.P., Mexico City, Mexico
Bertil E. Damato MD, PhD, FRCOphth
Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
Bita Esmaeli MD, MA
Department of Plastic Surgery, Orbital Oncology and Ophthalmic Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Ido Didi Fabian MD
Department of Ophthalmology, Ocular Oncology Center, Goldschleger Eye Institute, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Christopher Fleming MD
Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH, USA
Robert Folberg MD
Oakland University William Beaumont School of Medicine, Rochester, MI, USA
Shahar Frenkel MD, PhD
Ocular Oncology Service and Ophthalmic Pathology Laboratory, Department of Ophthalmology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
Anat Galor MD
Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, FL, USA
Hans E. Grossniklaus MD MBA
Department of Ophthalmology, Emory University School of Medicine/Emory Eye Center, Atlanta, GA, USA
Martina C. Herwig-Carl MD, FEBO
Department of Ophthalmology, University Clinic Bonn, Bonn, NRW, Germany
Santosh G. Honavar MD, FACS
Department of Ophthalmic Plastic Surgery and Ocular Oncology, Centre for Sight, Hyderabad, Telangana, India
Jennifer I. Hui MD
Oculofacial Plastic Surgery, The Eyelid Institute, Palm Desert, CA, USA
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