Kahook Malik Y. - Chandler and Grants Glaucoma

Cover images reprinted with permission from Massachusetts Eye and Ear, Abraham Pollen Archives.

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Library of Congress Cataloging-in-Publication Data

Names: Kahook, Malik Y., editor. | Schuman, Joel S., editor.

Title: Chandler and Grants glaucoma / editors, Malik Y. Kahook, Joel S. Schuman.

Other titles: Glaucoma

Description: Sixth edition. | Thorofare, NJ : SLACK Incorporated, [2021] | Includes bibliographical references and index.

Identifiers: LCCN 2020033175 (print) | LCCN 2020033176 (ebook) | ISBN 9781630914653 (hardcover) | ISBN 9781630914660 (epub) | ISBN 9781630914677 (other)

Subjects: MESH: Glaucoma

Classification: LCC RE871 (print) | LCC RE871 (ebook) | NLM WW 290 | DDC 617.7/41--dc23

LC record available at https://lccn.loc.gov/2020033175

LC ebook record available at https://lccn.loc.gov/2020033176

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We dedicate this textbook to our families for their constant support, our residents and fellows for allowing us the privilege of passing on the teachings of Drs. Chandler and Grant, and our patients for the honor of being entrusted with their care. We are grateful to our mentors, W. Morton Grant, MD and David L. Epstein, MD for their insights, lessons, friendship and wisdom. In particular, we thank Dave for his advice and constant encouragement during our work on Chandler and Grants Glaucoma, and for trusting us with the responsibility of carrying on the writing and editing of this book.

Malik Y. Kahook, MD is Professor of Ophthalmology and The Slater Family Endowed Chair in Ophthalmology at the University of Colorado School of Medicine. He is Vice Chair of Translational Research and serves as chief of the glaucoma service and co-director of the glaucoma fellowship at the UCHealth Sue Anschutz-Rodgers Eye Center.

Dr. Kahook has authored more than 400 peer-reviewed manuscripts, abstracts, and book chapters and is editor of Essentials of Glaucoma Surgery; MIGS: Advances in Glaucoma Surgery; and the seminal textbook of glaucoma Chandler and Grants Glaucoma. He is Editor-in-Chief of the open access wiki-based glaucoma educational platform Kahooks Essentials of Glaucoma Therapy (www.KEOGT.com). Dr. Kahook has received funding from the National Eye Institute, Foundations and Industry over the past 14 years. He was awarded an American Glaucoma Society Clinician-Scientist Fellowship Award in 2007 as well as the American Glaucoma Society Compliance Grant in 2006 and was named New Inventor of the Year for the University of Colorado in 2009 and Inventor of the Year for 2010. He received the American Glaucoma Society Innovator Award (2020), the American Academy of Ophthalmology Achievement Award in 2011, the American Academy of Ophthalmology Senior Achievement Award in 2017, the American Academy of Ophthalmology Secretariat Award (2014), the Ludwig Von Sallmann Clinician-Scientist Award (ARVO) in 2013 and was ranked second on the 40 under 40 Ophthalmology Power List (2015). Dr. Kahook has served on several editorial boards including the American Journal of Ophthalmology and International Glaucoma Review. He is an active volunteer with Orbis and has been a consultant to the US Food and Drug Administrations Ophthalmic Device Division since 2008.

Dr. Kahook has been active in both basic and clinical research. He and his colleagues were among the first to report the use of antivascular endothelial growth factor (VEGF) agents for treating neovascular glaucoma, as well as the first to report the use of these agents to modulate blebs after filtration surgery. Dr. Kahook and colleagues explored the effects of anti-VEGF agents on the trabecular meshwork and published a series of papers that explored the potential for intraocular pressure spikes from contaminants in compounded anti-VEGF syringes. His work exploring silicone microbubbles in repackaged bevacizumab shed light on several compounding pharmacy practices, including shipping techniques and freeze thaw cycles that resulted in recommendations to decrease the chance of these potentially harmful contaminants from reaching the patient. Dr. Kahook is widely published in areas ranging from the effects of medication preservatives on the ocular surface to novel imaging techniques with femtosecond lasers, as well as 24-hour intraocular pressure fluctuations and exploration of adherence to medical therapy. His first report with Dr. Robert Noecker on the use of fibrin glue for glaucoma drainage device surgery has been adopted by surgeons globally.

Dr. Kahooks translational research accomplishments have focused on multiple unmet needs, including advanced cataract surgery devices and implants, novel glaucoma therapies, and advanced imaging techniques. He has filed for more than 120 patents with more than 40 patents granted to date. Several of Dr. Kahooks patents have been licensed by companies including Johnson & Johnson Vision, New World Medical, ShapeTech, Alcon, ClarVista Medical, and SpyGlass Ophthalmics for development and commercialization. Six of his devices are currently in human trials or commercialized for clinical use. ClarVista Medical, acquired by Alcon in 2017, developed an advanced intraocular lens technology platform invented by Dr. Kahook. He is also inventor of the Kahook Dual Blade, which is marketed globally by New World Medical. Dr. Kahook is also inventor of the VERUS Capsulorhexis Device, commercialized by MileHigh Ophthalmics, and the ShapeTech shape memory polymer intraocular lens material, which is licensed by Johnson & Johnson Vision. His inventions have raised more than $100 million for development and commercialization since 2008 and have been used to treat more than 100 thousand patients globally since 2012.