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2014 Mayo Foundation for Medical Education and Research (MFMER)
ISBN-10: 0-8487-4388-1
ISBN-13: 978-0-8487-4388-8
Library of Congress Control Number: 2014946271
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MAYO CLINIC
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Joseph A. Murray, M.D.
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Imad Absah, M.D.
Rachel A. H. Bartony
Alicia C. Bartz
Julie A. Buchholtz, L.D.
Manish J. Gandhi, M.D.
Kevin G. Kaufman
Vandana Nehra, M.D.
Jennifer K. Nelson, RDN, L.D.
Miguel A. Park, M.D.
John A. Schaffner, M.D.
Richard J. Seime, Ph.D., L.P.
Melissa R. Snyder, Ph.D.
Suzanne P. Sobotka
Maria I. Vazquez Roque, M.D.
Laura Hamilton Waxman
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Special thanks to Greg A. Amason,
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Vanessa Wu
Cover design by Christopher Rhoads
PREFACE
My journey with celiac disease started in Galway in the West of Ireland, where celiac disease was remarkably common in the 1960s and 70s. My alma mater, the National University of Ireland in Galway, became a center for celiac disease research. As a medical student and intern, I regarded celiac disease as part of the medical landscape; it seemed to be as commonplace as hypertension or heart disease. It left me with the impression that celiac disease was far more common than perhaps was known at the time. My journey with celiac disease continued in Dublin, and I can vividly recall the last patient that I diagnosed before leaving Ireland to come to America. It was a young woman who had few, if any, gastrointestinal symptoms. I also recall my mentor telling me that this would likely be the last patient with celiac disease I would see because the disease was rare in the United States.
My move across the Atlantic wasnt to follow celiac disease but to pursue my interest in other gastrointestinal disorders. But in the Iowa cornfields, I discovered celiac disease. Its rare that a single patient can so influence a career, but at The University of Iowa I met a woman who broke the mold for how celiac disease was supposed to act. She was overweight not underweight, had constipation not diarrhea, lost weight on a gluten-free diet and gained weight when she ate gluten.