Hannah Batchelor (editor) - Biopharmaceutics: From Fundamentals to Industrial Practice (Advances in Pharmaceutical Technology)

1. Chapter 3
2. Chapter 4
3. Chapter 5
4. Chapter 6
5. Chapter 7
6. Chapter 8
7. Chapter 10
8. Chapter 11
9. Chapter 12
10. Chapter 13
11. Chapter 15
12. Chapter 17

1. Chapter 1
2. Chapter 2
3. Chapter 3
4. Chapter 4
5. Chapter 5
6. Chapter 6
7. Chapter 7
8. Chapter 8
9. Chapter 9
10. Chapter 10
11. Chapter 11
12. Chapter 12
13. Chapter 13
14. Chapter 14
15. Chapter 15
16. Chapter 16
17. Chapter 17

ADVANCES IN PHARMACEUTICAL TECHNOLOGY

A Wiley Book Series

Series Editors:
Dennis Douroumis, University of Greenwich, UK
Alfred Fahr, FriedrichSchiller University of Jena, Germany
Jurgen Siepmann, University of Lille, France
Martin Snowden, University of Greenwich, UK
Vladimir Torchilin, Northeastern University, USA

Titles in the Series

HotMelt Extrusion: Pharmaceutical Applications
Edited by Dionysios Douroumis

Drug Delivery Strategies for Poorly WaterSoluble Drugs
Edited by Dionysios Douroumis and Alfred Fahr

Computational Pharmaceutics: Application of Molecular Modeling in Drug Delivery
Edited by Defang Ouyang and Sean C. Smith

Pulmonary Drug Delivery: Advances and Challenges
Edited by Ali Nokhodchi and Gary P. Martin

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
Edited by Ryan Donnelly and Raj Singh

Drug Delivery Systems for Tuberculosis Prevention and Treatment
Edited by Anthony J. Hickey

Continuous Manufacturing of Pharmaceuticals
Edited by Peter Kleinebudde, Johannes Khinast, and Jukka Rantanen

Pharmaceutical Quality by Design
Edited by Walkiria S Schlindwein and Mark Gibson

In VitroDrug Release Testing of Special Dosage Forms
Edited by Nikoletta Fotaki and Sandra Klein

Characterization of Pharmaceutical Nano and Microsystems
Edited by Leena Peltonen

Biopharmaceutics: From Fundamentals to Industrial Practice
Edited by Hannah Batchelor

Forthcoming Titles:

Process Analytics for Pharmaceuticals
Edited by Jukka Rantanen, Clare Strachan and Thomas De Beer

Mucosal Drug Delivery
Edited by Rene Holm

Edited by

HANNAH BATCHELOR

Strathclyde Institute of Pharmacy and Biomedical Sciences

University of Strathclyde Glasgow, United Kingdom

This edition first published 2022
2022 John Wiley & Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Hannah Batchelor to be identified as the author of the editorial material in this work has been asserted in accordance with law.

Registered Office(s)
John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK

Editorial Office
Boschstr. 12, 69469 Weinheim, Germany

For details of our global editorial offices, customer services, and more information about Wiley products visit us at www.wiley.com.

Wiley also publishes its books in a variety of electronic formats and by printondemand. Some content that appears in standard print versions of this book may not be available in other formats.

Limit of Liability/Disclaimer of Warranty
In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of experimental reagents, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each chemical, piece of equipment, reagent, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress CataloginginPublication Data

Names: Batchelor, Hannah, editor.
Title: Biopharmaceutics : from fundamentals to industrial practice / edited by Hannah Batchelor.
Other titles: Biopharmaceutics (Batchelor) | Advances in pharmaceutical technology.
Description: First edition. | Chichester, UK ; Hoboken, NJ : John Wiley & Sons, 2022. | Series: Advances in pharmaceutical technology | Includes bibliographical references and index.
Identifiers: LCCN 2021050446 (print) | LCCN 2021050447 (ebook) | ISBN 9781119678281 (cloth) | ISBN 9781119678274 (adobe pdf) | ISBN 9781119678373 (epub)
Subjects: MESH: Biopharmaceuticsmethods | Drug Design
Classification: LCC RM301.5 (print) | LCC RM301.5 (ebook) | NLM QV 35 | DDC 615.7dc23/eng/20211101
LC record available at https://lccn.loc.gov/2021050446
LC ebook record available at https://lccn.loc.gov/2021050447

Cover Design: Wiley
Cover Image: SCIEPRO/Getty Images

Precious AkhuemokhanInstitute of Pharmaceutical Sciences, Kings College London, London, United Kingdom

Abdul W. BasitDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, London, United Kingdom

Hannah BatchelorStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

Shanoo BudhdeoSeda Pharmaceutical Development Services, Alderley Edge, Alderley Park, Cheshire, United Kingdom

James ButlerBiopharmaceutics, Product Development and Supply, GlaxoSmithKline R&D, Ware, United Kingdom

Paul A. DickinsonSeda Pharmaceutical Development Services, Alderley Edge, Alderley Park, Cheshire, United Kingdom