Peter J. Delves
Professor Delves obtained his PhD from the University of London in 1986 and is a Professor of Immunology at UCL (University College London). His research has focused on molecular aspects of antigen recognition. He has authored and edited a number of immunology books, and teaches the subject at a broad range of levels.
Seamus J. Martin
Professor Martin received his PhD from The National University of Ireland in 1990 and trained as a post-doctoral fellow at University College London (with Ivan Roitt) and The La Jolla Institute for Allergy and Immunology, California, USA (with Doug Green). Since 1999, he is the holder of the Smurfit Chair of Medical Genetics at Trinity College Dublin and is also a Science Foundation Ireland Principal Investigator. His research is focused on various aspects of programmed cell death (apoptosis) in the immune system and in cancer and he has received several awards for his work in this area. He has previously edited two books on apoptosis and was elected as a Member of The Royal Irish Academy in 2006 and as a member of The European Molecular Biology Organisation (EMBO) in 2009.
Dennis R. Burton
Professor Burton obtained his BA in Chemistry from the University of Oxford in 1974 and his PhD in Physical Biochemistry from the University of Lund in Sweden in 1978. After a period at the University of Sheffield, he moved to the Scripps Research Institute in La Jolla, California in 1989 where he is Professor of Immunology and Molecular Biology. His research interests include antibodies, antibody responses to pathogens and vaccine design, particularly in relation to HIV.
Ivan M. Roitt
Professor Roitt was born in 1927 and educated at King Edwards School, Birmingham and Balliol College, Oxford. In 1956, together with Deborah Doniach and Peter Campbell, he made the classic discovery of thyroglobulin autoantibodies in Hashimotos thyroiditis which helped to open the whole concept of a relationship between autoimmunity and human disease. The work was extended to an intensive study of autoimmune phenomena in pernicious anaemia and primary biliary cirrhosis. In 1983 he was elected a Fellow of The Royal Society, and has been elected to Honorary Membership of the Royal College of Physicians and appointed Honorary Fellow of The Royal Society of Medicine.
This edition first published 2011 1971, 1974, 1977, 1980, 1984, 1988, 1991, 1994, 1997, 2001, 2006 by Peter J Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt
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Library of Congress Cataloging-in-Publication Data
Roitts essential immunology / Peter J. Delves... [et al.]. 12th ed.
p. cm. (Essentials ; 16)
Rev. ed. of: Roitts essential immunology / Ivan M. Roitt, Peter J. Delves.
Includes bibliographical references and index.
ISBN 978-1-4051-9683-3 (pbk.)
1. Immunology. I. Delves, Peter J. II. Roitt, Ivan M. (Ivan Maurice) Roitts essential immunology. III. Title: Essential immunology.
QR181.R57 2011
616.079-dc22
2010047392
Acknowledgments
Thie input of the editorial team of Elizabeth Johnston, Laura Murphy and Cathryn Gates at Wiley-Blackwell and the project management of Ruth Swan is warmly acknowledged. We are much indebted to the co-editors of Immunology, J. Brostoff, D. Roth and D. Male, together with the publishers, Mosby, and the following individuals for permission to utilize or modify their figures: