Marshal Shlafer - Pharmacology PreTest Self-Assessment and Review, 14th edition

Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.

Copyright 2013 by McGraw-Hill Education, LLC. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher.

ISBN: 978-0-07-179147-2
MHID: 0-07-179147-7

The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-179146-5, MHID: 0-07-179146-9.

All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every occurrence of a trademarked name, we use names in an editorial fashion only, and to the benefit of the trademark owner, with no intention of infringement of the trademark. Where such designations appear in this book, they have been printed with initial caps.

McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales promotions, or for use in corporate training programs. To contact a representative please e-mail us at bulksales@mcgraw-hill.com.

PreTest is a trademark of McGraw-Hill Education LLC.

TERMS OF USE

This is a copyrighted work and McGraw-Hill Education and its licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Educations prior consent. You may use the work for your own noncommercial and personal use; any other use of the work is strictly prohibited. Your right to use the work may be terminated if you fail to comply with these terms.

THE WORK IS PROVIDED AS IS. McGRAW-HILL EDUCATION AND ITS LICENSORS MAKE NO GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill Education and its licensors do not warrant or guarantee that the functions contained in the work will meet your requirements or that its operation will be uninterrupted or error free. Neither McGraw-Hill Education nor its licensors shall be liable to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for any damages resulting therefrom. McGraw-Hill Education has no responsibility for the content of any information accessed through the work. Under no circumstances shall McGraw-Hill Education and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise.

David Jonathan Kadouri

University of Medicine and Health SciencesSt. Kitts

Medical Student

Class of 2013

Matthew Klairmont

Rush Medical College

Medical Student

Class of 2013

Nikul Patel, MD

University of Medicine and Dentistry of New Jersey

School of Medicine

Welcome to this, the 14th edition, of Pharmacology: PreTestSelf-Assessment and Review. Im pleased to have been invited back to write this edition after doing the previous three. Whether youre studying for Step 1 of the USMLE, or for a course exam that includes pharmacology content, I think youll find this helpful.

I believe this PreTestSelf-Assessment and Review will help you evaluate and review your intensive and extensive knowledge of pharmacology and therapeuticsyour knowledge of basic facts and principles, and your ability to apply that knowledge to some common clinical situations.

Among the changes here youll find in 14/e for pharmacology are:

Many new or extensively revised questions, most based on clinical vignettes or scenarios, most already tested on hundreds of first- and second-year medical students, and all but a select few in a format youll likely see on Step 1. Many changes were necessitated by the approval of new drugs that you need to know about in some way. Many were made in response to excellent comments from medical student and house officer reviewers.

More integration of content between the various areas of pharmacology and therapeutics, with many questions that encourage you to integrate new material with content presented earlier.

A better blend of questions that integrate basic pharmacology content with basic information from other preclinical disciplines.

Clearer and more complete explanations for why correct answers are correct, and the others are not.

Updated cross-references to the latest editions of two widely used pharmacology texts, in the answers, so you can find additional information or explanations if you wish.

An updated resource that lets you look at suffixes of generic drug names and deduce with reasonable (or better) certainty the chemical or pharmacologic group or class to which a drug belongs.

Even though your profs may tell you otherwise, pharmacology is pure memorization the ultimate challenge in medical memorization some remedy to dull the pain of the subject is needed.

That was the admonition to students in a popular exam study aid.

Baloney, I say. Being a realist, there may be some truth to that. But, read on, and youll see why I dont think thats an absolute truth, and certainly isnt the best way to learn pharmacology.