Cover
title | : | Peptide Nucleic Acids : Protocols and Applications 2Nd Ed. / |
author | : | Nielsen, Peter E. |
publisher | : | Taylor & Francis Routledge |
isbn10 | asin | : | 0954523245 |
print isbn13 | : | 9780954523244 |
ebook isbn13 | : | 9780203508558 |
language | : | English |
subject | Nucleic acids, Peptide Nucleic Acids--Laboratory Manuals. |
publication date | : | 2004 |
lcc | : | QD431.P47 2004eb |
ddc | : | 572.8 |
subject | : | Nucleic acids, Peptide Nucleic Acids--Laboratory Manuals. |
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Page i
PEPTIDE NUCLEIC ACIDS
Protocols and Applications
Second Edition
Edited by
Peter E.Nielsen
The Panum Institute, Copenhagen
horizon bioscience
Page ii
This edition published in the Taylor & Francis e-Library, 2005.
To purchase your own copy of this or any of Taylor & Francis or Routledges collection of thousands of eBooks please go to www.eBookstore.tandf.co.uk.
Copyright 2004
Horizon Bioscience
32 Hewitts Lane
Wymondham
Norfolk NR 18 0JA
U.K.
www.horizonbioscience.com
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
ISBN 0-203-50855-6 Master e-book ISBN
ISBN 0-203-61705-3 (OEB Format)
ISBN: 0-9545232-4-5 (Print Edition)
Description or mention of instrumentation, software, or other products in this book
does not imply endorsement by the author or publisher. The author and publisher do
not assume responsibility for the validity of any products or procedures mentioned
or described in this book or for the consequences of their use.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval
system, or transmitted, in any form or by any means, electronic, mechanical,
photocopying, recording or otherwise, without the prior permission of the publisher.
No claim to original U.S. Government works.
Page iii
Contents
Contents | iii |
Contributors | v |
Preface | vii |
Chapter 1 | An Introduction to PNA Peter E.NielsenandMichael Egholm | |
Chapter 2 | PNA Synthesis by Boc Chemistry Troels Koch | |
Chapter 3 | Synthesis of PNA Oligomers by Fmoc Chemistry Ralph Casale,Ivar S.JensenandMichael Egholm | |
Chapter 4 | Thermodynamics of PNA Interactions Tommi Ratilainen,Anders HolmnandBengt Nordn | |
Chapter 5 | Peptide Nucleic Acid Targeting of Double-Stranded DNA Thomas Bentin,H.Jakob LarsenandPeter E.Nielsen | |
Chapter 6 | PNA Beacons and Fluoroprobes Bhaskar Datta,Miaomiao WangandBruce A.Armitage | |
Chapter 7 | Vector Tagging via PNA Alex G.Rebuffat,Alessio G.BernasconiandBrigitte M.Frey | |
Chapter 8 | PCR Clamping Henrik rum | |
Chapter 9 | PNA Directed Genome Rare Cutting: New Developments Maxim D.Frank-KamenetskiiandVadim V.Demidov | |
Page iv
Chapter 10 | PNA Openers for Duplex DNA: Basic Facts, Fine Tuning and Emerging Applications Vadim V.Demidov | |
Chapter 11 | Combined Use of PNA and DNA for Fluorescence In Situ Hybridization (FISH) Kirsten Vang Nielsen,Sven Mller,Tim Svenstrup Poulsen,Susanne GabsandAndreas Schnau | |
Chapter 12 | Production of PNA-Arrays for Nucleic Acid Detection Anette Jacob,Ole Brandt,Simone Wrtz,Achim Stephan,Martina SchnlzerandJrg D.Hoheisel | |
Chapter 13 | Antisense in Eukaryotic Systems David R.Corey | |
Chapter 14 | Antisense Effects in Escherichia coli Liam Good,Rikard DryseliusandPeter E.Nielsen | |
Appendix | |
Index | |
Page v
Contributors
Bruce A.Armitage
Department of Chemistry
Carnegie Mellon University
4400 Fifth Avenue
Pittsburgh PA 152133890, USA
army@cyrus.andrew.cmu.edu
Thomas Bentin
Center for Biomolecular Recognition
Institute for Medical Biochemistry and Genetics, Dept. B
University of Copenhagen
The Panum Institute
Blegdamsvej 3c
DK-2200 N Copenhagen, Denmark
Alessio G.Bernasconi
Division of Nephrology and Hypertension
Departement of Clinical Research
University of Berne
Freiburgstrasse
CH-3010 Inselspital Berne, Switzerland
Ole Brandt
Deutsches Krebsforschungszentrum
Im Neuenheimer Feld 580
D-69120 Heidelberg, Germany
o.brandt@dkfz.de
Ralph Casale
Applied Biosystems
15 DeAngelo Drive
Bedford MA 01730, USA
CasaleRA@appliedbiosystems.com
David R.Corey
Departments of Pharmacology and Biochemistry
University of Texas Southwestern Medical
Center at Dallas
5323 Harry Hines Blvd.
Dallas TX 753909041, USA
david.corey@utsouthwestern.edu
Bhaskar Datta
Department of Chemistry
Carnegie Mellon University
4400 Fifth Avenue
Pittsburgh PA 152133890, USA
Vadim V.Demidov
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