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DAMS - LAST LOOK: Microbiology

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DAMS LAST LOOK: Microbiology
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    LAST LOOK: Microbiology
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    Delhi Academy of Medical Sciences (P) Ltd.
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LAST LOOK

Microbiology

LAST LOOK Microbiology Largest Medical Education Institute in the - photo 1

LAST LOOK

Microbiology

Largest Medical Education Institute in the Country Published by Delhi - photo 2

Largest Medical Education Institute in the Country

Published by Delhi Academy of Medical Sciences P Ltd HEAD OFFICE Delhi - photo 3

Published by Delhi Academy of Medical Sciences (P) Ltd.

HEAD OFFICE

Delhi Academy of Medical Sciences (P.) Ltd.

4-B, Grovers Chamber, Pusa Road,

Near Karol Bagh Metro Station,

New Delhi-110 005 Phone : 011-4009 4009
http://www.damsdelhi.com Email: info@damsdelhi.com

ISBN :

First Published 1999, Delhi Academy of Medical Sciences 2018 DAMS Publication

All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic, mechanical, including photocopying, recording, or any information storage and retrieval system without permission, in writing, from the author and the publishers.

This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission. Reasonable efforts have been made to publish reliable data and information, but the authors and the publishers cannot assume responsibility for the validity of all materials. Neither the authors nor the publishers, nor anyone else associated with this publication, shall be liable for any loss, damage or liability directly or indirectly caused or alleged to be caused by this book.

Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming and recording, or by any information storage or retrieval system, without permission in writing from Delhi Academy of Medical Sciences. The consent of Delhi Academy of Medical Sciences does not extend to copying for general distribution, for promotion, for creating new works, or for resale. Specific permission must be obtained in writing from Delhi Academy of Medical Sciences for such copying.

Trademark notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation, without intent to infringe.

Typeset by Delhi Academy of Medical Sciences Pvt. Ltd., New Delhi (India).


The agents of human infectious diseases are bacteria, fungi (yeasts and molds), protozoa, helminths (worms), and viruses. Bacterial cells have a prokaryotic nucleus, whereas human, fungal, protozoan, and helminth cells have a eukaryotic nucleus. Viruses are not cells and do not have a nucleus.

All cells contain both DNA and RNA, whereas viruses contain either DNA or RNA, but not both.

Bacterial and fungal cells are surrounded by a rigid cell wall, whereas human, protozoan, and helminth cells have a flexible cell membrane.

The bacterial cell wall contains peptidoglycan, whereas the fungal cell wall contains chitin.

Comparison of Conjugation, Transduction, and Transformation

Transfer

Procedure

Process

Type of Cells Involved

Nature of DNA Transferred

Conjugation

DNA transferred from one bacterium to another

Prokaryotic

Chromosomal or plasmid

Transduction

DNA transferred by a virus from one cell to another

Prokaryotic

Any gene in generalized transduction; only certain genes in specialized transduction

Transformation

Purified DNA taken up by a cell

Prokaryotic or eukaryotic (e.g. human)

Any DNA

Members of the Normal Flora

Anatomic Location

Bacteroides species

Colon, throat, vagina

Candida albicans

Mouth, colon, vagina

Clostridium species

Colon

Corynebacterium species (diphtheroids)

Nasopharynx, skin, vagina

Enterococcus faecalis

Colon

Escherichia coli and other coliforms

Colon, vagina, outer urethra

Gardnerella vaginalis

Vagina

Haemophilus species

Nasopharynx, conjunctiva

Lactobacillus species

Mouth, colon, vagina

Neisseria species

Mouth, nasopharynx

Propionibacterium acnes

Skin

Pseudomonas aeruginosa

Colon, skin

Staphylococcus aureus

Nose, skin

Staphylococcus epidermidis

Skin, nose, mouth, vagina, urethra

Viridans streptococci

Mouth, nasopharynx

Bacterial diseases transmitted by insects:

Bacterium

Insect

Reservoir

Disease

Gram negative rods

Yersinia pestis

Rat fleas

Rodents (e.g. rats and prairie dogs)

Plague

Francisella

tularensis

Ticks

(Dermacentor)

Many animals (e.g. rabbits)

Tularemia

Spirochaetes

Borrelia

burgdorferi

Ticks (brodes)

Mice

Lyme disease

Borrelia

recurrentis

Lice

Humans

Relapsing fever

Rickettsiae

Rickettsia

rickettsii

Ticks

(Demacentor)

Dogs, rodents, and ticks (Dermacentor)

Rocky Mountain spotted fever

Rickettsia

prowazekii

Lice

Humans

Epidemic typhus

Ehrlichia

chaffeensis

Ticks

(Dermacentor,

brodes)

Dogs

Ehrilichiosis

Virulence Factors:

Organism

Virulence factors

Used in Vaccine

Comments

Gram-positive cocci

Streptococcus

pneumoniae

Polysaccharide

capsule

Yes

Determines

serotype

Streptococcus

pyogenes

M protein

No

Determines

serotype1

Streptococcus

aureus

Protein A

No

Binds to Fc region of IgG, which prevents activation of complement

Gram-negative cocci

Neisseria

meningitidis

Polysaccharide

capsule

Yes

Determines

serotype

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