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Preface
The first edition of this book provided undergraduate veterinary students with a brief introduction to veterinary microbiology and diseases caused by pathogenic microorganisms. Since its publication in 2003, there have been many changes in veterinary microbiology, some related to the classification of pathogenic microorganisms and others associated with the increased understanding of the pathogenesis of infectious diseases. Developments in molecular aspects of microbiology have broadened the scope of diagnostic methods and have improved our understanding of the epidemiological characteristics of many infectious diseases. New developments relating to the emergence of antibacterial resistance are of particular importance in veterinary therapeutics and in public health.
The second edition of this book includes new chapters on bacterial genetics, antibacterial resistance, immunology, antifungal chemotherapy, biosecurity and vaccination. Topics of particular importance in veterinary medicine are given extended coverage. Important changes which have occurred in veterinary microbiology in recent years are presented in relevant chapters. There are five sections in this book and the Appendix includes a list of relevant websites to facilitate readers requiring additional information on topics referred to in the book. Colour has been used to enhance the quality of the illustrations and to facilitate interpretation of complex diagrams.
Acknowledgements
We wish to acknowledge the assistance provided by colleagues who reviewed chapters, provided scientific, technical and editorial advice or who assisted in other ways: James Buckley, Rory Breathnach, Louise Britton, Jill Bryan, Marguerite Clyne, Hubert Fuller, James Gibbons, Stephen Gordon, Laura Luque-Sastre, Aidan Kelly, Pamela Kelly, Dores Maguire, Marta Martins, Kerri Malone, Jarlath Nally, David Quinn, Michael Quinn, Eoin Ryan, John Ryan, Patrick Raleigh, Shabarinath Srikumar, Graham Tynan, Patrick Wall and Annetta Zintl.
The facilities and support provided by the librarian, Carmel Norris and staff at the Veterinary Library are acknowledged with gratitude. We are grateful to Justinia Wood, Catriona Cooper and their colleagues at Wiley for the help and advice provided during the preparation of the book.
Dublin, January 2015
Abbreviations and definitions
AGID
agar gel immunodiffusion
ATP
adenosine triphosphate
BCG
bacille CalmetteGurin
bp
base pairs
cAMP
cyclic adenosine monophosphate
CD
cluster of differentiation
CFT
complement fixation test
CNS
central nervous system
cELISA
competitive enzyme-linked immunosorbent assay
DNA
deoxyribonucleic acid
ELISA
enzyme-linked immunosorbent assay
EU
European Union
FA
fluorescent antibody
Fc
crystallizable fragment, portion of an immunoglobulin without an antigen combining site
IFA
indirect fluorescent antibody
IFN
interferon
Ig
immunoglobulin
LPS
lipopolysaccharide
KOH
potassium hydroxide
MBC
minimal bactericidal concentration
MHC
major histocompatibility complex
MIC
minimal inhibitory concentration
MLST
multi-locus sequence typing
mRNA
messenger RNA
MRSA
methicillin-resistant Staphylococcus aureus
MZN
modified ZiehlNeelsen
nm
nanometre, 109 metre
NK cells
natural killer cells
OIE
Office International des pizooties (World Organization for Animal Health)
ORF
open reading frame
PAS
periodic acidSchiff
PCR
polymerase chain reaction
PFGE
pulsed-field gel electrophoresis
RFLP
restriction fragment length polymorphism
RNA
ribonucleic acid
rRNA
ribosomal RNA
RT-PCR
reverse transcriptase-polymerase chain reaction
RTX
repeats-in-toxin
SMEDI
stillbirth, mummification, embryonic death, infertility
V factor
nicotinamide adenine dinucleotide
VP
viral protein
UK
United Kingdom
m
micrometre or micron, 106 metre
USA
United States of America
UV light
ultraviolet light
X factor
haemin
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