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Cristina Stasi (editor) - The Complex Interplay Between Gut-Brain, Gut-Liver, and Liver-Brain Axes

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The Complex Interplay Between Gut-Brain, Gut-Liver, and Liver-Brain Axes: summary, description and annotation

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The Complex Interplay Between GutBrain, GutLiver, and LiverBrain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gutbrain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gutliver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liverbrain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome.

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Table of Contents List of tables Tables in Chapter 2 Tables in Chapter 4 - photo 1
Table of Contents
List of tables
  1. Tables in Chapter 2
  2. Tables in Chapter 4
  3. Tables in Chapter 5
  4. Tables in Chapter 8
  5. Tables in Chapter 9
List of illustrations
  1. Figures in Chapter 1
  2. Figures in Chapter 2
  3. Figures in Chapter 4
  4. Figures in Chapter 5
  5. Figures in Chapter 7
  6. Figures in Chapter 8
  7. Figures in Chapter 9
  8. Figures in Chapter 10
Landmarks
Table of Contents
The Complex Interplay Between GutBrain, GutLiver, and LiverBrain Axes

Edited by

Cristina Stasi

MASVE Interdepartmental Hepatology Center, Department of Experimental and Clinical Medicine, University of Florence and CRIA-MASVE Center for Research and Innovation, Careggi University Hospital, Florence, Italy

Epidemiology Unit, Regional Health Agency of Tuscany, Florence, Italy

Copyright Academic Press is an imprint of Elsevier 125 London Wall London EC2Y - photo 2

Copyright

Academic Press is an imprint of Elsevier

125 London Wall, London EC2Y 5AS, United Kingdom

525 B Street, Suite 1650, San Diego, CA 92101, United States

50 Hampshire Street, 5th Floor, Cambridge, MA 02139, United States

The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, United Kingdom

Copyright 2021 Elsevier Inc. All rights reserved.

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publishers permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notices

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.

To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

British Library Cataloguing-in-Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Cataloging-in-Publication Data

A catalog record for this book is available from the Library of Congress

ISBN: 978-0-12-821927-0

For Information on all Academic Press publications visit our website at https://www.elsevier.com/books-and-journals

Publisher: Andre Gerhard Wolff

Editorial Project Manager: Mona Zahir

Production Project Manager: Sreejith Viswanathan

Cover Designer: Mark Rogers

Typeset by MPS Limited, Chennai, India

Dedication To my mom for her love and all the opportunities she gave me To the - photo 3

Dedication

To my mom for her love and all the opportunities she gave me.

To the memory of my father and my aunt Maria.

To my brother Luigi and his wife Pina, and my sister Maria and her husband Pietro for their continuous support that has made possible the fruition of my efforts.

To my nephews Vincenzo, Domenico, Vincenzo C., and Bruno and my nieces Caterina and Gemma for their nice encouragement.

To my closest friends.

List of contributors

Giada Alterini , Dipartimento delle Scienze Mediche, AOU Senese, Siena, Italy

Gabrio Bassotti , Gastroenterology and Hepatology Section, Department of Medicine, University of Perugia Medical School, Perugia, Italy

Massimo Bellini , Gastrointestinal Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

Teodora Surdea Blaga , 2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

Corrado Blandizzi , Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

Stefano Brillanti , Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze (DSMCN), Universita di Siena, Siena, Italy

Francesco Bronzini , Gastrointestinal Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

Rocchina Colucci , Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy

Dan L. Dumitrascu , 2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

Charlotte DMello , Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada

Francesca Fianchi , Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Gemelli IRCCS, Universit Cattolica del Sacro Cuore, Roma, Italy

Matteo Fornai , Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

Andrea Galli , Gastroenterology Unit, Department of Experimental and Clinical Biomedical Sciences, Florence, Italy

Simona Grad , 2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

Yong-Ku Kim , Department of Psychiatry, Korea University Ansan Hospital, Ansan, Kyunggido, Republic of Korea

Anna-Lena Laguna de la Vera , Department of Internal Medicine I, J.W. Goethe University Hospital, Frankfurt, Germany

Luca Maroni , Clinic of Gastroenterology and Hepatology, Universit Politecnica delle Marche, Ancona, Italy

Luca Miele , Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Gemelli IRCCS, Universit Cattolica del Sacro Cuore, Roma, Italy

Stefano Milani , Gastroenterology Unit, Department of Experimental and Clinical Biomedical Sciences, Florence, Italy

Waltraud Pfeilschifter , Department of Neurology, J.W. Goethe University Hospital, Frankfurt, Germany

Andrei V. Pop , 2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

Sandip Samanta , Department of Inflammation Biology, Faculty of Life Sciences and Medicine, School of Immunology and Microbial Sciences, Institute of Liver Studies, Kings College London, London, United Kingdom

Giulia Scalese , Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

Carola Severi , Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

Debbie L. Shawcross , Department of Inflammation Biology, Faculty of Life Sciences and Medicine, School of Immunology and Microbial Sciences, Institute of Liver Studies, Kings College London, London, United Kingdom

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