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Malcolm Kendrick - The Clot Thickens: The enduring mystery of heart disease

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Malcolm Kendricks masterly survey of the enduring mystery of heart disease reads like a detective story. With great verve he marshals the evidence for the two main contending theories, exonerates the presumed suspect and makes a formidable case for thrombogenesis (blood clotting) as the perpetrator. Witty, provocative and entertaining, The Clot Thickens packs a powerful scientific punch. Highly recommended.

Dr James Le Fanu
Doctor, journalist, author of The Rise and Fall of Modern Medicine.

Malcolm Kendricks new book brings to mind the quote from Thomas Huxley when he first learned of Darwins theory of evolution: how extremely stupid (of me) not to have thought of that. What Kendrick presents is nothing less than a unifying theory of heart disease, that explains why everything from sickle cell disease to diabetes to a stressful lifestyle increases cardiovascular risk (and he does it with a large dollop of humour). After decades stuck in the blind alley that is the LDL hypothesis, this book is a revelation. It should be read by anyone with even a slight interest in understanding heart disease and what they can do to protect themselves from it.
Dr Sebastian Rushworth
M.D. Sweden


This is a 150-year detective story with a cast of unrecognised heroes who may, finally, become known for their work on the true causes of heart disease. Exploring the truth about cholesterol - the apparently tried, and convicted, cause of millions of deaths from heart disease - with billions spent each year on lowering cholesterol with diet and drugs.
Is it possible that our villain was simply left holding the gun whilst the true culprits ran and hid? Have they escaped our clutches?
Dr Kendrick also introduces us to a range of other lesser known characters in this tale of selective reporting, data manipulation and intrigue. The true story of heart disease is out there, and the evidence has been brought together here - a scientific mystery for our time that is ready to unfold.

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The Clot
Thickens

The enduring mystery

of heart disease

Dr Malcolm Kendrick

Copyright

Published by Columbus Publishing Ltd 2021
www.columbuspublishing.co.uk

ISBN: 978-1-907797-774
Rev: 20211025

Copyright 2021 Dr Malcolm Kendrick

Dr Malcolm Kendrick has asserted his rights to be identified as the author of this work in accordance with the Copyright, Designs and Patents Act 1988.

All rights reserved. This book may not, in whole or part, be copied, photocopied, reproduced, or reduced in any form of electronic
medium or machine-readable form without prior consent,
in writing, from the Author.

Design by Raffaele Bolelli Gallevi

Brand and product names are trademarks or registered trademarks of their respective owners.

The content of this book is intended to inform, entertain and provoke your thinking. This is not intended as medical advice. It may, however, make you question current medical and nutritional advice.
That is your choice. Its your life and health in your hands.

Neither the author nor the publisher can be held responsible or liable for any loss or claim arising from the use, or misuse, of the content of this book.

Reviews Malcolm Kendricks masterly survey of the enduring mystery of heart - photo 1

Reviews

Malcolm Kendricks masterly survey of the enduring mystery of heart disease reads like a detective story. With great verve he marshals the evidence for the two main contending theories, exonerates the presumed suspect and makes a formidable case for thrombogenesis (blood clotting) as the perpetrator. Witty, provocative and entertaining, The Clot Thickens packs a powerful scientific punch. Highly recommended.

Dr James Le Fanu, Doctor, Journalist, Author of
The Rise and Fall of Modern Medicine

For everyone who believes that there is more to heart disease than avoiding fat or taking a statin this book will confirm your thinking. The Clot Thickens strips away the idea that high cholesterol is the key underlying cause of heart disease. Replacing it with evidence exposing the true culprits.

Entertaining, understandable, and fascinating, this unique and cutting-edge work (I call it a living text book) shows that for decades the causes of heart disease have simply been swept under the table. Whether you have heart disease, know someone with it, if you fear it, or you are just interested in it, this meticulously researched book will shake up every aspect of your thinking. It will also help you to understand exactly what you can do to reduce your risk.

Lucy Johnston, Health and Social Affairs Editor, Sunday Express

Science evolves by being challenged. Not by being followed. Malcolm Kendrick, proves once again, he is not a follower. The Enduring Mystery of heart disease - The Clot Thickens clearly questions the current cholesterol causes cardiovascular disease paradigm held by most doctors. Anyone stating that we, as a medical profession, have heart disease worked out, has stopped the scientific method in its tracks. They have stopped questioning and thinking. Thats a worry for patients everywhere.

Dr Gary Fettke, M.B.,B.S.(UNSW), F.R.A.C.S., F.A.Orth.A

What I really liked about this book (in addition to the title!) is Dr Kendricks logical, evidenced approach to the true causes of heart disease, paired with pragmatic information as to what each of us can do to actually live longer. The good news is so much of our fate is in our own hands, as I know so well from my own clinical work helping people with T2 Diabetes to cut the carbs. Here is an experienced clinician who just wants you to live longer. READ THE BOOK!!

Dr David Unwin, M.D UK

Whether you agree or disagree with the Authors conclusions, what shines through is his decades of dedicated, independent investigation into the possible causes of heart disease. His style of writing is humorous and at times irreverent but engaging throughout. And it is always good to debate our pool of knowledge so we can try to make sense of it ourselves.

Dr Rob Lawson., Chairman British Society of Lifestyle Medicine

To anyone aware of the contradictions and misconceptions involved in the official medical view of cholesterol, Dr Malcolm Kendrick is a hero. A fearless, independent voice challenging the official, and vastly profitable, theory that heart disease is the result of too much of it.

To support his case, Kendrick has been diving for decades into the arcane regions of cholesterol biology, returning with findings which demonstrate that the official theory is profoundly flawed. He reports them in detailed but clear, non-specialist prose, spiced with humour. For his pains he has been effectively medically excommunicated.

Undaunted he has been developing an alternative theory, set out in his new book The Clot Thickens. It describes the essential changes in your system that make heart disease more likely, complete with an arsenal of references. This is serious research.

Jerome Burne, Award winning medical journalist

Malcolm Kendrick is a rare beast. A natural skeptic, contrarian and a GP obsessed for his entire adult life with the causes of heart disease. This book is his Hegelian antithesis to the collective dogma of modern Cardiology. He presents a witty Poirot-like walk through the potential culprits responsible for the development of coronary artery disease. Has he spotted major clues that all the major researchers in the world have failed to? We may never know! However, his researched opinions should be given credit and future academic consideration.

Dr Scott W Murray, MBChB, BSc, MRCP, MD, Consultant Cardiologist Venturi Cardiology; Past President of the British Association of Cardiovascular Prevention and Rehabilitation (BACPR)

Malcolm Kendricks new book brings to mind the quote from Thomas Huxley when he first learned of Darwins theory of evolution: how extremely stupid (of me) not to have thought of that. What Kendrick presents is nothing less than a unifying theory of heart disease, that explains why everything from sickle cell disease to diabetes to a stressful lifestyle increases cardiovascular risk (and he does it with a large dollop of humour). After decades stuck in the blind alley that is the LDL hypothesis, this book is a revelation. It should be read by anyone with even a slight interest in understanding heart disease and what they can do to protect themselves from it.

Dr Sebastian Rushworth, M.D. Sweden

In The Clot Thickens, Malcolm Kendrick mounts a high caliber fusillade against the diet-heart-cholesterol hypothesis and, as the title suggests, presents the alternative: the role of the thrombogenic process. The medical establishment maintains extensive political Kevlar and it is not clear where things will go but the reader is provided a broad view of the medicine that bears on the interaction between coagulation and heart disease. Theres something to learn for everybody even those of us who have worked in related fields and who have followed previous warriors in this battle. When I first read Uffe Ravnskovs pioneering Cholesterol Myths, I thought it cant be this bad. I have to go back and read the original literature. I did and it was that bad. I never understood how the cholesterol idea could be sustained. In The Clot Thickens, Kendrick, a colleague and fellow admirer of Ravnskov, points out the limitations of the likely alternative at that time (bacterial or viral infection). He provides extensive evidence on the more compelling role of damage to the circulation and the role of thrombosis (clotting) and inhibition of fibrinolysis (clot breakdown). A far-ranging discussion with good straight-forward definitions of medical terms and includes some tantalizing stories to send you to the thorough set of references.

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