Mahfoozur Rahman - Nanomedicine for Bioactives: Healthcare Applications

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This book, Nanomedicine for Bioactives: Healthcare Applications, is the product of our sincere effort, to provide scientific evidence for the extraordinary power of natures wonder moleculesbioactives. Chapters by experts in different specific aspects of bioactive and its effective delivery by nanomedicines for better healthcare applications have been presented to our widespread readers and health professionals. Nanotechnology is an opening up for new perspectives in all scientific and technological fields. Among these applications, bioactive and nutraceuticals are the fast-growing fields in nano-research. A variety of nanoformulations such as polymeric nanoparticles , nanocapsules , nano emulsions, transferosomes and ethosomes, liposomes, lipospheres and lipid polymer hybrid nanoparticles have been reported for bioactive delivery and food materials. New herbal drugs and nutraceuticals-loaded nanomedicine are reported to have remarkable advantages over conventional formulations of plant actives and extracts which include enhancement of solubility, bioavailability, multiple drug delivery, expansion of stability, sustained delivery, improved tissue macrophages distribution, protection from toxicity, enhancement of pharmacological activity and protection from physical and chemical degradation.

A succinct account on key highlights of each of the chapter included in the book has been discussed in the below-mentioned text.

Chapteron the topic entitled Ganoderic acid for anticancer applications: Scope of nanomedicine in its effective delivery extensively covers the history ofG. lucidum, its traditional use and therapeutic application against cancer with molecular mechanism based on in vitro and in vivo experiments.

Chapterof Dr Akhbari on Vitamin E-based nanomedicines for anticancer drug delivery covers the role of vitamin which is a promising candidate for achieving patients dream: Chemotherapy at Home. Furthermore, vitamin E-based nanomedicines are suitable candidates for the preparation of novel anticancer treatments in the future.

Chapterof Dr Ahmad on Nanomedicine Approaches for the delivery of herbal anticancer drugs explores the use of nanomedicine to revolutionize the way to discover and administer the phytoconstituents in the patients.

In Chap., Dr B. Mukherjee describes the role of betulinic acid and its delivery by nanoformulation approach towards cancer therapy.

Dr S. Kumar in Chaps.summarizes the role of quercetin-loaded nanomedicine in cancer management and as nutritional applications.

Dr Farhan J. Ahmad in Chap.on Polyunsaturated fatty acids-loaded nanomedicine for solid tumour summarizes that the PUFA-loaded nanoformulations showing both anti-inflammatory and anti-neoplastic activities could make them more bioavailable. Whereas PUFAs helps in decreasing the adverse effects, lowering the toxicity, and targeting and affecting only the cancerous cell, without affecting the normal cells which are present in the human body.

Entesar Hanan in Chap.discusses the prospects of Nutraceuticals-loaded chitosan nanoparticles for healthcare applications and also highlights the superior characteristics of the said nanoparticles and its gained versatility in the effective delivery of nutraceuticals.

In Chap., Dr Deepika Singh discusses on Polyphenols-loaded nanomedicines against skin aging and broadly covers plant-derived polyphenols, its bioavailability, different types of nanocarriers for pharmaceutical and cosmetological purposes and product-oriented solutions used in skin aging.

Dr Kamalinder K. Singh in Chap.discusses on the emergence of lipid nanocarriers in the effective dermal delivery of lutein.

Dr Biswajit Mukherjee in Chap.describes the array of biological activities of apigenin and addresses the issues of delivering apigenin through nanocarriers to improve the efficacy of apigenin, more particularly in diabetes and various types of cancer.

In Chap., Dr Dinesh K. Patel discusses the importance ofAegle marmelosand their phytochemical aeglin in various therapeutic healthcare applications.

Dr Nupur Garg in Chap.summarizes the clinical applications and epigallocatechin-3-gallate which combined with the nanosystems hold a promising future for advancements in the therapeutic applications of natural products.

In Chap., Mohamad Taleuzzaman describes the chemical and biological applications of eugenol and eugenol nanoformulations. It has abundant potential applications and are sure to be incorporated in future into commercially available products and new uses/processes are lying in wait to be explored.

Dr Madhu Khatri in Chap.focuses on regulations for proper usage of nanomaterials and also highlights the currently existing regulations for safe delivery of drug molecules.

In Chap., Dr Madhu Gupta discusses the intake of fruits and vegetables has enhanced the level of components having antioxidative effects such as vitamin C, vitamin E, selenium, lycopene and several phytochemicals in the treatment of cancer as nutritional value.