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2019 by the American Diabetes Association, Inc. All Rights Reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including duplication, recording, or any information storage and retrieval system, without the prior written permission of the American Diabetes Association.
Printed in the United States of America
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The suggestions and information contained in this publication are generally consistent with the Standards of Medical Care in Diabetes and other policies of the American Diabetes Association, but they do not represent the policy or position of the Association or any of its boards or committees. Reasonable steps have been taken to ensure the accuracy of the information presented. However, the American Diabetes Association cannot ensure the safety or efficacy of any product or service described in this publication. Individuals are advised to consult a physician or other appropriate health care professional before undertaking any diet or exercise program or taking any medication referred to in this publication. Professionals must use and apply their own professional judgment, experience, and training and should not rely solely on the information contained in this publication before prescribing any diet, exercise, or medication. The American Diabetes Associationits officers, directors, employees, volunteers, and membersassumes no responsibility or liability for personal or other injury, loss, or damage that may result from the suggestions or information in this publication.
The paper in this publication meets the requirements of the ANSI Standard Z39.48-1992 (permanence of paper).
American Diabetes Association titles may be purchased for business or promotional use or for special sales. To purchase more than 50 copies of this book at a discount, or for custom editions of this book with your logo, contact the American Diabetes Association at the address below or at .
American Diabetes Association
2451 Crystal Drive, Suite 900
Arlington, VA 22202
DOI: 10.2337/9781580407007
Library of Congress Cataloging-in-Publication Data
Names: White, John R., Jr., 1958- editor. | American Diabetes Association, issuing body.
Title: 2019 guide to medications for the treatment of diabetes mellitus / John R. White Jr., editor.
Other titles: Guide to medications for the treatment of diabetes mellitus | Medications for the treatment of diabetes mellitus
Description: Arlington : American Diabetes Association, [2019] | Includes bibliographical references.
Identifiers: LCCN 2018056668 | ISBN 9781580407007 (softcover : alk. paper)
Subjects: | MESH: Diabetes Mellitusdrug therapy | Insulinspharmacology | Hypoglycemic Agentspharmacology
Classification: LCC RC661.I6 | NLM WK 815 | DDC 616.4/62061--dc23
LC record available at https://lccn.loc.gov/2018056668
This book is dedicated to the memory of R. Keith Campbell.
Keith was a close friend, a mentor, and an inspiration to me as well as to innumerable other healthcare providers, patients, students, and other people. This book was originally his brainchild. He co-edited each of the previous editions/permutations of this book.
Keith was diagnosed with type 1 diabetes when he was 8 years old. He lived with diabetes for more than 68 years, all the while remaining positive and helping myriad others with diabetes. He was always firmly at the forefront of knowledge in the diabetes arena. He published more than 600 manuscripts, 14 books, 55 book chapters, and made over 1,500 professional presentations. His multifaceted career at Washington State University as an academic spanned 45 years and included many roles and titles. He received numerous awards including the American College of Clinical Pharmacys Paul F. Parker Medal, the National Community Pharmacists Associations Outstanding Pharmacy Administration Professor in the U.S., the American Diabetes Associations Outstanding Health Care Educator in the Field of Diabetes, and the American Association of Diabetes Educators (AADEs) Distinguished Service Award. He served on the board of directors of the American Diabetes Association, Washington State Pharmacy Association, and AADE. He was beloved by his friends, family, and students, and was known for his outgoing personality. He was a remarkable, one-of-a-kind individual who is greatly missed. He will always be remembered for his indefatigable ability to manage a difficult, complicated, chronic disease with grace, for his larger-than-life personality, and for his ever-present cat-that-caught-the-mouse smile.
John R. White, Jr.
Contents
Joshua J. Neumiller, PharmD, CDE, FASCP
Joshua J. Neumiller, PharmD, CDE, FASCP, and Kimberly C. McKeirnan, PharmD, BCACP
John R. White, Jr., PA-C, PharmD
Peggy Soule Odegard, BSPharm, PharmD, CDE; Jennifer Danielson, PharmD, CDE; and Kam L. Capoccia, PharmD, BCPS, CDE
Kam L. Capoccia, PharmD, BCPS, CDE; Jennifer Danielson, PharmD, CDE; and Peggy Soule Odegard, BSPharm, PharmD, CDE
Lisa Kroon, PharmD, and Crystal Zhou, PharmD
Lisa Kroon, PharmD, and Crystal Zhou, PharmD
John R. White, Jr., PA-C, PharmD
Kimberly C. McKeirnan, PharmD, BCACP, and Nicole M. Perea, PharmD
Kimberly C. McKeirnan, PharmD, BCACP, and Joshua J. Neumiller, PharmD, CDE, FASCP
Jennifer M. Trujillo, PharmD, BCPS, FCCP, CDE, BC-ADM
Jennifer M. Trujillo, PharmD, BCPS, FCCP, CDE, BC-ADM
Christina R. Buchman, PharmD, BCACP
Christina R. Buchman, PharmD, BCACP
Cheyenne Newsome, PharmD, PhC, BCACP
Cheyenne Newsome, PharmD, PhC, BCACP
Megan Willson, PharmD, BCPS, and Kimberly C. McKeirnan, PharmD, BCACP
Anne P. Kim, PharmD, MPH, MIT
Damianne Brand-Eubanks, PharmD, and Anne P. Kim, PharmD, MPH, MIT
Emmeline Tran, PharmD
Emmeline Tran, PharmD
Megan Willson, PharmD, BCPS
Megan Giruzzi, PharmD, BCPS
Nicholas R. Giruzzi, PharmD, BCPS
Kimberly C. McKeirnan, PharmD, BCACP, and Nicole M. Perea, PharmD
Contributors
EDITOR
John R. White, Jr., PA-C, PharmD
Professor and Department Chair
Department of Pharmacotherapy
College of Pharmacy and Pharmaceutical Sciences
Washington State University
Spokane, WA
CONTRIBUTORS
Damianne Brand-Eubanks, PharmD
Clinical Assistant Professor, Pharmacotherapy
College of Pharmacy and Pharmaceutical Sciences
Washington State University
Yakima, WA
Christina R. Buchman, PharmD, BCACP
Clinical Assistant Professor, Pharmacotherapy
College of Pharmacy and Pharmaceutical Sciences
Washington State University