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Paul J. Mitchell - Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences

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A practical guide to the use of basic principles of experimental design and statistical analysis in pharmacology Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences provides clear instructions on applying statistical analysis techniques to pharmacological data. Written by an experimental pharmacologist with decades of experience teaching statistics and designing preclinical experiments, this reader-friendly volume explains the variety of statistical tests that researchers require to analyze data and draw correct conclusions. Detailed, yet accessible, chapters explain how to determine the appropriate statistical tool for a particular type of data, run the statistical test, and analyze and interpret the results. By first introducing basic principles of experimental design and statistical analysis, the author then guides readers through descriptive and inferential statistics, analysis of variance, correlation and regression analysis, general linear modelling, and more. Lastly, throughout the textbook are numerous examples from molecular, cellular, in vitro, and in vivo pharmacology which highlight the importance of rigorous statistical analysis in real-world pharmacological and biomedical research. This textbook also: Describes the rigorous statistical approach needed for publication in scientific journals Covers a wide range of statistical concepts and methods, such as standard normal distribution, data confidence intervals, and post hoc and a priori analysis Discusses practical aspects of data collection, identification, and presentation Features images of the output from common statistical packages, including GraphPad Prism, Invivo Stat, MiniTab and SPSS Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences is an invaluable reference and guide for undergraduate and graduate students, post-doctoral researchers, and lecturers in pharmacology, graduate students and post-doctoral researchers in pharmacology and allied subjects in the life sciences.

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Table of Contents List of Tables Chapter 2 Chapter 3 Chapter 4 Chapter - photo 1
Table of Contents
List of Tables
  1. Chapter 2
  2. Chapter 3
  3. Chapter 4
  4. Chapter 5
  5. Chapter 6
  6. Chapter 7
  7. Chapter 8
  8. Chapter 9
  9. Chapter 10
  10. Chapter 11
  11. Chapter 12
  12. Chapter 13
  13. Chapter 14
  14. Chapter 15
  15. Chapter 16
  16. Chapter 17
  17. Chapter 18
  18. Chapter 19
  19. Chapter 20
  20. Chapter 21
  21. Chapter 23
List of Illustrations
  1. Chapter 1
  2. Chapter 3
  3. Chapter 4
  4. Chapter 5
  5. Chapter 6
  6. Chapter 7
  7. Chapter 8
  8. Chapter 9
  9. Chapter 10
  10. Chapter 15
  11. Chapter 16
  12. Chapter 19
  13. Chapter 20
Guide
Pages
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences

Paul J. Mitchell

Department of Pharmacy and Pharmacology University of Bath Bath, UK

Department of Pharmacology and Therapeutics National University of Ireland (NUI) Galway, Ireland

This edition first published 2022 2022 John Wiley and Sons Ltd All rights - photo 2

This edition first published 2022
2022 John Wiley and Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions .

The right of Paul J. Mitchell to be identified as the author of this work has been asserted in accordance with law.

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The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services.

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