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Joseph DiPiro - Pharmacotherapy: A Pathophysiologic Approach, Eleventh Edition

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Joseph DiPiro Pharmacotherapy: A Pathophysiologic Approach, Eleventh Edition

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25+ additional chapters available online!

The classic guide to driving optimal patient outcomes using evidence-based medication therapiesupdated with the latest advances and guidelines

A Doodys Core Title for 2020! ALL E-CHAPTERS (ONLINE ONLY CHAPTERS) NOW AVAILABLE FREE go to https://accesspharmacy.mhmedical.com/book.aspx?bookID=2577

Presented in full color, Pharmacotherapy: A Pathophysiologic Approach, 11th Edition helps you deliver the highest-quality patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. It takes you beyond drug indications and dosages, showing how to properly select, administer, and monitor drugseverything you need to provide safe, effective drug therapy across all therapeutic categories. With all-new monitoring tables and authoritative content from 300 expert contributors, this new edition has been fully updated to reflect the latest evidence-based information and recommendations. Youll find Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy.

Why Pharmacotherapy: A Pathophysiologic Approach is perfect for students, pharmacists, and other healthcare providers:

All chapters provide the most current, reliable, and relevant information available.
Key concepts kick off every chapter.
Clinical Presentation Tables summarize disease signs and symptoms.
The majority of sections include personalized pharmacotherapy content.
Clinical Controversies Boxes clarify the most complex drug therapy issues youll face.
Diagnostic flow diagrams, treatment algorithms, dosing recommendations, and monitoring approaches have been updated in full color to distinguish treatment pathways.
Most disease-oriented chapters are enhanced by updated evidence-based treatment guidelines, which often include ratings of the level of evidence to support key therapeutic approaches.
Instructors who adopt this text are eligible for a PowerPoint presentation of all images and answers to Self-Assessment Questions!

The most trusted guide of its kind for decades, Pharmacotherapy: A Pathophysiologic Approach is the go-to text for students and practitioners seeking clear, objective coverage of core pathophysiologic and therapeutic elements.

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PAST EDITORS OF PHARMACOTHERAPY

Peggy E. Hayes, PharmD

Editions 1 and 2

Gary R. Matzke, PharmD, FCP, FCCP, FASN, FNAP

Editions 210

Robert L. Talbert, PharmD, FCCP, BCPS, FAHA

Editions 110

Barbara G. Wells, PharmD, FCCP, FASHP

Editions 310

Copyright 2020 by McGraw Hill All rights reserved Except as permitted under - photo 1

Copyright 2020 by McGraw Hill. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher.

ISBN: 978-1-26-011682-3
MHID: 1-26-011682-4

The material in this eBook also appears in the print version of this title: ISBN: 978-1-26-011681-6, MHID: 1-26-011681-6.

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Notice

Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.

TERMS OF USE

This is a copyrighted work and McGraw-Hill Education and its licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Educations prior consent. You may use the work for your own noncommercial and personal use; any other use of the work is strictly prohibited. Your right to use the work may be terminated if you fail to comply with these terms.

THE WORK IS PROVIDED AS IS. McGRAW-HILL EDUCATION AND ITS LICENSORS MAKE NO GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill Education and its licensors do not warrant or guarantee that the functions contained in the work will meet your requirements or that its operation will be uninterrupted or error free. Neither McGraw-Hill Education nor its licensors shall be liable to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for any damages resulting therefrom. McGraw-Hill Education has no responsibility for the content of any information accessed through the work. Under no circumstances shall McGraw-Hill Education and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise.

Dedication

To our patients and students, who have challenged and inspired us and given meaning to all our endeavors.

To practitioners who continue to improve patient health outcomes and thereby serve as role models for their colleagues and students while clinging tenaciously to the highest standards of practice.

To our mentors, whose vision provided educational and training programs that encouraged our professional growth and challenged us to be innovators in our patient care, research, and education.

To our faculty colleagues for their efforts and support for our mission to provide a comprehensive and challenging educational foundation for the pharmacists of the future.

And finally to our families for the time that they have sacrificed so that this 11th edition would become a reality.

The Editors


In MemoriamBrian S. Decker, MD, PharmD, MS

Brian S. Decker (1963-2018), a coauthor of the Hemodialysis and Peritoneal Dialysis chapter in Pharmacotherapy since its eighth edition in 2012, received his BS in Wildlife Sciences and Pharmacy and PharmD degrees from Purdue University. He received his MD degree from Indiana University School of Medicine in 2003, and he completed a residency in Internal Medicine and Fellowships in Nephrology and Clinical Pharmacology at IU.

In 2007, Brian joined the faculty in the Indiana University School of Medicine in the Divisions of Nephrology and Clinical Pharmacology, and he simultaneously served as an Affiliate Faculty member in the Purdue University College of Pharmacy. During his time as a faculty member, he earned a MS in clinical research. Brian was an avid teacher of nephrology, pharmacology, and pharmacogenomics to trainees from both IU and Purdue.

Brian directed the Nephrology Fellowship Training Program, fostered Nephrology student interest groups, and was an active member of the IU Academy of Teaching Scholars. He was also very active locally and nationally in Nephrology and Pharmacology societies and in the local community.

Brians knowledge of pharmacy and medicine was evident through his ability to further our understanding of nephrology. His unique perspective was apparent in his contribution to the Hemodialysis and Peritoneal Dialysis chapter where he provided key treatment details in a manner that was understandable and clinically relevant. As his coauthors, we will miss his knowledge, clinical experience, and perspective.

Kevin M. Sowinski, PharmD, FCCP
Mariann D. Churchwell, PharmD, FCCP


Contents



Section Editor: Stuart T. Haines, L. Michael Posey, and Thomas D. Nolin

Stuart T. Haines, Mary Ann Kliethermes, and Todd Sorensen

Oralia V. Bazaldua, DeWayne A. Davidson, Ashley Zurek, and Sunil Kripalani

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