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Piero Picci - Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions: Clinical, Radiological and Histological Correlations - The Rizzoli Case Archive

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Piero Picci Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions: Clinical, Radiological and Histological Correlations - The Rizzoli Case Archive

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This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take into account nontumoral conditions. The recent identification of further significant biological and genetic features, and the impact of these discoveries on the classification of round cell tumors, vascular lesions, and spindle/pleomorphic entities in bone, is also extensively discussed. The Rizzoli case archive dates back to September 1900 and contains the original material relating to more than 29,000 bone lesions and 11,000 soft tissue lesions. It is a fabulously rich resource, and this book will be invaluable for pathologists, radiologists, and clinicians at all levels of experience.

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Editors Piero Picci Marco Manfrini Davide Maria Donati Marco Gambarotti - photo 1
Editors
Piero Picci , Marco Manfrini , Davide Maria Donati , Marco Gambarotti , Alberto Righi , Daniel Vanel and Angelo Paolo Dei Tos
Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions
Clinical, Radiological and Histological Correlations - The Rizzoli Case Archive
2nd ed. 2020
Editors Piero Picci ISG Italian Sarcoma Group Bologna Italy Marco - photo 2
Editors
Piero Picci
I.S.G. Italian Sarcoma Group, Bologna, Italy
Marco Manfrini
IIIrd Clinic of Orthopaedic Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
Davide Maria Donati
Istituto Ortopedico Rizzoli, Bologna, Italy
Marco Gambarotti
Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Alberto Righi
Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Daniel Vanel
Istituto Rizzoli, Bologna, Italy
Angelo Paolo Dei Tos
Department of Medicine, University of Padua School of Medicine, Padua, Italy
ISBN 978-3-030-29675-9 e-ISBN 978-3-030-29676-6
https://doi.org/10.1007/978-3-030-29676-6
corrected publication 2020
Springer Nature Switzerland AG 2020
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

This book is dedicated to

Prof. Mario Campanacci,

Prof. Mario Mercuri,

Dr. Gaetano Bacci, and

Dr. Marco Alberghini

who strongly supported the dissemination

of knowledge of musculoskeletal tumors.

Preface

This is a second book based on the data of the Rizzoli case archive, after the one published in 2014 with the titleAtlas of Musculoskeletal Tumors and Tumorlike Lesions: The Rizzoli Case Archive.

In this new one, not only the epidemiological data are updated with the addition of about 7000 new lesions diagnosed in 5 years between 2013 and 2017, but also some chapters were added and/or modified based on the more recent discoveries in terms of clinical, histological, and molecular investigations.

In particular, small blue round cell tumors are deeply analyzed and presented, as the whole spectrum of vascular lesions, with the introduction of new entities, as for the presentation of a new classification for those sarcomas of bone in the past simply diagnosed as malignant fibrous histiocytoma or fibrosarcoma. More space is also dedicated to soft tissue lesions and also to those more rare entities not discussed in the previous book.

What presented reflects the experience of the Rizzoli Orthopedic Institute in over 100 years of treatment of musculoskeletal tumors and tumorlike lesions. The first treated case dated September 28, 1900, and the archive contains the original material (clinical charts, imaging, paraffin blocks, and histological slides) of more than 47,000 cases (about 32,000 bone lesions and 15,000 soft tissue lesions).

Each single entity is presented multidisciplinarily, with the pertinent clinical, radiological, and histological correlations. The treatment is briefly reported for each entity. Other separate chapters analyze the more recent biomolecular findings useful for diagnosis, prognosis, and treatment.

The text reflects the improvements in knowledge of musculoskeletal tumors as presented during the yearly international course held at the Rizzoli Institute.

This course, promoted by Prof. Mario Campanacci since 1970, has seen the participation as guest professors of the major international experts in musculoskeletal lesions:
  • D. Dahlin (Rochester) 1974, 1984

  • W.F. Enneking (Gainsville) 1984, 19891990, 19921994, 1998, 2004

  • N. Jaffe (Houston) 1984

  • D. Springfield (Gainsville, New York, Boston) 1995, 1997, 2000, 20022007

  • J.M. Mirra (Los Angeles) 1996, 2008

  • H. Mankin (Boston) 1999

  • A.L. Schiller (Boston) 2002

  • D. Vanel (Villejuif-Bologna) 2003, 2005, 20072018

  • P.C.W. Hogendoorn (Leiden) 20062008

  • N. Athanasou (Oxford) 2008

  • M.C. Gebhardt (Boston) 20082017

  • F.H. Sim (Rochester) 20102011

  • M.I. OConnor (Jacksonville) 20112013

  • J.M. Coindre (Bordeaux) 2011

  • M.J. Klein (New York) 20122017

  • N. Fabbri (New York) 20132017

  • J.H. Healey (New York) 20132014

  • A.P. Dei Tos (Treviso) 20132019

  • S. Cammelli (Bologna University) 20162019

  • R. Grimer (Birmingham) 20172019

  • R. Windhager (Wien) 20182019

Rizzoli collaborators to the Annual Course of the last years:
Patrizia Bacchini

Pathology

Alberto Bazzocchi

Radiology

Maria Serena Benassi

Biology

Stefania Benini

Biology

Franco Bertoni

Pathology

Roberto Biagini

Orthopaedics

Giuseppe Bianchi

Orthopaedics

Stefano Boriani

Orthopaedics

Laura Campanacci

Orthopaedics

Roberto Casadei

Orthopaedics

Marco Colangeli

Orthopaedics

Massimiliano De Paolis

Orthopaedics

Davide Maria Donati

Orthopaedics

Costantino Errani

Orthopaedics

Nicola Fabbri

Orthopaedics

Stefano Ferrari

Oncology

Andrea Ferraro

Orthopaedics

Tommaso Frisoni

Orthopaedics

Marco Gambarotti

Pathology

Alessandro Gasbarrini

Orthopaedics

Claudia Hattinger

Biology

Marco Manfrini

Orthopaedics

Emanuela Palmerini

Oncology

Piero Picci

Oncology

Alberto Righi

Pathology

Eugenio Rimondi

Radiology

Pietro Ruggieri

Orthopaedics

Katia Scotlandi

Biology

Massimo Serra

Biology

Eric Staals

Orthopaedics

Daniel Vanel

Radiology

Licciana Zanella

Biology

Piero Picci
Marco Manfrini
Davide Maria Donati
Marco Gambarotti
Alberto Righi
Daniel Vanel
Angelo Paolo Dei Tos
Bologna, Italy Bologna, Italy Bologna, Italy Bologna, Italy Bologna, Italy Bologna, Italy Padua, Italy
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