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Akete Lex Adjei - Inhalation delivery of therapeutic peptides and proteins

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Inhalation delivery of therapeutic peptides and proteins: summary, description and annotation

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This exhaustive reference-the first book of its kind to describe in detail the functionality of the human respiratory tract and its impact on both local and systemic delivery of biotherapeutic and macromolecular drug systems-offers comprehensive analyses of peptide and protein drug delivery through the lung. Summarizes over 130 patents granted worldwide on alternative systems for pulmonary delivery of therapeutic drugs-especially peptides and proteins! Examining macromolecular drug delivery as an efficient, patient-friendly, and cost-effective method of treatment, Inhalation Delivery of Therapeutic Peptides and Proteins discusses airway physiology and biomechanics the pharmaceutical concerns associated with the respiratory tract as a viable port of drug entry to the body key peptide drugs under development and in use to treat local lung disease, including cyclosporines, interferons, antitrypsins, protease inhibitors, and deoxyribonucleases the systemic delivery of peptide and protein drugs using fine-particle technology gene therapy employing gene delivery through the airways new developments in pulmonary delivery technologies emphasizing inhaled peptide and protein drugs guidelines for the successful introduction of peptide inhalation aerosol products into the marketplace and much more!

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title Inhalation Delivery of Therapeutic Peptides and Proteins Lung - photo 1

title:Inhalation Delivery of Therapeutic Peptides and Proteins Lung Biology in Health and Disease ; V. 107
author:Adjei, Akete Lex
publisher:Informa Healthcare
isbn10 | asin:0824797809
print isbn13:9780824797805
ebook isbn13:9780585158679
language:English
subjectProtein drugs--Dosage forms, Peptide drugs--Dosage forms, Aerosol therapy, Administration, Inhalation, Drug Delivery Systems, Aerosols, Peptides--therapeutic use, Proteins--therapeutic use.
publication date:1997
lcc:RS431.P75I54 1997eb
ddc:615/.6
subject:Protein drugs--Dosage forms, Peptide drugs--Dosage forms, Aerosol therapy, Administration, Inhalation, Drug Delivery Systems, Aerosols, Peptides--therapeutic use, Proteins--therapeutic use.
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Inhalation Delivery of Therapeutic Peptides and Proteins
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LUNG BIOLOGY IN HEALTH AND DISEASE
Executive Editor
Claude Lenfant
Director, National Heart, Lung and Blood Institute
National Institutes of Health
Bethesda, Maryland
1. Immunologic and Infectious Reactions in the Lung, edited by Charles H. Kirkpatrick and Herbert Y. Reynolds
2. The Biochemical Basis of Pulmonary Function, edited by Ronald G. Crystal
3. Bioengineering Aspects of the Lung, edited by John B. West
4. Metabolic Functions of the Lung, edited by Y. S. Bakhle and John R. Vane
5. Respiratory Defense Mechanisms (in two parts), edited by Joseph D. Brain, Donald F. Proctor, and Lynne M. Reid
6. Development of the Lung, edited by W. Alan Hodson
7. Lung Water and Solute Exchange, edited by Norman C. Staub
8. Extrapulmonary Manifestations of Respiratory Disease, edited by Eugene Debs Robin
9. Chronic Obstructive Pulmonary Disease, edited by Thomas L. Petty
10. Pathogenesis and Therapy of Lung Cancer, edited by Curtis C. Harris
11. Genetic Determinants of Pulmonary Disease, edited by Stephen D. Litwin
12. The Lung in the Transition Between Health and Disease, edited by Peter T. Macklem and Solbert Permutt
13. Evolution of Respiratory Processes: A Comparative Approach, edited by Stephen C. Wood and Claude Lenfant
14. Pulmonary Vascular Diseases, edited by Kenneth M. Moser
15. Physiology and Pharmacology of the Airways, edited by Jay A. Nadel
16. Diagnostic Techniques in Pulmonary Disease (in two parts), edited by Marvin A. Sackner
17. Regulation of Breathing (in two parts), edited by Thomas F. Hornbein
18. Occupational Lung Diseases: Research Approaches and Methods, edited by Hans Weil and Margaret Turner-Warwick
19. Immunopharmacology of the Lung, edited by Harold H. Newball
20. Sarcoidosis and Other Granulomatous Diseases of the Lung, edited by Barry L. Fanburg
21. Sleep and Breathing, edited by Nicholas A. Saunders and Colin E. Sullivan
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22. Pneumocystis carinii Pneumonia: Pathogenesis, Diagnosis, and Treatment, edited by Lowell S. Young
23. Pulmonary Nuclear Medicine: Techniques in Diagnosis of Lung Disease, edited by Harold L. Atkins
24. Acute Respiratory Failure, edited by Warren M. Zapol and Konrad J. Falke
25. Gas Mixing and Distribution in the Lung, edited by Ludwig A. Engel and Manuel Paiva
26. High-Frequency Ventilation in Intensive Care and During Surgery, edited by Graziano Carlon and William S. Howland
27. Pulmonary Development: Transition from Intrauterine to Extrauterine Life, edited by George H. Nelson
28. Chronic Obstructive Pulmonary Disease: Second Edition, Revised and Expanded, edited by Thomas L. Petty
29. The Thorax (in two parts), edited by Charis Roussos and Peter T. Macklem
30. The Pleura in Health and Disease, edited by Jacques Chrtien, Jean Bignon, and Albert Hirsch
31. Drug Therapy for Asthma: Research and Clinical Practice, edited by John W. Jenne and Shirley Murphy
32. Pulmonary Endothelium in Health and Disease, edited by Una S. Ryan
33. The Airways: Neural Control in Health and Disease, edited by Michael A. Kaliner and Peter J. Barnes
34. Pathophysiology and Treatment of Inhalation Injuries, edited by Jacob Loke
35. Respiratory Function of the Upper Airway, edited by Oommen P. Mathew and Giuseppe Sant'Ambrogio
36. Chronic Obstructive Pulmonary Disease: A Behavioral Perspective, edited by A. John McSweeny and lgor Grant
37. Biology of Lung Cancer: Diagnosis and Treatment, edited by Steven T. Rosen, James L. Mulshine, Frank Cuttitta, and Paul G. Abrams
38. Pulmonary Vascular Physiology and Pathophysiology, edited by E. Kenneth Weir and John T. Reeves
39. Comparative Pulmonary Physiology: Current Concepts, edited by Stephen C. Wood
40. Respiratory Physiology: An Analytical Approach, edited by H. K. Chang and Manuel Paiva
41. Lung Cell Biology, edited by Donald Massaro
42. Heart-Lung Interactions in Health and Disease, edited by Steven M. Scharf and Sharon S. Cassidy
43. Clinical Epidemiology of Chronic Obstructive Pulmonary Disease, edited by Michael J. Hensley and Nicholas A. Saunders
44. Surgical Pathology of Lung Neoplasms, edited by Alberto M. Marchevsky
45. The Lung in Rheumatic Diseases, edited by Grant W. Cannon and Guy A. Zimmerman
46. Diagnostic Imaging of the Lung, edited by Charles E. Putman
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47. Models of Lung Disease: Microscopy and Structural Methods, edited by Joan Gil
48. Electron Microscopy of the Lung, edited by Dean E. Schraufnagel
49. Asthma: Its Pathology and Treatment, edited by Michael A. Kaliner, Peter J. Barnes, and Carl G. A. Persson
50. Acute Respiratory Failure: Second Edition, edited by Warren M. Zapol and Francois Lemaire
51. Lung Disease in the Tropics, edited by Om P. Sharma
52. Exercise: Pulmonary Physiology and Pathophysiology, edited by Brian J. Whipp and Karlman Wasserman
53. Developmental Neurobiology of Breathing, edited by Gabriel G. Haddad and Jay P. Farber
54. Mediators of Pulmonary Inflammation, edited by Michael A. Bray and Wayne H. Anderson
55. The Airway Epithelium, edited by Stephen G. Farmer and Douglas Hay
56. Physiological Adaptations in Vertebrates: Respiration, Circulation, and Metabolism,
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