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Jollie William P. - Biology of the Uterus

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Jollie William P. Biology of the Uterus

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1 History -- 1. Greece -- 2. Alexandria -- 3. Rome -- 4. The Dark Ages -- 5. Renaissance -- 6. Seventeenth to Early Twentieth Centuries -- 7. Contemporary -- 8. References -- 2 Comparative Anatomy -- 1. Types of Uteri -- 2. Distribution and Probable Evolution of Uterine Types -- 3. Correlations of Uterine Types with Other Biological Features -- 4. Miscellaneous Aspects of the Comparative Morphology of the Uterus -- 5. Summary and Conclusions -- 6. References -- 7. Bibliography -- 3 Prenatal Human Development -- 1. Urinary Preliminaries -- 2. The Paramesonephric Ducts -- 3. The Vaginal Controversy -- 4. The Fetal Uterus -- 5. The Second Half of Prenatal Life -- 6. References -- 4 Vascular Anatomy -- 1. Basic Aspects of Architecture and Physiology of Uterine Arteries -- 2. Interaction of Trophoblast and Decidua -- 5 Vascular Physiology of the Nonpregnant Uterus -- 1. Fundamental Characteristics of the Uterine Vasculature -- 2. Uterine Blood Flow during the Ovarian Cycle -- 3. Mediators of Estrogen-Induced Vasodilatation -- 4. Responses of the Nonplacental Uterine Vasculature during Pregnancy -- 5. Conclusion -- 6. References -- 6 Cellular Biochemistry of the Endometrium -- 1. Methodological Comments -- 2. Intracellular Constituents -- 4. Extracellular Matrix -- 5. Secretory Components -- 6. Concluding Remarks -- 7. References -- 7 Cell Biology of the Endometrium -- 1. Mechanism of Hormone Action -- 2. Steroid Receptors -- 3. References -- 8 The Endometrium of Delayed and Early Implantation -- 1. Marsupials -- 2. Roe Deer -- 3. Armadillos -- 4. Insectivores and Chiroptera -- 5. Carnivores -- 6. Rodents -- 7. Nonhuman Primates -- 8. Discussion -- 9. References -- 9 The Implantation Reaction -- 1. Adhesion -- 2. Vascular Permeability -- 3. The Decidual Cell Reaction -- 4. Epithelial Cell Loss -- 5. References -- 10 Regeneration in the Primate Uterus: The Role of Stem Cells -- 1. Endometriectomy and the Location of the Endometrial Stem Cells -- 2. Compartmentalization of the Primate Endometrium -- 3. Zonation of the Primate Endometrium -- 4. Cyclic Changes in Endometrial Zonal Uptake of [3H]Thymidine -- 5. Hypothesis: Cyclic Endometrial Renewal in Menstruating Primates -- 6. References -- 11 The Human Endometrium: Cyclic and Gestational Changes -- 1. Histology -- 2. Ultrastructure -- 3. Clinical Correlations -- 4. Structural Vascular Changes in Normal and Hypertensive Pregnancies -- 12 Endometrial Hyperplasia and Neoplasia -- 1. Laboratory Evidence -- 2 Clinical Evidence -- 3. Coexistent Association -- 4. Clinical Implications of the Two-Disease Concept -- 5. References -- 13 Biochemistry of the Myometrium and Cervix -- 1. The Structure of the Myometrium -- 2. Calcium and Contractile Regulation -- 3. Regulation of Transmembrane Ca2+ Fluxes -- 4. Contractile Proteins of the Myometrium -- 5. Regulation of Myometrial Contractility -- 6. Mechanisms of Smooth Muscle Regulation Other Than MLCK -- 7. Integrated Model for Regulation of Smooth Muscle Contractility -- 8. Preterm Birth and Tocolytic Therapy -- 9. Cervix -- 10. References -- 14 Electrophysiological Properties of Uterine Smooth Muscle -- 1. Review of Methodology -- 2. Ionic Distribution as the Basis of Electrophysiological Phenomena -- 3. Electrical Activity of the Myometrium and Other Mammalian Smooth Muscles -- 4. Summary and Concluding Remarks -- 5. References -- 15 Ultrastructure of the Myometrium -- 1. Cellular Organization of the Myometrium -- 2. Ultrastructure of Myometrial Smooth Muscle Cells -- 3. Gap Junctions and Cell-to-Cell Communication in the Myometrium -- 4. Contractile Mechanism of Myometrial Smooth Muscle Cells -- 5. Conclusion -- 6. References -- 16 Uterine Control of Ovarian Function -- 1. Ovarian Function -- 2. Uterine Function -- 3. Uterine-Ovarian and Conceptus Interaction in Regulation of Ovarian Function -- 4. Luteolytic Actions of the Uterus: Effects of Hysterectomy on Ovarian Function -- 5. Uterine-Ovarian Hormones and Ovarian Function -- 6. Mechanisms of Uterine-Ovarian Interactions in Regulating Ovarian Function -- 7. References -- 17 Endocrine Control of Parturition -- 1. Problems in Understanding Basic Mechanisms of Parturition -- 2. Preparation of the Uterus for Labor: Estrogen -- 3. Uterine Quiescence -- 4. Activators of Uterine Activity -- 5. Cervical Distensibility -- 6. A General Model for Parturition -- 7. Unification of Mechanisms Proposed for Spontaneous Labor Induction -- 8. References.;Almost a quarter of a century has elapsed since Cellular Biology of the Uterus, the predecessor of the present volume, was planned. During that period, especially in the decade since the publication of the last edition of Biology of the Uterus, new information in the field has been so voluminous as to require major revisions of most of the chapters, the addition of several new chapters, and the collaboration of a second editor to facilitate the selection of appropriate experts as authors. As in prior editions, a balance has been struck between classical biology and modem biochemistry and biophysics. The inclusion of basic histological and embryo logical information provides a necessary, though often lacking, background for the protein chemist and molecular biologist and a bridge between the cell biologist and clinician. Thus, major practical problems in human reproduction, such as the genesis of endometrial carcinoma and the cause of the initiation of labor, may be approached on a firm scientific footing. The current edition deals primarily with the biology of the uterus itself (comparative and human) rather than placentation or pregnancy and thus is a synthesis of data derived from many techniques, both conventional and modem. As it is clearly beyond the competence of anyone scientist to prepare such a text on the basis of personal knowledge and experience, the aid of 22 distinguished scientists was enlisted.

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Biology of the Uterus Second Edition Book Editors Ralph M Wynn MD 12 - photo 1
Biology of the Uterus Second Edition
Book Editors
Ralph M. Wynn M.D. 1,2 Professor
William P. Jollie Ph.D. 3 Professor and Chairman
(1)
Department of Obstetrics & Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA
(2)
Department of Anatomy & Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA
(3)
Department of Anatomy, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
ISBN 978-1-4684-5591-5 ISBN 978-1-4684-5589-2 (eBook)
DOI 10.1007/978-1-4684-5589-2
Plenum Publishing Corporation 1989
Softcover reprint of the hardcover 1st edition 1989
All rights reserved.
No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
www.springer.com
Contributors
L. L. Anderson
Department of Animal Science
Iowa State University
Ames, Iowa 50011
John D. Aplin
Departments of Obstetrics and
Gynaecology, Biochemistry, and Molecular Biology
University of Manchester Manchester M13 OJK, England
Christine Bergeron
Departments of Pathology and Obstetrics and Gynecology
McGill University and The Sir Mortimer B. Davis Jewish
General HospitalMontreal, Quebec H3T 1E2,
Canada
W. C. Cole
Division of Cardiovascular Sciences St. Boniface Research Institute
Department of Physiology University of Manitoba
Winnipeg, Manitoba R2H 2AG,
Canada
Allen C. Enders
Department of Human Anatomy
University of California School of Medicine
Davis, California 95616
Alex Ferenczy
Departments of Pathology and Obstetrics and Gynecology
McGill University and The Sir Mortimer B. Davis Jewish
General Hospital Montreal, Quebec H3T 1E2,
Canada
R. E. Garfield
Departments of Neurosciences and Obstetrics and Gynecology
McMaster University, Health Sciences
Hamilton, Ontario L8N 3Z5,
Canada
Randall L. Given
Department of Anatomy and Neurosciences
University of Texas Medical Branch
Galveston, Texas 77550
Frank C. Greiss, Jr.
Department of Obstetrics and Gynecology
Bowman Gray School of Medicine of Wake Forest University
Winston-Salem, North Carolina 27103
Gabor Huszar
Department of Obstetrics and Gynecology
Yale University School of Medicine New Haven, Connecticut 06510
C. Y. Kao
Department of Pharmacology State University of New York
Downstate Medical Center Brooklyn, New York 11203
Wendell W. Leavitt
Departments of Biochemistry and Obstetrics and Gynecology
Texas Tech University Health Sciences Center
Lubbock, Texas 79430
Harland W. Mossman
Department of Anatomy University of Wisconsin-Madison
Madison, Wisconsin 53706
A. I Musah
Department of Animal Science Iowa State University
Ames, Iowa 50011
Ronan ORahilly
Carnegie Laboratories of EmbryologyCalifornia Primate Research Center Davis, California 95616
Helen A. Padykula
Department of Cell Biology University of Massachusetts
Medical School Worcester, Massachusetts 01655
Earl L. Parr
Department of Anatomy School of Medicine
Southern Illinois University Carbondale, Illinois 62901
Margaret B. Parr
Department of Anatomy School of Medicine
Southern Illinois University Carbondale, Illinois 62901
Elizabeth M. Ramsey
Department of Embryology Carnegie Institution of Washington
Baltimore, Maryland 21210
James C. Rose
Departments of Physiology and Obstetrics and Gynecology
Bowman Gray School of Medicine of Wake Forest University
Winston-Salem, North Carolina 27103
Melvyn S. Soloff
Department of Biochemistry Medical College of Ohio
Toledo, Ohio 43699
Michael P. Walsh
Department of Medical Biochemistry
University of Calgary Calgary, Alberta T2N 4N1, Canada
Ralph M. Wynn
Departments of Obstetrics and Gynecology and Anatomy and Cell Biology
Wayne State University School of Medicine
Detroit, Michigan 48201
Preface
Almost a quarter of a century has elapsed since Cellular Biology of the Uterus, the predecessor of the present volume, was planned. During that period, especially in the decade since the publication of the last edition of Biology of the Uterus, new information in the field has been so voluminous as to require major revisions of most of the chapters, the addition of several new chapters, and the collaboration of a second editor to facilitate the selection of appropriate experts as authors. As in prior editions, a balance has been struck between classical biology and modern biochemistry and biophysics. The inclusion of basic histological and embryo-logical information provides a necessary, though often lacking, background for the protein chemist and molecular biologist and a bridge between the cell biologist and clinician. Thus, major practical problems in human reproduction, such as the genesis of endometrial carcinoma and the cause of the initiation of labor, may be approached on a firm scientific footing.
The current edition deals primarily with the biology of the uterus itself (comparative and human) rather than placentation or pregnancy and thus is a synthesis of data derived from many techniques, both conventional and modern. As it is clearly beyond the competence of any one scientist to prepare such a text on the basis of personal knowledge and experience, the aid of 22 distinguished scientists was enlisted. All of these authors, acknowledged experts in their respective fields, agreed to extensive revisions of their chapters in the previous edition or preparation of entirely new contributions.
A scholarly history of uterine biology has been retained to illustrate the evolution of studies from superstition to speculation to science. The chapters on comparative anatomy and embryology of the human genitourinary tract have been revised by their original authors. It is noteworthy that Dr. Mossmans chapter was prepared on the occasion of that distinguished scientists 90th birthday. An extensively revised chapter on vascular anatomy and a new chapter on vascular physiology of the uterus, emphasizing the nonpregnant condition, precede the final 12 chapters, which stress cell biology. Comparative embryology of the mllerian derivatives provides the basis for predicting and analyzing the cellular response of the uterus to hormones. The chapters on vascular anatomy and physiology illustrate the dominant role of blood vessels in critical uterine functions such as menstruation and pregnancy, the effects on uterine blood flow of hormones, oxygenation, vasoactive amines, and prostaglandins, and the changes in uterine arteries as they relate to preeclampsia and retardation of intrauterine growth.
Two entirely new complementary chapters on biochemistry and cell biology of the endometrium bridge the gap between morphology and biochemistry and illustrate the crucial role of receptors in endocrine regulation of uterine activity. The cytoskeletal proteins, the biochemistry of the cellular surface, the extracellular matrix, and the secretory components of the endometrium are discussed as they relate to implantation and associated phenomena. The interrelations of the actions of steroid and peptide hormones, receptor status, synthesis of nucleic acids and proteins, and regulation of gene expression are detailed in one of the new pivotal chapters of this edition. The chapter on delayed implantation has been revised and extended to include a discussion of the uterus during early implantation, with detailed data derived from studies of marsupials and several orders of eutherian mammals. Delayed implantation strikingly illustrates the mediation of the developmental rate of one organism (the unimplanted blastocyst) by the internal environment (the uterus) of another. A new chapter on the implantation reaction discusses experimental techniques and hormonal sensitization of the endometrium for implantation. Contributions of electron microscopy to the understanding of several fundamental problems in reproductive biology are well documented. In particular, the role of prostaglandins in the initiation of decidualization and the importance of apoptosis as the mode of cellular death in uterine epithelium are discussed. A short but stimulating chapter on the role of stem cells in the regeneration of the primate uterus presents work currently in progress in the authors laboratory.
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