Hofmann Andreas - Wilson and Walkers Principles and Techniques of Biochemistry and Molecular Biology

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Andreas Hofmann and Samuel Clokie 2018

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Samuel Clokie and Andreas Hofmann

Parisa Amani and Andreas Hofmann

Anwar R. Baydoun

Ralph Rapley

Samuel Clokie

Ralph Rapley

Katja Fischer

John Grainger and Joanne Konkel

Robert J. Slater

Gill Rumsby

Stephen W. Paddock

Kay Ohlendieck and Stephen E. Harding

Anne Simon and Andreas Hofmann

Anne Simon and Joanne Macdonald

Sonja Hess and James I. MacRae

Cinzia Cantacessi and Anna V. Protasio

Paul Taylor

Tim J. Stevens

Jean-Baptiste Cazier

Pasi K. Korhonen and Robin B. Gasser

Sonja Hess and Michael Weiss

James I. MacRae

Megan Cross and Andreas Hofmann

David Camp

When the first edition of our book was published in 1975, biochemistry was emerging as a new discipline that had the potential to unify the previously divergent -ologies that constituted the biological sciences. It placed emphasis on the understanding of the structure, function and expression of individual proteins and their related genes, and relied on the application of analytical techniques such as electrophoresis, chromatography and various forms of spectrometry. In the ensuing 40 years the completion of the Human Genome Project has confirmed the central role of DNA in all of the activities of individual cells and the emergence of molecular biology as the means of understanding complex biological processes. This in turn has led to the new disciplines of bioinformatics, chemoinformatics, proteomics and metabolomics. The succeeding six editions of our book have attempted to reflect this evolution of biochemistry as a unifying discipline. All editions have placed emphasis on the experimental techniques that undergraduates can expect to encounter during the course of their university studies and to this end we have been grateful for the excellent feedback we have received from the users of the book.

The point has now been reached where we believed that it was appropriate for us to hand over the direction and academic balance of future editions to a new editorial team and to this end we are delighted that Andreas Hofmann and Samuel Clokie have agreed to take on the role. We wish them well and look forward to the continuing success of the book.

Keith Wilson and John Walker

It has been a tremendous honour being asked by Keith Wilson, John Walker and Cambridge University Press to take on the role of editorship for this eighth edition of Principles and Techniques . In designing the content, we extend the long and successful tradition of this text to introduce relevant methodologies in the biochemical sciences by uniquely integrating the theories and practices that drive the fields of biology, biotechnology and medicine. Methodologies have improved tremendously over the past ten years and new strategies and protocols that once were just applied by a few pioneering laboratories are now applied routinely, accompanied by ever more fluent boundaries between core disciplines leading to what is now called the life sciences.