F. A. Davis Company
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Philadelphia, PA 19103
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Copyright 2023 by F. A. Davis Company
Copyright 1988, 1991, 1993, 1995, 1997, 1999, 2001, 2003, 2005, 2007, 2009, 2011, 2013, 2015, 2017, 2019, 2021 by F. A. Davis Company. All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without written permission from the publisher.
Printed in the United States of America
Last digit indicates print number 10 9 8 7 6 5 4 3 2 1
Editor-in-Chief, Nursing: Jean Rodenberger
Acquisitions Editor: Lisa Houck
Content Project Manager: Amanda Minutola
NOTE : As new scientific information becomes available through basic and clinical research, recommended treatments and drug therapies undergo changes. The authors and publisher have done everything possible to make this book accurate, up to date, and in accord with accepted standards at the time of publication. However, the reader is advised always to check product information (package inserts) for changes and new information regarding dose and contraindications before administering any drug. Caution is especially urged when using new or infrequently ordered drugs.
Library of Congress Cataloging-in-Publication Data
Names: Vallerand, April Hazard, author. | Sanoski, Cynthia A., author.
Title: Daviss drug guide for nurses / April Hazard Vallerand, Cynthia A. Sanoski.
Other titles: Drug guide for nurses
Description: Eighteenth edition. | Philadelphia : F.A. Davis, [2023] | Includes bibliographical references and index.
Identifiers: LCCN 2022002509 (print) | LCCN 2022002510 (ebook) | ISBN 9781719646406 (paperback) | ISBN 9781719648110 (ebook)
Subjects: MESH: Pharmaceutical Preparations--administration & dosage | Drug Therapy--nursing | Pharmacology, Clinical--methods | Handbook | Nurses Instruction
Classification: LCC RM301.12 (print) | LCC RM301.12 (ebook) | NLM QV 735 | DDC 615.102/4613--dc23/eng/20220131
LC record available at https://lccn.loc.gov/2022002509
LC ebook record available at https://lccn.loc.gov/2022002510
Authorization to photocopy items for internal or personal use, of specific clients, is granted by F. A. Davis Company for users registered with the Copyright Clearance Center (CCC) Transactional Reporting Service, provided that the fee of $.25 per copy is paid directly to CCC, 222 Rosewood Drive, Danvers, MA 01923. For those organizations that have been granted a photocopy license by CCC, a separate system of payment has been arranged. The fee code for users of the Transactional Reporting Service is 978-1-7196-4640-6/22 0 (US) and 978-1-7196-4642-0/22 0 (Canadian) + $.25.
DEDICATION
To my son, Ben, whose sensitivity and sense of humor make even the toughest day easier.
To my daughter, Katharine, whose dedication and passion in seeking her goals I admire.
Watching you both grow to become wonderful young adults gives me such pride and joy. Your support of my work inspires me. Thank you for sharing so much of your lives with me. I love you.
AHV
To my wonderful mother and best friend, Geraldine, who has provided her continual love, support, and wisdom as I continue to pursue all of my personal and professional goals.
CAS
ACKNOWLEDGMENTS
We offer our thanks to the students and nurses who have used our book for more than 35 years. Wehope our book provides you with the current knowledge of pharmacotherapeutics you need to continue to give quality care in our rapidly changing health care environment.
April and Cindy
Contributors
Jamie Crawley, PhD, RN
Assistant Professor
University of Windsor
Faculty of Nursing
Windsor, ON, Canada
Wanda Edwards, PMHCNS-BC, NP
Instructor (Clinical)
Wayne State University
College of Nursing
Detroit, MI
Linda Felver, PhD, RN
Associate Professor
Oregon Health & Science University
School of Nursing
Portland, OR
Althea DuBose-Hayes, RDN
Consulting Renal Dietitian
Nephrology Associates of Michigan
Ann Arbor, MI
Margaret F. Galuardi, DNP, FNP-BC
Assistant Professor (Clinical)
Wayne State University College of Nursing
Detroit, Michigan
Jason Micheal Kiernan, PhD, RN, ACNP
Assistant Professor
Michigan State University, College of Nursing
East Lansing, Michigan
Debbie Richmond, NP-C, ACRN
Wayne State University
Detroit, MI
Gladdi Tomlinson, RN, MSN
Professor of Nursing
Harrisburg Area Community College
Harrisburg, PA
Sally Villasenor, DNP, RN, ACNP-BC
Assistant Professor (Clinical)
Wayne State University College of Nursing
Detroit, Michigan
Erin Ziegler, PhD, NP-PHC
Assistant Professor
Daphne Cockwell School of Nursing, Ryerson University
Toronto, Ontario
HOW TO USE DAVISS DRUG GUIDE FOR NURSES
Daviss Drug Guide for Nurses provides comprehensive, up-to-date drug information in well-organized, nursing-focused monographs. It also includes extensive supplemental material in 14 appendices, thoroughly addresses the issue of safe medication administration, and educates the reader about 50 different therapeutic classes of drugs. In this 18th edition, we have continued the tradition of focusing on safe medication administration by including Medication Safety Tools and even more information about health cares most vulnerable patients: children, the elderly, pregnant women, and breast feeding mothers. Look for more Pedi , Geri , OB , Lactation , and Rep headings in the monographs. We have also included a BEERS label at the top of applicable drug monographs for those medications listed in the Beers Criteria developed by the American Geriatrics Society. These medications are considered to be potentially inappropriate for use in older adults because they are associated with more risk than benefit in this patient population. In addition, weve included information relevant to Canadian students and nurses. Youll find an appendix comparing Canadian and U.S. pharmaceutical practices, more Canada-only combination drugs in the Combination Drugs appendix, and additional Canadian brand names in the drug monographs. To help you find this information quickly, weve also added a maple leaf icon () in the index next to each Canadian entry. We have added pharmacogenomic information throughout numerous monographs to guide the nurse in selecting and monitoring various drug therapies. To help you find this information quickly, weve added a double helix icon () to denote this information as it applies to specific drugs. Use this book to enhance your competence in implementing and evaluating medication therapies. The following sections describe the organization of Daviss Drug Guide for Nurses and explain how to quickly find the information you need.
Safe Medication Use Articles
Medication Errors: Improving Practices and Patient Safety, Detecting and Managing Adverse Drug Reactions, Overview of Risk Evaluation and Mitigation Systems (REMS), Special Dosing Considerations, and Educating Patients About Safe Medication Use comprise the safe medication use articles and provide an overview of the medication safety issues that confront practitioners and patients. Leading off this series, the medication errors article familiarizes you with the systems issues and clinical situations repeatedly implicated in medication errors and suggests practical means to avoid them. It also teaches you about
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