THE BIG PICTURE
MEDICAL PHYSIOLOGY
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MEDICAL PHYSIOLOGY
THE BIG PICTURE
Jonathan D. Kibble, PhD
Associate Professor
Faculty of Medicine
Memorial University
St. Johns, Newfoundland,
Canada
Colby R. Halsey, MD
Resident
Internal Medicine
Washington University Barnes-Jewish Hospital
St. Louis, Missouri
Copyright 2009 by The McGraw-Hill Companies, Inc. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher.
ISBN: 978-0-07-164302-3
MHID: 0-07-164302-8
The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-148567-8, MHID: 0-07-148567-8
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Cover image: Computer artwork of a nerve cell, also called a neuron. Neurons are responsible for passing information around the central nervous system (CNS) and from the CNS to the rest of the body. The nerve cell comprises a nerve cell body (center) surrounded by numerous extensions called dendrites, which collect information from other nerve cells or from sensory cells. Each neuron has one process called an axon through which information passes to other cells, including other nerve cells and muscle fibers.
Credit: Alfred Pasieka / Photo Researchers, Inc.
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DEDICATION
To my family for their love, support, and inspiration: my wife and soulmate, Vicki, and our wonderful boys, Sam and Thomas; my mum and dad, Sue and John; and my brother, Gary.
To my friend and mentor, Penny Hansen, for her wisdom; and to the students for their amazing energy and enthusiasm.
Jonathan D. Kibble
To my loving wife, Kathy, for her ever-present support and encouragement no matter what challenge lies in front of us; to my daughter, Katie, for always bringing sunshine and smiles to my life; to my mom and dad for leading by example; and to my good friend and classmate, Terry, for being the best study partner ever.
Colby R. Halsey
CONTENTS
PREFACE
The goal of this textbook is to help medical students efficiently learn and review physiology. The text offers a complete yet concise treatment of the major topics in medical physiology. Several design features are included to make the text easy to use.
High-yield clinical pearls, see followed by , are integrated throughout the text; clinical examples highlight the relevance and application of physiologic concepts.
Approximately 450 four-color figures illustrate essential processes; explanatory figure legends allow figures to be used for review.
Key concepts are highlighted in italics and basic terms are in bold when first mentioned.
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