Louis Theodore - A Guide to Virology for Engineers and Applied Scientists: Epidemiology, Emergency Management, and Optimization

1. Chapter 3
2. Chapter 4
3. Chapter 8
4. Chapter 11
5. Chapter 12
6. Chapter 13
7. Chapter 14
8. Chapter 16

1. Chapter 1
2. Chapter 2
3. Chapter 3
4. Chapter 6
5. Chapter 7
6. Chapter 8
7. Chapter 11
8. Chapter 12
9. Chapter 13
10. Chapter 14
11. Chapter 15
12. Chapter 16
13. Chapter 17

Megan M. Reynolds and Louis Theodore

This edition first published 2023
2023 John Wiley & Sons, Inc.

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The right of Megan M. Reynolds and Louis Theodore to be identified as the authors of this work has been asserted in accordance with law.

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Library of Congress CataloginginPublication Data applied for:
Hardback ISBN: 9781119853138

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Cover Image: Yuichiro Chino/Getty Images

TO
My father, Dr. Joseph P. Reynolds (MMR)

AND

My friends and colleagues working in the field of virology (LT)

When an epidemic of physical disease starts to spread, the community approves and joins in a quarantine of the patients in order to protect the health of the community against the spread of the disease

Franklin Delano Roosevelt (18821945)

As its title implies, this book offers a guide to virology which provides information on viruses from an engineer's and applied scientist's perspective. Concise and easy to use, this guide brings together a wealth of general information on viruses in one compact book. It additionally offers practical and technical information plus calculation details.

The guide has been written not only for students but also for those in technical roles, such as engineers and applied scientists who work in public health, pharmaceuticals, or other healthrelated fields. It is a tool that may be used whenever and wherever information about viruses is likely to be sought.

In the wake of the COVID19 pandemic, it has become evident that knowledge of virology is no longer critical only to doctors or epidemiologists; there is an urgent need for cooperation among varied disciplines to address the current pandemic and prepare for the next one. The authors feel that no one source currently covers all of the information on viruses in the manner presented in this book. It is hoped that this book will serve to fill the growing need for concise and digestible information both academically and professionally in these fields.

The guide is divided into three parts. provide information on practical/technical considerations and on calculation details, respectively. In addition, a number of illustrative examples are included for each chapter.

Reasonable care has been taken to ensure the accuracy of the information contained in this book. However, the authors and the publisher cannot be held responsible for erroneous omissions in the information presented or for any consequences arising from the use of the information published in the book. Accordingly, reference to original sources is encouraged. Reporting of any errors or omissions is solicited in order to ensure that appropriate changes may be made in future editions.

The authors wish to thank the following individuals for their important contributions to the work: Marybeth R. Radics, Mary K. Theodore, Ann Marie Flynn, and Matthew C. Ogwu.

Finally, the authors also wish to acknowledge the contributing authors: Sarah Forster (Overview of Molecular Biology), Emma Parente (Safety Protocols and Personal Protection Equipment), Vishal Bhatty (Engineering Principles and Fundamentals), Paul DiGaetano, Jr. (Ethical Considerations in Virology), and Julian Theodore (Introduction to Mathematical Methods).

Megan M. Reynolds, BS, MS, MBA, is a freelance medical writer and editor with a particular focus on infectious diseases. With degrees in chemical engineering, international business, and medicine, she worked in the pharmaceutical field in various capacities for more than a dozen years in both the United States and Europe. Her experience encompasses manufacturing, sales, and marketing from managing production scaleup for the launch of new drug manufacturing lines to spearheading an education initiative for healthcare providers at a large New York public hospital aimed at increasing vaccine utilization. She also studied methods for minimizing bacterial resistance due to the overuse of antibiotics. Previous publications include textbook chapter contributions, a case report on the successful treatment of a patient with a rare, highly resistant infection, as well as a medical narrative on treating patients in severe pain. Her recent research interests have focused on addressing the high rate of hospitalacquired infections leading to sepsis and on reducing vaccine hesitancy towards measles, mumps, and rubella vaccine (MMR). Raised in New York City, Ms. Reynolds is multilingual and has lived and worked in several countries, including Italy, Spain, and Germany, and has studied in the United States, Mexico, and Grenada. She is currently based in northern Italy and enjoys living in the Alps while pursuing her passions in rock climbing, yoga, and skiing.