Brian Fertig - Metabolism and Medicine: The Metabolic Landscape of Health and Disease

Metabolism and Medicine

This textbook series focuses on foundational principles and experimental approaches across all areas of biological physics, covering core subjects in a modern biophysics curriculum. Individual titles address such topics as molecular biophysics, statistical biophysics, molecular modeling, single-molecule biophysics, and chemical biophysics. It is aimed at advanced undergraduate- and graduate-level curricula at the intersection of biological and physical sciences. The goal of the series is to facilitate interdisciplinary research by training biologists and biochemists in quantitative aspects of modern biomedical research and to teach key biological principles to students in physical sciences and engineering.

Authors are also welcome to contact the publisher (Physics Editor, Carolina Antunes: ) to discuss new title ideas.

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Biomolecular Kinetics: A Step-by-Step Guide

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Biomolecular Thermodynamics: From Theory to Application

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Quantitative Understanding of Biosystems: An Introduction to Biophysics

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Quantitative Understanding of Biosystems: An Introduction to Biophysics, Second Edition

Thomas M. Nordlund, Peter M. Hoffmann

Entropy and Free Energy in Structural Biology: Thermodynamics, Statistical Mechanics And Computer Simulation

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Metabolism and Medicine: Two Volume Set

Brian Fertig

https://www.crcpress.com/Foundations-of-Biochemistry-and-Biophysics/book-series/CRCFOUBIOPHY

Metabolism and Medicine

The Metabolic Landscape of Health and Disease
Volume 2

Brian J. Fertig, M.D., F.A.C.E.

Associate Professor, Robert Wood Johnson Medical School
Chairman, Department of Diabetes & Endocrinology,
Hackensack Meridian Health @ JFK University Medical Center
Founder Diabetes & Osteoporosis Center, Piscataway, N.J.

First edition published 2022

by CRC Press

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and by CRC Press

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2022 Brian Fertig

CRC Press is an imprint of Taylor & Francis Group, LLC

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Library of Congress Cataloging-in-Publication Data

Names: Fertig, Brian, author.

Title: Metabolism and medicine / Brian Fertig, M.D., Robert Wood Johnson Medical School, Department of Diabetes & Endocrinology Hackensack Meridian, Health @ JFK University Medical Center.

Description: First edition. | Boca Raton : CRC Press, 2022. | Series: Foundation of biochemistry and biophysics | Includes bibliographical references and index.

Identifiers: LCCN 2021027983 (print) | LCCN 2021027984 (ebook) | ISBN 9780367699925 (hardback) | ISBN 9780367712297 (paperback) | ISBN 9781003149897 (ebook)

Subjects: LCSH: Metabolism--Disorders. | Human body--Microbiology.

Classification: LCC RC627.5 .F47 2022 (print) | LCC RC627.5 (ebook) | DDC 616.3/9--dc23

LC record available at https://lccn.loc.gov/2021027983

LC ebook record available at https://lccn.loc.gov/2021027984

ISBN: 9780367699925 (hbk)

ISBN: 9780367712297 (pbk)

ISBN: 9781003149897 (ebk)

DOI: 10.1201/9781003149897

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by Deanta Global Publishing Services, Chennai, India

There are numerous individuals to whom I owe a huge debt of gratitude for their assistance on this journey of discovery. I list and acknowledge their many positive effects on my development as a scientist and a writer, as well as their contributions to these two volumes.

First and foremost, my dynamic editorial team with multidisciplinary expertise did much of the heavy lifting needed to bring this project to completion. This amazing group of talented individuals was led by Gail Ferstandig Arnold, Ph.D. (Research Professor, Chemistry and Chemical Biology) who served as Associate Director, Graduate Studies and Academic Affairs as well as Associate Director, Institute for Quantitative Biomedicine (IQB), at Rutgers State University of New Jersey. Seeking editorial assistance through various Sections of the Science Division at Rutgers, I was referred to Gail in the IQB, and have had the pleasure of knowing her for about six or seven years. Gail should be credited for getting the ball moving towards the eventual amassment of an extraordinarily talented team of contributing editors. The process started with several graduate students who helped track down references for areas involving Volume 2. Moreover, Gail, upon her retirement from Rutgers, accepted my offer to personally apply her talented hand to the active editing of various important areas in Volume 2. Gail also has the essential skillset as an administrative coordinator. She has been vital for maintaining the coordinated activation of a robust team of editing and graphic design contributors. Gails attitude is inspirational, and I couldnt thank her enough for this.

A major role in compiling material for Volume 1 was played by Dr. Shashidhar Rao, who has impressive experience in the pharma industry. A physical chemist with a penchant for biological chemistry, Shashidhar became the first senior scientist recruited to the project, at Gails direction. Shashidhar Rao, a Rutgers scientist, was quite interested and capable of extending and assimilating his solid foundation of molecular chemistry to the realm of living systems. Shashi came on board about 6 years ago, helping with the revision of the Biological Thermodynamics Chapter in Volume 1. He taught me a lot about the dynamic chemistry of physical systems which is crucial for conveying analogies and relationships to living systems. Throughout the course of the ensuing years, his fastidious work ethic was valuable for proofreading and following up on missing elements. A couple of years later, Dr. Jack Tuszynski revisited the chapter to revise it to its current form. Shashidhar, always a gentleman, remained a loyal and stalwart partner, helping wherever he could, and has remained a strong contributor during the past six years.