Tanaka - Industrial Application of Immobilized Biocatalysts (Biotechnology and Bioprocessing Series)

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title	:	Industrial Application of Immobilized Biocatalysts Bioprocess Technology ; V. 16
author	:	Tanaka, Atsuo
publisher	:	CRC Press
isbn10 | asin	:	0824787447
print isbn13	:	9780824787448
ebook isbn13	:	9780585346038
language	:	English
subject	Bioreactors, Immobilized cells, Immobilized enzymes, Immobilized cell organelles.
publication date	:	1993
lcc	:	TP248.25.B55I53 1993eb
ddc	:	660/.63
subject	:	Bioreactors, Immobilized cells, Immobilized enzymes, Immobilized cell organelles.

Industrial Application of Immobilized Biocatalysts

BIOPROCESS TECHNOLOGY Series Editor W. Courtney McGregor Xoma Corporation Berkeley, California 1. Membrane Separations in Biotechnology, edited by W. Courtney McGregor 2. Commercial Production of Monoclonal Antibodies: A Guide for Scale-Up, edited by Sally S. Seaver 3. Handbook on Anaerobic Fermentations, edited by Larry E. Erickson and Daniel Yee-Chak Fung 4. Fermentation Process Development of Industrial Organisms, edited by Justin O. Neway 5. Yeast: Biotechnology and Biocatalysis, edited by Hubert Verachtert and Ren De Mot 6. Sensors in Bioprocess Control, edited by John V. Twork and Alexander M. Yacynych 7. Fundamentals of Protein Biotechnology, edited by Stanley Stein 8. Yeast Strain Selection, edited by Chandra J. Panchal 9. Separation Processes in Biotechnology, edited by Juan A. Asenjo 10. Large-Scale Mammalian Cell Culture Technology, edited by Anthony S. Lubiniecki 11. Extractive Bioconversions, edited by Bo Mattiasson and Olle Holst 12. Purification and Analysis of Recombinant Proteins, edited by Ramnath Seetharam and Satish K. Sharma 13. Drug Biotechnology Regulation: Scientific Basis and Practices, edited by Yuan-yuan H. Chiu and John L. Gueriguian 14. Protein Immobilization: Fundamentals and Applications, edited by Richard F. Taylor 15. Biosensor Principles and Applications, edited by Loc J. Blum and Pierre R. Coulet 16. Industrial Application of Immobilized Biocatalysts, edited by Atsuo Tanaka, Tetsuya Tosa, and Takeshi Kobayashi ADDITIONAL VOLUMES IN PREPARATION Insect Cell Culture Engineering, edited by M. F. A. Goosen, A. J. Daugulis, and P. Faulkner

Page i Industrial Application of Immobilized Biocatalysts Edited by Atsuo Tanaka Department of Industrial Chemistry Kyoto University Kyoto, Japan Tetsuya Tosa Research Laboratory of Applied Biochemistry Tanabe Seiyaku Co., Ltd. Osaka, Japan Takeshi Kobayashi Department of Biotechnology Nagoya University Nagoya, Japan

Page ii Library of Congress Cataloging-in-Publication Data Industrial application of immobilized biocatalysts / edited by Atsuo Tanaka, Tetsuya Tosa, Takeshi Kobayashi. p. cm. (Bioprocess technology; 16) Includes bibliographical references and index. ISBN 0-8247-8744-7 (alk. paper) 1. Bioreactors. 2. Immobilized cells. 3. Immobilized enzymes. I. Tanaka, Atsuo. II. Tosa, Tetsuya. III. Kobayashi, Takeshi. IV. Series. TP248.25.B55153 1993 660'.63dc20 92-23504 CIP This book is printed on acid-free paper. Copyright 1993 by MARCEL DEKKER, INC. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. MARCEL DEKKER, INC. 270 Madison Avenue, New York, New York 10016 Current printing (last digit): 10 9 8 7 6 5 4 3 2 1 PRINTED IN THE UNITED STATES OF AMERICA

Page iii SERIES INTRODUCTION Bioprocess technology encompasses all of the basic and applied sciences as well as the engineering required to fully exploit living systems and bring their products to the marketplace. The technology that develops is eventually expressed in various methodologies and types of equipment and instruments built up along a bioprocess stream. Typically in commercial production, the stream begins at the bioreactor, which can be a classical fermentor, a cell culture perfusion system, or an enzyme bioreactor. Then comes separation of the product from the living systems and/or their components followed by an appropriate number of purification steps. The stream ends with bioproduct finishing, formulation, and packaging. A given bioprocess stream may have some tributaries or outlets and may be overlaid with a variety of monitoring devices and control systems. As with any stream, it will both shape and be shaped with time. Documenting the evolutionary shaping of bioprocess technology is the purpose of this series. Now that several products from recombinant DNA and cell fusion techniques are on the market, the new era of bioprocess technology is well established and validated. Books of this series represent developments in various segments of bioprocessing that have paralleled progress in the life sciences. For obvious proprietary reasons, some developments in industry, although validated, may be published only later, if at all. Therefore, our continuing series will follow the growth of this field as it is available from both academia and industry.

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