Bradford C. Dickerson - Hodges’ Frontotemporal Dementia

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Library of Congress Cataloguing in Publication data

Hodges' frontotemporal dementia / edited by Bradford C. Dickerson. Second edition.

p. ; cm.

Frontotemporal dementia

Preceded by: Frontotemporal dementia syndromes / edited by John R. Hodges. 2007.

Includes bibliographical references and index.

ISBN 978-1-107-08663-0 (hardback)

I. Dickerson, Bradford C., editor. II. Frontotemporal dementia syndromes. Preceded by (work): III. Title: Frontotemporal dementia.

[DNLM: 1. Frontotemporal Dementia. WM 220]

RC521

616.83 dc23 2015010598

ISBN 978-1-107-08663-0 Hardback

Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate.

Every effort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors, and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors, and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use.

To all the individuals with illnesses who entrust their lives to me, their families and caregivers; I treasure our partnerships in the journeys we take as we try to make sense of living with these tragic diseases and do everything we can to fight back .

I dedicate this book to Dr. Leyla de Toledo-Morrell: pioneering neuroscientist, talented teacher, dedicated mentor, and loving friend and grandmother. Her passing in January 2015 left those of us lucky enough to know her with a deep hole in our lives .

John R. Hodges

Paul McMonagle and Andrew Kertesz

Matthew Jones and David Neary

Katya Rascovsky

Chiara Cerami and Stefano F. Cappa

Thomas H. Bak and Sharon Abrahams

Barbara Borroni and Antonella Alberici

Bradford C. Dickerson, Simon Ducharme, and Chiadi U. Onyike

Teresa Torralva, Macarena Martinez Cuitio, and Facundo Manes

Jonathan D. Rohrer

Nicolaas A. Verwey, Yolande A. L. Pijnenburg, and Philip Scheltens

Jill S. Goldman and Elisabeth McCarty Wood

Manuela Neumann, Gabor G. Kovacs, and Ian R. A. Mackenzie

Marc Cruts and Christine Van Broeckhoven

Brian A. Warmus and Erik D. Roberson

Claire M. O'Connor and Eneida Mioshi

Edward D. Huey and Masood Manoochehri

Richard M. Tsai and Adam L. Boxer

Susan Dickinson and Jill Shapira

Sharon Abrahams, PhD

Chair of Neuropsychology & Consultant Clinical Neuropsychologist, Department of Psychology & Euan MacDonald Centre for MND Research at the University of Edinburgh, UK

Antonella Alberici, MD

Neurologist, Centre for Neurodegenerative Disorders, Neurology Unit, University of Brescia, Brescia, Italy

Thomas H. Bak, MD

Department of Psychology & Euan MacDonald Centre for MND Research at the University of Edinburgh, UK

Barbara Borroni, MD

Associate Professor of Neurology, Centre for Neurodegenerative Disorders, Neurology Unit, University of Brescia, Brescia, Italy

Adam L. Boxer, MD PhD

Associate Professor of Neurology at the Department of Neurology, University of California, San Francisco, CA, USA

Stefano F. Cappa, MD

Professor of Neuropsychology at the Vita-Salute San Raffaele University and Director of the Neurology Department of San Raffaele Turro Hospital, Milan, Italy

Chiara Cerami, MD

Neurologist and Research Fellow, Vita-Salute San Raffaele University and San Raffaele Hospital, Milan, Italy

Marc Cruts, PhD

Associate Professor at University of Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge; Senior Staff Scientist in the Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Belgium

Bradford C. Dickerson, MD

Associate Professor of Neurology at Harvard Medical School, Boston, Director, Frontotemporal Disorders Unit, Co-investigator, Alzheimer's Disease Research Center, and Tom Rickles Endowed Chair in Primary Progressive Aphasia, Massachusetts General Hospital, Charlestown, MA, USA