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Reinhold Munker - Modern hematology: biology and clinical management

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Reinhold Munker and his distinguished colleagues offer a concise up-to-date summary of the fundamentals of clinical hematology, including all the most recent developments. Their comprehensive survey presents the essential clinical facts concerning malignant and nonmalignant blood diseases, detailing diagnostic methods, angiostatic drugs, the very latest therapies (e.g., stem cell transplantation), classifications, scientific controversies, and clear treatment recommendations. They also illuminate the scientific basis needed to understand the new diagnostic and treatment methodologies, the molecular pathogenesis of many hematologic disorders, and the new cellular therapies for these malignant disorders. By concisely combining cutting-edge explanations of disease pathophysiology with practical approaches to the diagnosis and management of hematologic disorders, Modern Hematology: Biology and Clinical Management provides an invaluable vade mecum for todays physicians and students needing to keep up with the latest clinical and scientific developments.

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title Modern Hematology Biology and Clinical Management Contemporary - photo 1

title:Modern Hematology : Biology and Clinical Management Contemporary Hematology
author:Munker, Reinhold.; Hiller, Erhard.; Paquette, Ronald
publisher:Humana Press
isbn10 | asin:0896036871
print isbn13:9780896036871
ebook isbn13:9780585387918
language:English
subjectHematologic Diseases, Hematologic Neoplasms.
publication date:2000
lcc:RC633.M866 2000eb
ddc:616.1/5
subject:Hematologic Diseases, Hematologic Neoplasms.
Page i
Modern Hematology
Page ii
CONTEMPORARY HEMATOLOGY
Modern Hematology: Biology and Clinical Management
by Reinhold Munker, Erhard Hiller, and Ronald Paquette, 2000
Red Cell Transfusion: APractical Guide
edited by Marion E. Reid and Sandra J. Nance, 1998
Page iii
Modern Hematology
Biology and Clinical Management
Reinhold Munker, MD
University of Munich
Munich, Germany
Erhard Hiller, MD
University of Munich/Klinikum Grohadern
Munich, Germany
Ronald Paquette, MD
School of Medicine
University of California, Los Angeles
Los Angeles, California
Foreword by
H. Phillip Koeffler, MD
UCLA Cedars-Sinai Medical Center
Los Angeles, CA
Page iv 2000 Humana Press Inc 999 Riverview Drive Suite 208 Totowa New - photo 2
Page iv
2000 Humana Press Inc.
999 Riverview Drive, Suite 208
Totowa, New Jersey 07512
All rights reserved.
No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher.
All authored papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher.
Due diligence has been taken by the publishers, editors, and authors of this book to assure the accuracy of the information published and to describe generally accepted practices. The contributors herein have carefully checked to ensure that the drug selections and dosages set forth in this text are accurate and in accord with the standards accepted at the time of publication. Notwithstanding, as new research, changes in government regulations, and knowledge from clinical experience relating to drug therapy and drug reactions constantly occurs, the reader is advised to check the product information provided by the manufacturer of each drug for any change in dosages or for additional warnings and contraindications. This is of utmost importance when the recommended drug herein is a new or infrequently used drug. It is the responsibility of the treating physician to determine dosages and treatment strategies for individual patients. Further it is the responsibility of the health care provider to ascertain the Food and Drug Administration status of each drug or device used in their clinical practice. The publisher, editors, and authors are not responsible for errors or omissions or for any consequences from the application of the information presented in this book and make no warranty. express or implied, with respect to the contents in this publication.
This publication is printed on acid-free paper.
ANSI Z39.48-1984 (American Standards Institute) Permanence of Paper for Printed Library Materials.
Cover design by Patricia F. Cleary.
Cover illustration: Figure 5.2., Color Plate I (following p. 180), pernicious anemia (bone marrow aspirate with megaloblastic erythropoiesis, large erythroblasts with immature nuclei).
For additional copies, pricing for bulk purchases, and/or information about other Humana titles, contact Humana at the above address or at any of the following numbers: Tel: 973-256-1699: Fax: 973-256-8341; E-mail: humana@humanapr.com, or visit our Website at www.humanapress.com
Photocopy Authorization Policy:
Authorization to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by Humana Press Inc., provided that the base fee of US $10.00 per copy, plus US $00.25 per page, is paid directly to the Copyright Clearance Center at 222 Rosewood Drive, Danvers, MA 01923. For those organizations that have been granted a photocopy license from the CCC, a separate system of payment has been arranged and is acceptable to Humana Press Inc. The fee code for users of the Transactional Reporting Service is: [0-89603-687-1/00 $10.00 + $00.25].
Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1
Library of Congress Cataloging-in-Publication Data
Munker, Reinhold.
Modern hematology: biology and clinical management / Reinhold Munker, Erhard Hiller, Ronald Paquette.
p. cm.--(Contemporary hematology)
Includes bibliographical references and index.
ISBN 0-89603-687-1 (alk. paper)
1. Blood--Diseases. 2. Hematology. I. Hiller, Erhard. II. Paquette, Ronald, 1958 III. Title. IV. Series.
[DNLM: 1. Hematologic Diseases. 2. Hematologic Neoplasms. WH 120 M966m 2000]
RC633.M866 2000
616.1'5--dc21
99-049377
Page v
Foreword
The modern practice of hematology requires not only clinical acumen but also an understanding of cellular physiology, immunology, and molecular biology. Recent advances have elucidated the molecular pathogenesis of many hematologic disorders and have led to the development of new diagnostic methodologies. In addition, the use of monoclonal antibodies has revolutionized the classification of hematologic malignancies.
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