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Howard I. Maibach (editor) - Chemical Skin Injury: Mechanisms, Prevention, Decontamination, Treatment

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Howard I. Maibach (editor) Chemical Skin Injury: Mechanisms, Prevention, Decontamination, Treatment

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This book provides an up-to-date, compact but comprehensive review of chemical skin injuries, differentiating them from thermal skin burns. After an introductory chapter on the history of chemical skin injuries and the scope of the problem, the anatomy, histology, physiology, and immunology of normal skin are described. Mechanisms involved in chemical penetration of normal skin are explained, and the effects of damaged skin on chemical penetration are analyzed. The remainder of the book discusses a variety of clinically relevant aspects, such as the different forms of chemical skin injury, including injuries that arise during skin peeling or due to hair products; preventive measures; emergency treatment; rinsing therapy; medical and surgical treatment; and the importance of providing relevant information to workers. The role of predictive toxicology is also considered.

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Springer-Verlag Berlin Heidelberg 2014
Howard I. Maibach and Alan H. Hall (eds.) Chemical Skin Injury 10.1007/978-3-642-39779-0_1
1. History of Chemical Burns and Scope of the Problem
Patrice Josset 1, 2
(1)
Department of Pathology, Hopital dEnfants Armand Trousseau, Paris, France
(2)
Director of the Teaching Program of the History of Medicine, University of Pierre and Marie Curie, 2 Avenue de la Gare, Villenauxe la grande, 10370 Paris, France
(3)
Toxicology Consulting and Medical Translating Services, 728, Azle, TX 76098-0728, USA
(4)
Colorado School of Public Health, University of Colorado-Denver, Denver, CO, USA
Patrice Josset (Corresponding author)
Email:
Alan H. Hall (Corresponding author)
Email:
1.1
1.1.1
1.1.2
1.1.3
1.2
1.2.1
1.2.2
1.2.3
1.1 History of Chemical Burns: Introduction
1.1.1 Introduction
Patrice Josset 5, 6
(5)
Department of Pathology, Hopital dEnfants Armand Trousseau, Paris, France
(6)
Director of the Teaching Program of the History of Medicine, University of Pierre and Marie Curie, 2 Avenue de la Gare Villenauxe la grande, 10370 Paris, France
Describing the history of chemical burns from antiquity to today presents some difficulties. The first, and most important, rests on the recent concepts of acids and bases.
Some products we now recognize as acidic or basic were used in ancient times but without knowing their specific chemical properties. But more importantly, at that ancient time, strong acids or bases did not exist at all. This is the second major difficulty. However, do not exclude that, on the occasion, some may have been accidentally produced.
1.1.2 From Antiquity to the Renaissance
The ancient authors (Hippocrates, Galen, Celsius, as well as Pliny the Elder) furnish meager indications on products, of which we are aware today, having the nature of being acidic or basic. However, they have not been recognized for a long time. In any case, the ancient physicians treated such injuries with water lavage or rinsing with other liquids. One can find in the Natural History of Pliny the Elder comments or hints about certain acidic or basic products. As well, Pliny gives some hints as to salts utilized not only by the Egyptians but also by oriental peoples for their utility in medicine, cooking, and glass manufacturing. It can be remarked that workers who collected salt had few effects, but that their shoes were damaged. The product was most certainly gregariously utilized by the Byzantines and which assured them for several centuries a true superiority over their Arabic bellicose neighbors. It seems these gregarious issues contributed to the assurance of the supremacy of the Byzantines over their arch Arab rivals for several centuries. It is unusual that an Army has changed the course of history unless it guarded a secret and assured long-lasting supremacy.
1.1.3 Modern and Contemporary Times
1.1.3.1 The Invention of Strong Acids and Bases
Chemistry is a science of which the theories have only lately been established (in the 1800s to the 1900s). It has been preceded by many centuries of human activities in many domains in such fields as archeology, but above all, certain writings which have come to restore knowledge that might have remained unknown to us.
The ancient Greek and Alexandrian alchemists made many original discoveries, but their acceptance into Greek and Arabic science was at a time of particular inspirations. It was in this way that the alchemist Jabbar ibn Hayyan, known in the Persian West under the name of Geber, originally made the discovery of hydrochloric and nitric acids among many memorable discoveries at the end of the eighth century.
Hydrochloric acid was known in Europe during the Middle Ages under the name of spirits of salt. The industrial production of this acid developed as a by-product of the manufacture of alkalis, notably of calcium carbonate. Nitric acid was utilized by Albert le Grand to separate gold from silver. Lavoisier showed that nitric acid contained hydrogen and nitrogen. Industrial manufacturing commenced in the nineteenth century, by diverse methods which allowed lower and lower costs.
Sulfuric acids were known under the names of vedriol and vitriol since the eleventh century. It was well known to alchemists who attributed to it the symbol of the green lion (Fig. ). Moreover, one sees the successful use of vitriol in criminality in the nineteenth century and later.
Fig 11 The green lion alchemistic symbol for vitriol engraving by Thodore - photo 1
Fig. 1.1
The green lion: alchemistic symbol for vitriol, engraving by Thodore de Bry illustrating the Atalantis Fugiens of Albert Maier
The discovery of bases is also very ancient. In prehistorical times, plants were utilized because they could be made into soaps. They had to be burned, and the cinders could be made into soaps, such as Marseille soaps or Aleppo soap, depending on where they were made. The plants alkaline properties, whether the species were Salicornia or simply common soda ( Salsola soda [), define the properties that allow soaps to be made.
Fig 12 Salsola soda 2006 Rignanese From the vegetal soda sodium - photo 2
Fig. 1.2
Salsola soda (2006 Rignanese [])
From the vegetal soda (sodium carbonate) caustic soda (sodium hydroxide) was obtained through the process of caustification. The process was improved by Nicolas Lebanc (1791) and Ernest Solvay (1861) who obtained sodium hydroxide by the electrolysis of sodium chloride.
As we noted the discovery of acids and strong bases has often preceded, by one or two millennia, their industrial manufacturing.
Accidental exposures to such products themselves have been limited and confined to alchemists, scholars, and other researchers and eventually as well to those with other expertise. However, the manufacture in ton batches in place of gram amounts and the exposure of large numbers of workers to strong acids and bases are implicit in numerous industrial chemical processes. It thus remains possible that chemical splashes with these products might be abundant.
1.1.3.2 Accidents and Attacks
Once they were scientifically discovered, strong acids and bases were rapidly adapted into the areas of warfare and criminal attacks. As such, during the course of the nineteenth and twentieth centuries, it is possible to observe the effects of these products in domestic or industrial accidents, as well as in personal attacks with acids and bases and in wartime with toxic gases in combat.
It is notable that many criminal actions have been based on the use of chemical products, such as the Tokyo attack by the Aum sect, as well as the atrocities under the Nazi regime.
Attacks with Acids or Vitriol
Assaults with vitriol were popularized in the newspapers in the nineteenth century. Among the authors who played a role in these, Alexandre Dumas had some heroes and heroines who were capable of doing so [].
During the middle portion of the nineteenth century, acid attacks were mostly done by women who did not require the strength necessary to use knives or revolvers (these were more difficult to obtain than a bottle of acid). In the twentieth century, we saw the emergence of chemical attacks by men against women in the third-world and developing countries, India, Pakistan, and Bangladesh, but also in other Asian and African countries. It is interesting to note that the attention brought to bear for the victims is a rather recent development and some associations have begun to assist them because they bear the burdens of social disapproval and disfiguration. The Acid Survivors Foundation in Bangladesh), but there exist other associations in the world which merit generous consideration.
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