Geraldine ODowd - Wheaters Pathology: A Text, Atlas and Review of Histopathology

2020, Elsevier Ltd. All rights reserved.

First edition 1985

Second edition 1991

Third edition 1996

Fourth edition 2003

Fifth edition 2010

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This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). The right of Geraldine ODowd, Sarah Bell, and Sylvia Wright to be identified as authors of this work has been asserted by them in accordance with the Copyright, Designs and Patents Act 1988.

ISBN: 978-0-7020-7559-9

eBook ISBN: 978-0-7020-7555-1

International ISBN: 978-0-7020-7560-5

Content Strategist: Alexandra Mortimer

Content Development Specialist: Trinity Hutton

Project Manager: Julie Taylor

Design: Miles Hitchen

Illustration Manager: Muthu Thangaraj

Marketing Manager: Michele Milano

Printed in China

Last digit is the print number: 9 8 7 6 5 4 3 2 1

As we set out to write this new edition of Wheaters Pathology, our aspirations were two-fold. We wished to retain the clarity and simplicity of the existing text, supported by high quality photomicrographs, in order to provide a solid introduction for beginners in pathology and to illustrate key features of major pathological processes and diseases for slightly more advanced trainees, either in pathology or in other specialities. Alongside this, we were aware of the need to update some aspects of the text (such as classification systems and molecular diagnostic techniques), to expand other areas (such as the clinical textboxes which were added in the previous edition) and, where appropriate, to provide additional content such as macroscopic images and normal histology for comparison. It has been possible to incorporate many of these features in the printed textbook without greatly increasing its original size. However, the addition of new electronic platforms has provided us with the opportunity to expand the available educational content considerably, without the risk of producing an immense and unwieldy tome. Throughout this new edition, we have provided links to a range of online materials: normal histology images from Wheaters Functional Histology; a large number of high quality macroscopic pathology images of common pathological processes (kindly provided by Professor Robin Cooke); some additional clinical, histological and molecular data where appropriate; and also a bank of self-assessment questions to accompany each chapter.

Two new authors have joined us for the production of this edition. Our colleague of many years, Dr Barbara Young, has recently retired following her career-long involvement in the Wheaters series and Dr Willie Stewart has left the team to pursue his considerable commitments in other areas. We wish them well in their new endeavours. Our new authors, Dr Sarah Bell and Dr Sylvia Wright, have brought great energy and drive to this new production, as well as their considerable knowledge in rapidly evolving fields such as molecular pathology.

Although the general format of this new edition remains broadly similar, it has been thoroughly updated throughout. We have added a new introductory chapter covering basic histology techniques, as well as the principles of immunohistochemistry, molecular testing and digital pathology. Some chapters have been completely revised, whilst others include less comprehensive but important updates and further clinical and molecular textboxes. Throughout, we have inserted links cross-referencing additional online material, including normal histology images for comparison (from the companion text Wheaters Functional Histology, denoted E-Fig. X.XH), gross images of common disorders (kindly used with the permission of Professor Robin Cooke, denoted E-Fig. X.XG) and some further clinical, molecular and histological online content. We hope that the revised end of chapter reviews, as well as our new bank of self-assessment questions, will be helpful revision aids.