Matthew A. Wallig et al. - Fundamentals of Toxicologic Pathology
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- Book:Fundamentals of Toxicologic Pathology
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Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development.
The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others.
- Presents revised and updated information for each chapter on systems
- Contains expanded sections on applied toxicologic pathology
- Includes the essential information necessary to understand toxicologic pathology in an accessible language
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- Tables in Chapter 1
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Third Edition
Edited by
Matthew A. Wallig
University of Illinois at Urbana-Champaign, Urbana, IL, United States
Wanda M. Haschek
University of Illinois at Urbana-Champaign, Urbana, IL, United States
Colin G. Rousseaux
University of Ottawa, Ottawa, ON, Canada
Brad Bolon
GEMpath Inc., Longmont, CO, United States
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Copyright 2018 Elsevier Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publishers permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Library of Congress Cataloging-in-Publication Data
A catalog record for this book is available from the Library of Congress
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
ISBN: 978-0-12-809841-7
For Information on all Academic Press publications visit our website at https://www.elsevier.com/books-and-journals
Publisher: Mica Haley
Acquisition Editor: Rob Sykes
Editorial Project Manager: Fenton Coulthurst
Production Project Manager: Anusha Sambamoorthy
Cover Designer: Mark Rogers
Typeset by MPS Limited, Chennai, India
To teach is to learn Japanese Proverb
We are profoundly grateful to those individuals responsible for our love of pathology and who mentored us during our careers as well as to our colleagues and students who inspired and supported us along this journey.
We also thank our partners, who encouraged and sustained us during our efforts to complete this revision.
Carl L. Alden , Mayflower Consulting, Wrenceburg, IN, United States
Brian R. Berridge , GlaxoSmithKline Research & Development, King of Prussia, PA, United States
Brad Bolon , GEMpath, Inc., Longmont, CO, United States
Denise I. Bounous , Bristol-Myers Squibb Co., Princeton, NJ, United States
Mark T. Butt , Tox Path Specialists, LLC, Frederick, MD, United States
Russell C. Cattley , Auburn University, Auburn, AL, United States
Robert E. Chapin , Retired, Pfizer Global R&D, Groton, CT, United States
Sandrine F. Chebekoue , University of Montreal, Montreal, QC, Canada
Dianne M. Creasy , Dianne Creasy Consulting, Norfolk, United Kingdom
John M. Cullen , North Carolina State University, Raleigh, NC, United States
Dimitry M. Danilenko , Genentech, South San Francisco, CA, United States
Barbara Davis , Innogenics, Inc., Harvard, MA, United States
Kelly L. Diegel , GlaxoSmithKline Research & Development, King of Prussia, PA, United States
David C. Dorman , North Carolina State University, Raleigh, NC, United States
Richard R. Dubielzig , University of Wisconsin-Madison, Madison, WI, United States
Susan A. Elmore , National Toxicology Program/NIEHS, Research Triangle Park, NC, United States
Suzanne E. Fenton , National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States
Duncan C. Ferguson , University of Illinois at Urbana-Champaign, Urbana, IL, United States
George L. Foley , Abbvie, Chicago, IL, United States
Robert H. Garman , Consultants in Veterinary Pathology, Inc., Murrysville, PA, United States
Kathryn E. Gropp , Pfizer Inc., Groton, CT, United States
Diane Gunson , Novartis Pharmaceuticals Corporation, East Hanover, NJ, United States
Gordon C. Hard , Toxicologic Pathology Consulting, Tairua, New Zealand
Jack R. Harkema , Michigan State University, East Lansing, MI, United States
Wanda M. Haschek , University of Illinois at Urbana-Champaign, Urbana, IL, United States
Eugene Herman , National Cancer Institute, Bethesda, MD, United States
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