Editors
Haijun Zhou , Charles C. Guo and Jae Y. Ro
Urinary Bladder Pathology
1st ed. 2021
Logo of the publisher
Editors
Haijun Zhou
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA
Weill Cornell Medical College, Houston Methodist, Houston, TX, USA
Charles C. Guo
Department of Pathology, MD Anderson Cancer Center, Houston, TX, USA
Jae Y. Ro
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA
Weill Cornell Medical College, Houston Methodist, Houston, TX, USA
ISBN 978-3-030-71508-3 e-ISBN 978-3-030-71509-0
https://doi.org/10.1007/978-3-030-71509-0
Springer Nature Switzerland AG 2021
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To my wife Catherine and our daughters Ava and Olivia for their support and love!
Haijun Zhou, MD, PhD
To my loving wife Cathy and my wonderful son Brian.
Charles C. Guo, MD
To my wife Jungsil and my sons family (Bobby, Kim, Avery, and Christian) for their love and support!
Jae Y. Ro, MD, PhD
Preface
Bladder diseases are common in clinical practice. While many inflammatory conditions and other abnormalities are usually managed clinically, tissue diagnosis is often needed if neoplastic lesions or non-neoplastic tumoral conditions are suspected. Bladder cancer is one of the top ten most common cancers in the United States (fourth in men and twelfth in women). Accurate diagnosis of bladder cancer plays a central role in daily pathology practice, clinical management, and prognosis. The variety of tumor histologic types and corresponding mimickers complicate bladder cancer pathologic diagnosis. Familiarity with common and uncommon bladder pathologic entities is vital for successful diagnosis of bladder cancers and subsequent patient management.
The focus of this book is bladder cancer pathology, including primary bladder malignancies and other tumor varieties involving the bladder, with an emphasis on diagnostic pitfalls and clinical relevance. This book also describes normal bladder histology, benign abnormalities with cancer mimickers, and cancer carcinogenesis important subject matter for understanding bladder cancers, correct diagnosis, and differential diagnoses. Advances in immunohistochemistry and molecular pathology have enhanced the accuracy of cancer pathology diagnoses. In addition to covering the anatomic and histologic features of bladder tumors, this book also reviews recent molecular and immunohistochemical advances in these areas. Recently updated clinical management information is also presented in this book.
Many experienced genitourinary pathologists, surgical pathologists, molecular pathologists, and clinical oncologists have contributed to this book, in addition to many fellows and residents.
We hope this book will be a useful resource for practicing pathologists, pathology trainees, and other health professionals who treat patients with bladder cancers.
Haijun Zhou
Charles C. Guo
Jae Y. Ro
Houston, TX, USA Houston, TX, USA Houston, TX, USA
Acknowledgment
This book is a result of teamwork with tremendous help and support from numerous colleagues. We thank our trainees and colleagues for providing insights in our practice of diagnostic genitourinary pathology and acknowledge the clinical teams in taking care of bladder cancer patients with their expertise and passion.
We would like to thank Adrienne Winston and Sasha Pejerrey for their assistance with scientific and editorial working in the preparation of our book.
Contents
Haijun Zhou , Charles C. Guo and Jae Y. Ro
Ziad M. El-Zaatari and Jae Y. Ro
Gang Wang
Haijun Zhou , Charles C. Guo and Jae Y. Ro
Charles C. Guo , Jae Y. Ro and Bogdan Czerniak
Kyung En Park , Qihui Jim Zhai and Fang-Ming Deng
Kosuke Miyai , Hussam Abu-Farsakh and Jae Y. Ro
Michael J. Hwang and Pheroze Tamboli
Ahmed N. Shehabeldin and Jae Y. Ro
Jie Xu , Shaoying Li and M. James You
Miao Zhang
Haijun Zhou
Qihui Jim Zhai and Fang-Ming Deng
Dilek Ertoy Baydar
Dalsan You , Bumjin Lim and Choung-Soo Kim
Omar Alhalabi and Jianjun Gao
Yong Mee Cho and Jae Y. Ro
Euno Choi , Sanghui Park and Jae Y. Ro
Haijun Zhou , Charles C. Guo and Jae Y. Ro
Contributors
Hussam Abu-Farsakh MD, FCAP
Department of Pathology, First Medical Lab, Amman, Jordan
Omar Alhalabi MD
Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Dilek Ertoy Baydar MD
Department of Pathology, Koc University Hospital, Istanbul, Turkey
Yong Mee Cho MD, PhD
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
Euno Choi MD
Department of Pathology, Ewha Womans University/Mok-dong Hospital, Seoul, South Korea
Bogdan Czerniak MD, PhD
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Fang-Ming Deng MD, PhD
Department of Pathology, New York University Langone Health, New York, NY, USA
Ziad M. El-Zaatari MD
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA
Jianjun Gao MD, PhD
Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Charles C. Guo MD
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Michael J. Hwang MD, PhD