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Phillip L. Williams - Principles of Toxicology: Environmental and Industrial Applications

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A fully updated and expanded edition of the bestselling guide on toxicology and its practical application * Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards * New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology * Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems * Includes case histories and examples from industry demonstrate the application of toxicological principles * Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms

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CONTENTS LIST OF TABLES Chapter 01 Chapter 02 Chapter 03 Chapter 05 - photo 1
CONTENTS
LIST OF TABLES
  1. Chapter 01
  2. Chapter 02
  3. Chapter 03
  4. Chapter 05
  5. Chapter 06
  6. Chapter 07
  7. Chapter 08
  8. Chapter 09
  9. Chapter 10
  10. Chapter 11
  11. Chapter 12
  12. Chapter 13
  13. Chapter 14
  14. Chapter 15
  15. Chapter 16
  16. Chapter 17
  17. Chapter 18
  18. Chapter 19
  19. Chapter 20
  20. Chapter 21
  21. Chapter 22
  22. Chapter 23
LIST OF ILLUSTRATIONS
  1. Chapter 01
  2. Chapter 02
  3. Chapter 03
  4. Chapter 04
  5. Chapter 06
  6. Chapter 07
  7. Chapter 08
  8. Chapter 09
  9. Chapter 10
  10. Chapter 11
  11. Chapter 12
  12. Chapter 13
  13. Chapter 14
  14. Chapter 15
  15. Chapter 17
  16. Chapter 19
  17. Chapter 20
  18. Chapter 21
  19. Chapter 22
  20. Chapter 23
Guide
Pages
PRINCIPLES OF TOXICOLOGY

Environmental and Industrial Applications

Third Edition

Edited By

STEPHEN M. ROBERTS

Professor and Program Director,

Center for Environmental & Human Toxicology,

University of Florida,

Gainesville, FL

ROBERT C. JAMES

Senior Principal Scientist,

ToxStrategies, Inc.,

Boise, ID

PHILLIP L. WILLIAMS

Dean, College of Public Health and Georgia Power Professor of Environmental Health Science,

University of Georgia,

Athens, GA

Copyright 2015 by John Wiley Sons Inc All rights reserved Published by John - photo 2

Copyright 2015 by John Wiley & Sons, Inc. All rights reserved

Published by John Wiley & Sons, Inc., Hoboken, New Jersey
Published simultaneously in Canada

No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 750-4470, or on the web at www.copyright.com. Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) 748-6011, fax (201) 748-6008, or online at http://www.wiley.com/go/permissions.

Limit of Liability/Disclaimer of Warranty: While the publisher and author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

For general information on our other products and services or for technical support, please contact our Customer Care Department within the United States at (800) 762-2974, outside the United States at (317) 572-3993 or fax (317) 572-4002.

Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic formats. For more information about Wiley products, visit our web site at www.wiley.com.

Library of Congress Cataloging-in-Publication Data:

Principles of toxicology : environmental and industrial applications / [edited by] Stephen M Roberts, Robert C James, Phillip L Williams. Third edition.
pagescm
Includes index.

ISBN 978-0-470-90791-7 (cloth)
1.Toxicology.2.Industrial toxicology.3.Environmental toxicology.I.Williams, Phillip L., 1952-II.James, Robert C.III.Roberts, Stephen M., 1950
RA1211.P746 2014
615.902dc23

2014020557

CONTRIBUTORS

T. Rene Anthony, Ph.D., Associate Professor, Department of Occupational and Environmental Health, University of Iowa, University of Iowa, College of Public Health, Iowa City, IA

Lisa A. Bailey, Ph.D., Senior Health Scientist, Gradient, Cambridge, MA

Barbara D. Beck, Ph.D., DABT, FATS, Principal, Gradient, Cambridge, MA

Michael S. Bloom, Ph.D., Associate Professor, Departments of Environmental Health Sciences and Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer, NY

Janice Britt, Ph.D., Senior Managing Scientist, ToxStrategies, Inc., Tallahassee, FL

Brenda S. Buikema, M.D., M.P.H, Assistant Professor (Clinical), Department of Occupational and Environmental Health, University of Iowa, College of Public Health; and Division of Pulmonary, Department of Internal Medicine, Critical Care, and Occupational Medicine, University of Iowa, Carver College of Medicine, Iowa City, IA

William M. Caudle, Ph.D., Assistant Professor, Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA

Harvey J. Clewell III, Ph.D., DABT, Director, Center for Human Health Assessment, Hamner Institute for Health Sciences, Research Triangle Park, NC

Rebecca A. Clewell, Ph.D., Hamner Institute for Health Sciences, Research Triangle Park, NC

Mary Jane Cunningham, Ph.D., Founder and President, Nanomics Biosciences, Inc., The Woodlands, TX

Steve Diamond, Ph.D., Vice President, Mid-West Division, Nanosafe, Duluth, MN

Michael R. Franklin, Ph.D., Professor, Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT

Michele M. Garber, M.P.H., Senior Scientist, Hazardous Substance & Waste Management Research, Tallahassee, FL

Vincent F. Garry, M.D., MS., DABT, Professor (Emeritus), Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

FredricGerr, M.D., Professor of Occupational and Environmental Health and Professor of Epidemiology, University of Iowa, College of Public Health; Iowa City, IA

Sherilyn A. Gross, Ph.D., Senior Health Scientist, Cardno ChemRisk Inc., Boulder, CO

Robert H. Heflich, Ph.D., U.S. Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR

Georgia Hinkley, Ph.D., Research Associate, Center for Environmental & Human Toxicology, University of Florida, Gainesville, FL

Mary L. Hixon, Ph.D., Senior Toxicologist, Gradient Corporation, Cambridge, MA

Keith A. Houck, Ph.D., Principal Investigator, National Center for Computational Toxicology, Office of Research & Development, U.S. Environmental Protection Agency, Research Triangle Park, NC

Robert C. James, Ph.D., Senior Principal Scientist, ToxStrategies, Inc., Boise, ID

Richard S. Judson, Ph.D., Principal Investigator, National Center for Computational Toxicology, Office of Research & Development, U.S. Environmental Protection Agency, Research Triangle Park, NC

James E. Klaunig, Ph.D., Professor, Department of Environmental Health, Indiana University, Ellettsville, IN

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