James E. Ferrell - Systems Biology of Cell Signaling: Recurring Themes and Quantitative Models

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First edition published 2022

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Library of Congress CataloginginPublication Data

Names: Ferrell, James Ellsworth, author.

Title: Understanding cell signaling : motifs, recurring themes, and the

theory of nonlinear dynamics / James Ferrell.

Description: Boca Raton : Taylor & Francis, 2021. | Includes

bibliographical references and index. | Summary: All living cells

continually detect and respond to external signals. This is true of

prokaryotes, whether they are living alone or in biofilms, and it is

even more manifestly true in multicellular eukaryotes, where

communication between cells and coordination of the cells behavior

enables the organism to function as a unified whole. In large

multicellular organisms like us humans, cells receive signals from their

immediate neighbors through short-range signals like neurotransmitters

and cell-surface molecules. They receive signals from more distant

neighbors via longer-range diffusible molecules like morphogens, and

from still-more distant neighbors by means of hormones that flow through

the circulatory system. And they receive signals from the outside world

via sense organs. Cells also monitor their own internal status, and

there is a great deal of overlap between the cellular components

involved in cell-cell communication and internal monitoring Provided

by publisher.

Identifiers: LCCN 2021007837 (print) | LCCN 2021007838 (ebook) |

ISBN 9780367643836 (hardback) | ISBN 9780815346036 (paperback) |

ISBN 9781003124269 (ebook)

Subjects: LCSH: Cellular signal transduction.

Classification: LCC QP517.C45 F47 2021 (print) | LCC QP517.C45 (ebook) |

DDC 571.7/4--dc23

LC record available at https://lccn.loc.gov/2021007837

LC ebook record available at https://lccn.loc.gov/2021007838

ISBN: 978-0-367-64383-6 (hbk)

ISBN: 978-0-8153-4603-6 (pbk)

ISBN: 978-1-003-12426-9 (ebk)

DOI: 10.1201/9781003124269

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