Trevor W. Stone - CNS Neurotransmitters and Neuromodulators: Acetylcholine

Acetylcholine

Edited by

Trevor W. Stone, Ph.D., D.Sc.

Professor of Pharmacology
Department of Pharmacology
University of Glasgow
Glasgow, Scotland

Library of Congress Cataloging-in-Publication Data

CNS neurotransmitters and neuromodulators : acetylcholine / edited by

Trevor W. Stone.

p. cm.

Includes bibliographical references and index.

ISBN 0-8493-7630-0

1. Acetylcholine--Physiological effect. 2. Cholinergic mechanisms. I. Stone, T. W.

QP364.7.C58 1994

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International Standard Book Number 0-8493-7630-0

Library of Congress Card Number 94-26310

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The rate at which neuroscience research is growing makes it increasingly difficult for active scientists to keep abreast of topics not in their immediate sphere of interest. Despite this, there is undoubtedly much to learn from workers in closely related fields. This group of review volumes, CNS Neurotransmitters and Neuromodulators, is intended to provide an overview in certain areas of neuroscience, covering aspects from molecular to behavioral. These books should be valuable reference and background material for anyone working in the field of neuroscience, and will hopefully encourage discussion between groups of various disciplines, which will make possible major advances in knowledge.

Trevor W. Stone, Ph.D., D.Sc.

Glasgow, Scotland

Trevor W. Stone, Ph.D, D.Sc., is a Professor of Pharmacology at the University of Glasgow in Scotland. Professor Stone graduated in 1969 from the School of Pharmacy at London University and proceeded to the University at Aberdeen in Scotland to take a Ph.D. degree under the supervision of Professor J. Laurence Malcolm. Professor Stone was appointed to a Lectureship in Physiology at Aberdeen, where he remained until 1977 when he was appointed to a senior Lectureship and subsequent Professorship in Neurosciences at St. Georges Medical School in London. He is a member of the British Physiological and Pharmacological Societies, the European and International Neuroscience Research Societies, The American Society for Neuroscience, The Royal Society of Medicine in London, and the New York Academy of Sciences.

Professor Stone has held research appointments at the National Institute of Mental Health in Washington, D.C. and has been Visiting Professor of Pharmacology at the University of Auckland, New Zealand and at the Gulbenkian Institute of Science, Portugal.

Professor Stone has presented invited lectures at international meetings and has published more than 400 research papers and communications. In 1983 Professor Stone was awarded the degree of Doctor of Science by the University of London for his work on the physiology and pharmacology of the nervous system. His current research interests include the pharmacology of synaptic transmission in the nervous system, particularly with respect to amino acids and purines, the interactions between synaptic transmitters, and the role of amino acids in neurological disorders.

Vera Adam-Vizi, M.D., Ph.D., D.Sc.

Department of Biochemistry II

Semmelweis University of Medicine

Budapest, Hungary

Jesse Baumgold, Ph.D.

Departments of Radiology and Pharmacology

The George Washington University Medical Center

Washington, D.C.

Hendrik W. G. M. Boddeke, Ph.D.

Preclinical Research

Sandoz Pharma Ltd.

Basel, Switzerland

Peter H. Boeijinga, Ph.D.

Preclinical Research

Sandoz Pharma Ltd.

Basel, Switzerland

Jennifer A. Court, Ph.D.

MRC Neurochemical Pathology Unit

Newcastle General Hospital

Newcastle-upon-Tyne, England

Esam E. El-Fakahany, Ph.D.

Division of Neuroscience Research in Psychiatry

University of Minnesota Medical School

Minneapolis, Minnesota

Carola Eva, Ph.D.

Istituto di Farmacologia e Terapia Sperimentale

Facolt di Medicina

Universit di Torino

Torino, Italy

Rosalee Grette Lydon

Department of Psychology

Dalhousie University

Halifax, Nova Scotia, Canada

Ricardo Martnez-Murillo, Ph.D.

Department of Chemical Neuroanatomy

Cajal Institute

C.S.I.C.

Madrid, Spain

Hylan C. Moises, Ph.D.

Department of Physiology

University of Michigan Medical School

Ann Arbor, Michigan

Eugenia Monferini, D.Chem.

Department of Biochemistry and Molecular Pharmacolgy

Boehringer Ingelheim Italia

Milano, Italy

Elaine K. Perry, D.Sc.

MRC Neurochemical Pathology Unit

Newcastle General Hospital

Newcastle-upon-Tyne, England

James H. Pirch, Ph.D.

Department of Pharmacology

Texas Tech University Health Sciences Center

Lubbock, Texas

Jos Rodrigo, Ph.D.

Department of Chemical Neuroanatomy

Cajal Institute

C.S.I.C.

Madrid, Spain

Steffen Roner

Department of Neurochemistry

Paul Flechsig Institute for Brain Research

University of Leipzig

Leipzig, Germany

Jennifer M. Rusted, Ph.D.

Laboratory of Experimental Psychology

University of Sussex

Brighton, Sussex, England

Reinhard Schliebs, Ph.D., D.Sc.

Department of Neurochemistry

Paul Flechsig Institute for Brain Research

University of Leipzig