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John A. Timbrell - Study Toxicology through Questions

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This is a compilation of questions with answers for students of toxicology. The questions are a mixture of short answer, problem-solving, data interpretation and multiple choice and cover all the major areas of toxicology, including mechanisms of toxicity, toxic responses, factors affecting the toxicity of compounds and the metabolism and disposition of toxic compounds. The book should also be useful for qualified toxicologists and scientists working in related areas who are preparing for internal examinations.

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Cover

title Study Toxicology Through Questions author Timbrell John A - photo 1
title:Study Toxicology Through Questions
author:Timbrell, John A.
publisher:Taylor & Francis Routledge
isbn10 | asin:
print isbn13:9780203484012
ebook isbn13:9780585461502
language:English
subjectToxicology--Examinations, questions, etc.
publication date:1997
lcc:RA1216.T56 1997eb
ddc:615.9/0076
subject:Toxicology--Examinations, questions, etc.

Page i

Study toxicology through questions

Page ii

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Page iii

Study toxicology through questions

John A.Timbrell
Glaxo Professor of Toxicology
School of Pharmacy
University of London

Page iv UK Taylor Francis Ltd 1 Gunpowder Square London EC4A 3DE USA - photo 2

Page iv

UK Taylor & Francis Ltd., 1 Gunpowder Square, London EC4A 3DE

USA Taylor & Francis Inc., 1900 Frost Road, Suite 101, Bristol, PA 19007

This edition published in the Taylor & Francis e-Library, 2003.

Copyright John A.Timbrell 1997

All rights reserved. No part of this publication may be reproduced, stored
in a retrieval system, or transmitted, in any form or by any
means, electronic, electrostatic, magnetic tape, mechanical, photocopying,
recording or otherwise, without the prior permission of the copyright
owner.

British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library.

ISBN 0-203-48401-0 Master e-book ISBN

ISBN 0-203-22793-X (OEB Format)

ISBN 0-7484-0695-6 (Print Edition)

Library of Congress Cataloguing Publication Data are available

Cover design by Amanda Barragry

Page v

Contents

Preface

Introduction

General toxicology

Multiple choice questions

Short answer questions

Answers

Multiple choice

Short answers

Absorption, distribution and excretion of compounds

Multiple choice questions

Short answer questions

Problem solving questions

Answers

Multiple choice

Short answers

Problem solving

Metabolism of compounds

Page vi

Multiple choice questions

Short answer questions

Problem solving questions

Answers

Multiple choice

Short answers

Problem solving

Factors affecting the toxicity of compounds

Multiple choice questions

Short answer questions

Problem solving questions

Answers

Multiple choice

Short answers

Problem solving

Toxic responses

Multiple choice questions

Short answer questions

Problem solving questions

Answers

Multiple choice

Short answers

Problem solving

Mechanisms of toxicity

Multiple choice questions

Problem solving questions

Answers

Multiple choice

Problem solving

Overall integration of the subject

Problem solving questions

Answers

Problem solving

Page 1

Preface

This book has arisen from my involvement in teaching a BSc course in Toxicology and Pharmacology over the last 16 years. After devising questions of various types over this time I discovered how difficult and time consuming this can be. To refine the questions and put them together into a book with suggested answers seemed a useful endpoint which could be used by toxicologists at all levels.

I wish to thank Andy Shaw for his pharmacokinetics questions and Elaine Stott at Taylor & Francis for her help. However, I am especially grateful to Cathy Waterfield for producing all the figures and setting up the manuscript as camera ready copy, as well as for her patience.

London, April 1997.

Page 2

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Page 3

Introduction

This book is intended for several types of audience:

The student who needs a study aid for toxicology but wants more than a textbook as they need a self-testing regime.

The teacher of toxicology who needs inspiration when composing questions for their students.

The established toxicologist who wants to test their own knowledge or understanding.

It can be used at universities and colleges but also in industry for in-house training courses in toxicology which I know exist in some pharmaceutical and chemical companies.

The questions are a mixture of multiple choice, short answer and problem solving questions and are not meant to reflect a particular level of knowledge or development. Consequently some of the answers may be short whereas others are quite lengthy, even in the same question. are

Although based loosely on Principles of Biochemical Toxicology, this book can be used alongside a number of standard toxicology texts which are listed below.

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