Casarett & Doulls Essentials of Toxicology
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Casarett & Doulls Essentials of Toxicology
Second Edition
Editors
Curtis D. Klaassen, PhD
University Distinguished Professor and Chair
Department of Pharmacology, Toxicology, and Therapeutics
University of Kansas Medical Center
Kansas City, Kansas
John B. Watkins III, PhD
Assistant Dean and Director
Professor of Pharmacology and Toxicology
Medical Sciences Program
Indiana University School of Medicine
Bloomington, Indiana
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ISBN: 978-0-07-176651-7
MHID: 0-07-176651-0
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Contents
Michael A. Gallo
David L. Eaton and Steven G. Gilbert
Zoltn Gregus
Elaine M. Faustman and Gilbert S. Omenn
Lois D. Lehman-McKeeman
Andrew Parkinson and Brian W. Ogilvie
Danny D. Shen
James E. Klaunig and Lisa M. Kamendulis
R. Julian Preston and George R. Hoffmann
John M. Rogers and Robert J. Kavlock
John C. Bloom and John T. Brandt
Norbert E. Kaminski, Barbara L. Faubert Kaplan, and Michael P. Holsapple
Hartmut Jaeschke
Rick G. Schnellmann
Hanspeter R. Witschi, Kent E. Pinkerton, Laura S. Van Winkle, and Jerold A. Last
Virginia C. Moser, Michael Aschner, Rudy J. Richardson, and Martin A. Philbert
Donald A. Fox and William K. Boyes
Y. James Kang
Robert H. Rice and Theodora M. Mauro
Paul M. D. Foster and L. Earl Gray Jr.
Charles C. Capen
Lucio G. Costa
Jie Liu, Robert A. Goyer, and Michael P. Waalkes
James V. Bruckner, S. Satheesh Anand and D. Alan Warren
Naomi H. Harley
John B. Watkins III
Stata Norton
Daniel L. Costa
Richard T. Di Giulio and Michael C. Newman
Frank N. Kotsonis and George A. Burdock
Alphonse Poklis
Louis R. Cantilena Jr.
Peter S. Thorne
Contributors
Michael Aschner, PhD
Gray E.B. Stahlman Chair in Neuroscience,
Professor of Pediatrics and Pharmacology and
Senior Investigator of the Kennedy Center,
Vanderbilt University, Nashville, Tennessee
S. Satheesh Anand, PhD
Research Toxicologist, DuPont Haskell Laboratory for
Health and Environmental Sciences, Newark, Delaware
John C. Bloom, VMD, PhD
Executive Director, Distinguished Medical Fellow,
Diagnostic and Experimental Medicine,
Eli Lilly and Company, Indianapolis, Indiana
William K. Boyes, PhD
Neurotoxicology Division
National Health and Environmental Effects Research
Laboratory, Office of Research and Development,
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