Jie Xu - Regulation of Cancer Immune Checkpoints: Molecular and Cellular Mechanisms and Therapy

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Volume 1248

Advances in Experimental Medicine and Biology

Series Editors

Wim E. Crusio

Institut de Neurosciences Cognitives et Intgratives dAquitaine, CNRS and University of Bordeaux UMR 5287, Pessac Cedex, France

John D. Lambris

University of Pennsylvania, Philadelphia, PA, USA

Heinfried H. Radeke

Institute of Pharmacology & Toxicology, Clinic of the Goethe University Frankfurt Main, Frankfurt am Main, Germany

Nima Rezaei

Research Center for Immunodeficiencies, Childrens Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Advances in Experimental Medicine and Biologyprovides a platform for scientific contributions in the main disciplines of the biomedicine and the life sciences. This series publishes thematic volumes on contemporary research in the areas of microbiology, immunology, neurosciences, biochemistry, biomedical engineering, genetics, physiology, and cancer research. Covering emerging topics and techniques in basic and clinical science, it brings together clinicians and researchers from various fields.

Advances in Experimental Medicine and Biologyhas been publishing exceptional works in the field for over 40 years, and is indexed in SCOPUS, Medline (PubMed), Journal Citation Reports/Science Edition, Science Citation Index Expanded (SciSearch, Web of Science), EMBASE, BIOSIS, Reaxys, EMBiology, the Chemical Abstracts Service (CAS), and Pathway Studio.

2018 Impact Factor: 2.126.

More information about this series at http://www.springer.com/series/5584

Editor

Jie Xu

Regulation of Cancer Immune Checkpoints

Molecular and Cellular Mechanisms and Therapy

Editor

Jie Xu

Institutes of Biomedical Sciences, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China

ISSN 0065-2598 e-ISSN 2214-8019

Advances in Experimental Medicine and Biology

ISBN 978-981-15-3265-8 e-ISBN 978-981-15-3266-5

https://doi.org/10.1007/978-981-15-3266-5

Springer Nature Singapore Pte Ltd. 2020

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.

The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd.

The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Contents

Jie Liu and Jie Xu

Samya Van Coillie , Bartosz Wiernicki and Jie Xu

Luoyan Ai , Antao Xu and Jie Xu

Xuan Kong

Hubing Shi , Jiang Lan and Jiqiao Yang

Shan Sun and Feng Wang

Qianqian Hou and Heng Xu

Wenhua Li , Jingbo Qie , Yao Zhang and Jinjia Chang

Yaping Zhang and Junke Zheng

Shuai Ding , Siqi Li , Shujie Zhang and Yan Li

Jean-Philippe Brosseau

Chushu Li , Bingqing Xia , Sheng Wang and Jie Xu

Han Yao and Jie Xu

Huanbin Wang , Xue Han and Jie Xu

Yiting Wang , Ping Wang and Jie Xu

Yiting Wang , Haojie Lu , Caiyun Fang and Jie Xu

Haojie Lu and Caiyun Fang

Shouyan Deng , Xiaolin Zhou and Jie Xu

Ye Hu , Rui Zhang and Gang Chen

Xiao-Dong Su and Yao Shuai

Yunsheng Yuan

Yongxin Han , Li Zhu , Wei Wu , Hui Zhang , Wei Hu , Liguang Dai and Yanqing Yang

Jilin Wang , Teddy Yang and Jie Xu

Jie Xu and Mingyao Liu

Contributors

Luoyan Ai

Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China

Jean-Philippe Brosseau

Department of Biochemistry and functional Genomics, University of Sherbrooke, Sherbrooke, Canada

Jinjia Chang

Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China

Gang Chen

The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, Peoples Republic of China

Liguang Dai

PrimeGene (Beijing) Co., Ltd., Beijing, China

Shouyan Deng

Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Shuai Ding

The State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Model Animal Research Center of Nanjing University, Nanjing, Jiangsu, China

Caiyun Fang

Department of Chemistry, Institutes of Biomedical Sciences, Fudan University, Shanghai, China

Xue Han

Institutes of Biological Sciences, Fudan University, Shanghai, China

Yongxin Han

Lapam Capital LLC., Beijing, China

Qianqian Hou

Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

Wei Hu

PrimeGene (Beijing) Co., Ltd., Beijing, China

Ye Hu

Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Womens Cancer Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Xuan Kong

Bristol Myers Squibb Global Clinical Research, Shanghai, China

Jiang Lan

The State Key Laboratory of Biotherapy, Sichuan University West China Hospital, Chengdu, China

Chushu Li

Renji Hospital, Shanghai Jiao Tong University, Shanghai, China

Siqi Li

The State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Model Animal Research Center of Nanjing University, Nanjing, Jiangsu, China

Wenhua Li

Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China

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