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Ashutosh Kumar Shukla - Nanoparticles in Medicine

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Ashutosh Kumar Shukla Nanoparticles in Medicine

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This book describes the medical applications of inorganic nanoparticles. Nanomedicine is a relatively advanced field, which enhances the treatment of various diseases, offering new options for overcoming the problems associated with the use of conventional medicines. Discussing the toxicological and safety aspects associated with medical applications of nanoparticles, the book presents the latest research on topics such as emerging nanomaterials for cancer therapy, applications of nanoparticles in dentistry, and fluoride nanoparticles for biomedical applications, and also includes chapters on the use of nanoparticles such as silver and gold. /div

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Editor Ashutosh Kumar Shukla Nanoparticles in Medicine Editor - photo 1
Editor
Ashutosh Kumar Shukla
Nanoparticles in Medicine
Editor Ashutosh Kumar Shukla Physics Department Ewing Christian College - photo 2
Editor
Ashutosh Kumar Shukla
Physics Department, Ewing Christian College, University of Allahabad, Allahabad, Uttar Pradesh, India
ISBN 978-981-13-8953-5 e-ISBN 978-981-13-8954-2
https://doi.org/10.1007/978-981-13-8954-2
Springer Nature Singapore Pte Ltd. 2020
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd.

The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

To my parents.

Preface

This collection intends to highlight the potential applications of nanoparticles in medicine. Gold and silver nanoparticles, rare earth-doped fluoride nanoparticles, protein-based nanoparticles, and fungal-mediated nanoparticles have been covered in different chapters. The applications in different fields of medicine covered in this volume include cancer therapy, photodynamic therapy, antioxidant therapy, dentistry, and caries prevention. Related toxicity issues have been addressed in individual chapters and in a separate chapter as well.

I am thankful to the expert contributors for contributing to this volume. My special thanks to Prof. Alex I. Smirnov, Department of Chemistry, North Carolina State University, USA; Prof. Anjana Pandey, Department of Biotechnology, MNNIT, Allahabad; Dr. Chitta Ranjan Patra, Department of Applied Biology, CSIR-IICT, Hyderabad; Dr. Monalisa Mishra, Department of Life Science, NIT, Rourkela; and Dr. S Rajeshkumar, Department of Pharmacology, Saveetha Dental College, Chennai, who kindly reviewed the manuscripts for this volume.

I sincerely thank Dr. Naren Aggarwal, Executive Editor, Clinical Medicine, Springer (India) Private Limited, for giving me the opportunity to present this book to the readers. I also thank Teena Bedi, Associate Editor, Clinical Medicine, Springer (India) Private Limited, and Mr. Ejaz Ahmad, Project Coordinator (Books), for their support during the publication process.

It was a good learning experience for me to go through individual chapters and hope that it will be a good experience for the audience too.

Ashutosh Kumar Shukla
Allahabad, India
May 2019
Contents
Sourav Das , Manideep Pabba , M. E. Dhushyandhun and Chitta Ranjan Patra
Sanjay Kumar , Pratibha Kumari and Rajeev Singh
Subhashree Priyadarsini , Sumit Mukherjee , Janmejaya Bag , Nibedita Nayak and Monalisa Mishra
Annuja Anandaradje , Vadivel Meyappan , Indramani Kumar and Natarajan Sakthivel
M. S. Pudovkin and R. M. Rakhmatullin
Siavash Iravani and Ghazaleh Jamalipour Soufi
S. Rajeshkumar and D. Sivapriya
Sharda Sundaram Sanjay
About the Editor
Ashutosh Kumar Shukla

holds B.Sc., M.Sc., and D. Phil. degrees from the University of Allahabad. His doctoral research involved using electron spin resonance spectroscopy and optical absorption spectroscopy to investigate transition ion-doped single crystals. He has been a university teacher and researcher for 17 years and is currently an Associate Professor of Physics at Ewing Christian College, Allahabad, a University of Allahabad institution. He also served as an Associate Professor (Pure and Applied Physics) at Guru Ghasidas Vishwavidyalaya, Bilaspur, C.G. (a central university).

Dr. Shukla has successfully completed research projects in the area of electron spin resonance, funded by the University Grants Commission, Indias main higher education body. He has presented his research at various international events in countries including the USA, UK, Germany, Spain, and Russia. He has published a number of research papers in peer-reviewed journals and has edited numerous volumes. He has delivered several invited lectures on characterization techniques at national and international conferences and workshops. He also reviews manuscripts for a number of international journals.

He has received many scholarships and fellowships, including a National Scholarship; Government of U. P. Ministry of Higher Education Scholarship; and research fellowships from the Council of Science & Technology, Lucknow; Council of Scientific & Industrial Research, New Delhi; and the Indian National Science Academy-Bilateral Exchange Fellowship.

Springer Nature Singapore Pte Ltd. 2020
A. K. Shukla (ed.) Nanoparticles in Medicine https://doi.org/10.1007/978-981-13-8954-2_1
1. Theranostic Applications of Lysozyme-Based Nanoparticles
Sourav Das
(1)
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India
(2)
Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana, India
Chitta Ranjan Patra
Email:
Keywords
Lysozyme Nanoparticles Biological activity Amyloid Theranostic applications
Abbreviations
A549

Adenocarcinomic human alveolar basal epithelial cells

ABTS

2,2-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)

AgNPs

Silver nanoparticles

AuNCs

Lysozyme-gold nanocluster

CD

Circular dichroism

CF

Cystic fibrosis

CMC

Critical micelle concentrations

COPD

Chronic obstructive pulmonary diseases

CuNCs

Copper nanocluster

EDTA

Ethylenediaminetetraacetic acid

EGF

Epidermal growth factor

FRET

Forster non-radiative energy transfer

FT-IR

Fourier-transform infrared spectroscopy

HeLa

Cervical cancer cells (human)

HGT

Horizontal gene transfer

hLYS

Human lysozyme

HPLC

High-performance liquid chromatography

LOD

Lowest detection limit

LYMB

Lysozyme microbubble

MALDI

Matrix-assisted laser desorption/ionization

MCF-7

Michigan cancer foundation-7

MD

Molecular dynamics

MIC

Minimum inhibitory concentration

NAG-3

N-acetyl- d -glucosamine

NC
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