Editor
Ashutosh Kumar Shukla
Nanoparticles in Medicine
Editor
Ashutosh Kumar Shukla
Physics Department, Ewing Christian College, University of Allahabad, Allahabad, Uttar Pradesh, India
ISBN 978-981-13-8953-5 e-ISBN 978-981-13-8954-2
https://doi.org/10.1007/978-981-13-8954-2
Springer Nature Singapore Pte Ltd. 2020
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To my parents.
Preface
This collection intends to highlight the potential applications of nanoparticles in medicine. Gold and silver nanoparticles, rare earth-doped fluoride nanoparticles, protein-based nanoparticles, and fungal-mediated nanoparticles have been covered in different chapters. The applications in different fields of medicine covered in this volume include cancer therapy, photodynamic therapy, antioxidant therapy, dentistry, and caries prevention. Related toxicity issues have been addressed in individual chapters and in a separate chapter as well.
I am thankful to the expert contributors for contributing to this volume. My special thanks to Prof. Alex I. Smirnov, Department of Chemistry, North Carolina State University, USA; Prof. Anjana Pandey, Department of Biotechnology, MNNIT, Allahabad; Dr. Chitta Ranjan Patra, Department of Applied Biology, CSIR-IICT, Hyderabad; Dr. Monalisa Mishra, Department of Life Science, NIT, Rourkela; and Dr. S Rajeshkumar, Department of Pharmacology, Saveetha Dental College, Chennai, who kindly reviewed the manuscripts for this volume.
I sincerely thank Dr. Naren Aggarwal, Executive Editor, Clinical Medicine, Springer (India) Private Limited, for giving me the opportunity to present this book to the readers. I also thank Teena Bedi, Associate Editor, Clinical Medicine, Springer (India) Private Limited, and Mr. Ejaz Ahmad, Project Coordinator (Books), for their support during the publication process.
It was a good learning experience for me to go through individual chapters and hope that it will be a good experience for the audience too.
Ashutosh Kumar Shukla
Allahabad, India
May 2019
Contents
Sourav Das , Manideep Pabba , M. E. Dhushyandhun and Chitta Ranjan Patra
Sanjay Kumar , Pratibha Kumari and Rajeev Singh
Subhashree Priyadarsini , Sumit Mukherjee , Janmejaya Bag , Nibedita Nayak and Monalisa Mishra
Annuja Anandaradje , Vadivel Meyappan , Indramani Kumar and Natarajan Sakthivel
M. S. Pudovkin and R. M. Rakhmatullin
Siavash Iravani and Ghazaleh Jamalipour Soufi
S. Rajeshkumar and D. Sivapriya
Sharda Sundaram Sanjay
About the Editor
Ashutosh Kumar Shukla
holds B.Sc., M.Sc., and D. Phil. degrees from the University of Allahabad. His doctoral research involved using electron spin resonance spectroscopy and optical absorption spectroscopy to investigate transition ion-doped single crystals. He has been a university teacher and researcher for 17 years and is currently an Associate Professor of Physics at Ewing Christian College, Allahabad, a University of Allahabad institution. He also served as an Associate Professor (Pure and Applied Physics) at Guru Ghasidas Vishwavidyalaya, Bilaspur, C.G. (a central university).
Dr. Shukla has successfully completed research projects in the area of electron spin resonance, funded by the University Grants Commission, Indias main higher education body. He has presented his research at various international events in countries including the USA, UK, Germany, Spain, and Russia. He has published a number of research papers in peer-reviewed journals and has edited numerous volumes. He has delivered several invited lectures on characterization techniques at national and international conferences and workshops. He also reviews manuscripts for a number of international journals.
He has received many scholarships and fellowships, including a National Scholarship; Government of U. P. Ministry of Higher Education Scholarship; and research fellowships from the Council of Science & Technology, Lucknow; Council of Scientific & Industrial Research, New Delhi; and the Indian National Science Academy-Bilateral Exchange Fellowship.
1. Theranostic Applications of Lysozyme-Based Nanoparticles
Abbreviations
A549
Adenocarcinomic human alveolar basal epithelial cells
ABTS
2,2-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)
AgNPs
Silver nanoparticles
AuNCs
Lysozyme-gold nanocluster
CD
Circular dichroism
CF
Cystic fibrosis
CMC
Critical micelle concentrations
COPD
Chronic obstructive pulmonary diseases
CuNCs
Copper nanocluster
EDTA
Ethylenediaminetetraacetic acid
EGF
Epidermal growth factor
FRET
Forster non-radiative energy transfer
FT-IR
Fourier-transform infrared spectroscopy
HeLa
Cervical cancer cells (human)
HGT
Horizontal gene transfer
hLYS
Human lysozyme
HPLC
High-performance liquid chromatography
LOD
Lowest detection limit
LYMB
Lysozyme microbubble
MALDI
Matrix-assisted laser desorption/ionization
MCF-7
Michigan cancer foundation-7
MD
Molecular dynamics
MIC
Minimum inhibitory concentration
NAG-3
N-acetyl- d -glucosamine
NC